NEUCR:Q872F8

Species (Taxon ID)	Neurospora crassa. (5141)
Gene Name(s)	80A10.170 (ECO:0000313 with EMBL:CAD70774.1)
Protein Name(s)	Probable dihydroxy-acid dehydratase (ECO:0000313 with EMBL:CAD70774.1)
External Links
UniProt	Q872F8
EMBL	BX294012
ProteinModelPortal	Q872F8
STRING	5141.NCU04579.1
eggNOG	COG0129
HOGENOM	HOG000173155
PhylomeDB	Q872F8
GO	GO:0004160 GO:0009082
HAMAP	MF_00012
InterPro	IPR015928 IPR004404 IPR000581 IPR020558
PANTHER	PTHR21000
Pfam	PF00920
SUPFAM	SSF52016
TIGRFAMs	TIGR00110
PROSITE	PS00886 PS00887

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0009097	isoleucine biosynthetic process	PMID:17248057	ECO:0000315			P		The iv-1 mutants illustrated in Table 2 and the following discussion have been shown to accumulate dihydroxy-methylvaleric acid and dihydroxy isovaleric acid, two direct percursors for isoleucine and valien synthesis. The same mutants were also shown not to grow on minimal medium, but did grow on minimal medium supplemented with isoleucine and valine	complete
	GO:0009099	valine biosynthetic process	PMID:17248057	ECO:0000315			P		The iv-1 mutants illustrated in Table 2 and the following discussion have been shown to accumulate dihydroxy-methylvaleric acid and dihydroxy isovaleric acid, two direct percursors for isoleucine and valien synthesis. The same mutants were also shown not to grow on minimal medium, but did grow on minimal medium supplemented with isoleucine and valine	complete
	GO:0004160	dihydroxy-acid dehydratase activity	PMID:17248057	ECO:0000315			F		The iv-1 mutants accumulate the direct precursor to the dehydratase reaction, inferring their defect must be in this enzyme.	complete
enables	GO:0003824	catalytic activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000581 InterPro:IPR020558	F		Seeded From UniProt	complete
enables	GO:0004160	dihydroxy-acid dehydratase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004404	F		Seeded From UniProt	complete
involved_in	GO:0009082	branched-chain amino acid biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR004404	P		Seeded From UniProt	complete
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References

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