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MYCTU:PPE18

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Species (Taxon ID) Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv). (83332)
Gene Name(s) PPE18 (ECO:0000312 with EMBL:CCP43952.1)
Protein Name(s) PPE family protein PPE18 (ECO:0000305)
External Links
UniProt L7N675
EMBL CP009480
AL123456
RefSeq WP_003898765.1
YP_177795.1
ProteinModelPortal L7N675
SMR L7N675
STRING 83332.Rv1196
EnsemblBacteria AIR13943
CCP43952
GeneID 886073
KEGG mtu:Rv1196
mtv:RVBD_1196
TubercuList Rv1196
OMA ANNHVSM
PhylomeDB L7N675
Proteomes UP000001584
UP000031768
GO GO:0009986
GO:0005618
GO:0005576
GO:0009405
InterPro IPR022171
IPR000030
Pfam PF12484
PF00823

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0051701

biological process involved in interaction with host

PMID:23300718[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Figure 1: C57BL/6 mice were infected aerogenically with a low dose (1x10^8) of either WT or ppe18 KO strains of Mtb. At different time points post infection, mice were sacrificed and CFU counts were measured in lung (A), liver (B) and spleen (C). Lower CFU recovered of the ppe18 KO compared to WT in all three tissues.

complete
CACAO 12538

involved_in

GO:0009405

obsolete pathogenesis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

P

Seeded From UniProt

complete

part_of

GO:0005618

cell wall

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0134
UniProtKB-SubCell:SL-0041

C

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0964

C

Seeded From UniProt

complete

part_of

GO:0009986

cell surface

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0310

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Bhat, KH et al. (2012) Role of PPE18 protein in intracellular survival and pathogenicity of Mycobacterium tuberculosis in mice. PLoS ONE 7 e52601 PubMed GONUTS page