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MYCTU:LSR2
Contents
| Species (Taxon ID) | Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv). (83332) | |
| Gene Name(s) | lsr2 | |
| Protein Name(s) | Nucleoid-associated protein Lsr2 | |
| External Links | ||
| UniProt | P9WIP7 | |
| EMBL | AL123456 | |
| PIR | F70954 | |
| RefSeq | NP_218114.1 YP_006517087.1 | |
| PDB | 2KNG 4E1P 4E1R | |
| PDBsum | 2KNG 4E1P 4E1R | |
| ProteinModelPortal | P9WIP7 | |
| SMR | P9WIP7 | |
| GeneID | 13317206 885580 | |
| KEGG | mtu:Rv3597c mtv:RVBD_3597c | |
| TubercuList | Rv3597c | |
| OMA | SIDREQS | |
| PhylomeDB | P9WIP7 | |
| Proteomes | UP000001584 | |
| GO | GO:0005618 GO:0005829 GO:0009295 GO:0005886 GO:0003677 GO:0042262 GO:0040007 GO:0009405 GO:0006355 GO:0042542 GO:0010039 GO:0006351 | |
| InterPro | IPR024412 | |
| Pfam | PF11774 | |
| ProDom | PD026347 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0003677 |
DNA binding |
ECO:0000314 |
F |
The data from the Figures represents the influence of gene expression. |
complete | |||||
|
involved_in |
GO:0071453 |
cellular response to oxygen levels |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009405 |
pathogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005618 |
cell wall |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005618 |
cell wall |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042542 |
response to hydrogen peroxide |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042262 |
DNA protection |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0010039 |
response to iron ion |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0009405 |
pathogenesis |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0009295 |
nucleoid |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Ghosh, S et al. (2013) Regulation of lipid biosynthesis, sliding motility, and biofilm formation by a membrane-anchored nucleoid-associated protein of Mycobacterium tuberculosis. J. Bacteriol. 195 1769-78 PubMed GONUTS page
- ↑ 2.0 2.1 Bartek, IL et al. (2014) Mycobacterium tuberculosis Lsr2 is a global transcriptional regulator required for adaptation to changing oxygen levels and virulence. MBio 5 e01106-14 PubMed GONUTS page
- ↑ Gu, S et al. (2003) Comprehensive proteomic profiling of the membrane constituents of a Mycobacterium tuberculosis strain. Mol. Cell Proteomics 2 1284-96 PubMed GONUTS page
- ↑ 4.0 4.1 Mawuenyega, KG et al. (2005) Mycobacterium tuberculosis functional network analysis by global subcellular protein profiling. Mol. Biol. Cell 16 396-404 PubMed GONUTS page
- ↑ Wolfe, LM et al. (2010) Proteomic definition of the cell wall of Mycobacterium tuberculosis. J. Proteome Res. 9 5816-26 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Colangeli, R et al. (2009) The multifunctional histone-like protein Lsr2 protects mycobacteria against reactive oxygen intermediates. Proc. Natl. Acad. Sci. U.S.A. 106 4414-8 PubMed GONUTS page
- ↑ Wong, DK et al. (1999) Identification of fur, aconitase, and other proteins expressed by Mycobacterium tuberculosis under conditions of low and high concentrations of iron by combined two-dimensional gel electrophoresis and mass spectrometry. Infect. Immun. 67 327-36 PubMed GONUTS page
- ↑ Gordon, BR et al. (2008) Lsr2 of Mycobacterium represents a novel class of H-NS-like proteins. J. Bacteriol. 190 7052-9 PubMed GONUTS page
- ↑ Chen, JM et al. (2008) Lsr2 of Mycobacterium tuberculosis is a DNA-bridging protein. Nucleic Acids Res. 36 2123-35 PubMed GONUTS page
