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PMID:17248057
| Citation |
Bernstein, H and Miller, A (1961) Complementation Studies with Isoleucine-Valine Mutants of Neurospora Crassa. Genetics 46:1039-52 |
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| Abstract |
No abstract in PubMed |
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| Keywords |
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Significance
Annotations
| Gene product | Qualifier | GO Term | Evidence Code | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0009099: valine biosynthetic process |
ECO:0000315: |
P |
The iv-1 mutants illustrated in Table 2 and the following discussion have been shown to accumulate dihydroxy-methylvaleric acid and dihydroxy isovaleric acid, two direct percursors for isoleucine and valien synthesis. The same mutants were also shown not to grow on minimal medium, but did grow on minimal medium supplemented with isoleucine and valine |
complete | ||||
| GO:0004160: dihydroxy-acid dehydratase activity |
ECO:0000315: |
F |
The iv-1 mutants accumulate the direct precursor to the dehydratase reaction, inferring their defect must be in this enzyme. |
complete | ||||
| GO:0009097: isoleucine biosynthetic process |
ECO:0000315: |
P |
The iv-1 mutants illustrated in Table 2 and the following discussion have been shown to accumulate dihydroxy-methylvaleric acid and dihydroxy isovaleric acid, two direct percursors for isoleucine and valien synthesis. The same mutants were also shown not to grow on minimal medium, but did grow on minimal medium supplemented with isoleucine and valine |
complete | ||||
See also
References
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