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MOUSE:TRPC7

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Trpc7 (synonyms: Trp7, Trrp8)
Protein Name(s) Short transient receptor potential channel 7

TrpC7 Transient receptor protein 7 TRP-7 mTRP7

External Links
UniProt Q9WVC5
EMBL AF139923
CCDS CCDS26566.1
RefSeq NP_036165.1
UniGene Mm.62409
ProteinModelPortal Q9WVC5
SMR Q9WVC5
MINT MINT-4998494
STRING 10090.ENSMUSP00000022023
GuidetoPHARMACOLOGY 492
TCDB 1.A.4.1.2
PhosphoSite Q9WVC5
PaxDb Q9WVC5
PRIDE Q9WVC5
Ensembl ENSMUST00000022023
GeneID 26946
KEGG mmu:26946
UCSC uc007qtb.1
CTD 57113
MGI MGI:1349470
eggNOG NOG254238
GeneTree ENSGT00760000119180
HOGENOM HOG000020590
HOVERGEN HBG068337
InParanoid Q9WVC5
KO K04970
OMA GSNTFKN
OrthoDB EOG77HDD1
PhylomeDB Q9WVC5
TreeFam TF313147
Reactome REACT_219232
REACT_227667
REACT_227861
REACT_230631
NextBio 304881
PRO PR:Q9WVC5
Proteomes UP000000589
Bgee Q9WVC5
ExpressionAtlas Q9WVC5
Genevestigator Q9WVC5
GO GO:0005801
GO:0016021
GO:0005635
GO:0048471
GO:0005886
GO:0005262
GO:0006816
GO:0006828
Gene3D 1.25.40.20
InterPro IPR002110
IPR020683
IPR005821
IPR004729
IPR013555
IPR005463
IPR002153
PANTHER PTHR10117
PTHR10117:SF9
Pfam PF12796
PF00520
PF08344
PRINTS PR01097
PR01648
SMART SM00248
SUPFAM SSF48403
TIGRFAMs TIGR00870

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0070679

inositol 1,4,5 trisphosphate binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:109524
MGI:MGI:109525
MGI:MGI:109527
PANTHER:PTN000012230
UniProtKB:P48995
UniProtKB:Q13507
UniProtKB:Q9Y210

F

Seeded From UniProt

complete

involved_in

GO:0070588

calcium ion transmembrane transport

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0003861
FB:FBgn0005614
PANTHER:PTN000012230
UniProtKB:Q13507

P

Seeded From UniProt

complete

involved_in

GO:0051480

regulation of cytosolic calcium ion concentration

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000012230
UniProtKB:P48995

P

Seeded From UniProt

complete

part_of

GO:0034703

cation channel complex

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0003861
FB:FBgn0005614
FB:FBgn0032593
PANTHER:PTN000012230

C

Seeded From UniProt

complete

enables

GO:0015279

store-operated calcium channel activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:109523
MGI:MGI:109525
MGI:MGI:109527
MGI:MGI:109528
PANTHER:PTN000012230
UniProtKB:Q9UBN4
WB:WBGene00004976

F

Seeded From UniProt

complete

involved_in

GO:0007338

single fertilization

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001298123
WB:WBGene00004976

P

Seeded From UniProt

complete

involved_in

GO:0006828

manganese ion transport

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1349470
PANTHER:PTN000012230

P

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000012230
RGD:621276
UniProtKB:Q13507
WB:WBGene00004976

C

Seeded From UniProt

complete

part_of

GO:0048471

perinuclear region of cytoplasm

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:628820

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

PMID:10488066[2]

ECO:0000305

curator inference used in manual assertion

GO:0015279

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006828

manganese ion transport

PMID:10488066[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006816

calcium ion transport

PMID:10488066[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

colocalizes_with

GO:0005801

cis-Golgi network

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:628820

C

Seeded From UniProt

complete

enables

GO:0005262

calcium channel activity

PMID:10488066[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0048471

perinuclear region of cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:F1LQF7
ensembl:ENSRNOP00000016982

C

Seeded From UniProt

complete

part_of

GO:0005801

cis-Golgi network

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:F1LQF7
ensembl:ENSRNOP00000016982

C

Seeded From UniProt

complete

enables

GO:0005216

ion channel activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005821

F

Seeded From UniProt

complete

enables

GO:0005262

calcium channel activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002153
InterPro:IPR005463

F

Seeded From UniProt

complete

involved_in

GO:0006811

ion transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005821

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002153
InterPro:IPR005821

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005463

C

Seeded From UniProt

complete

involved_in

GO:0055085

transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR005821

P

Seeded From UniProt

complete

involved_in

GO:0070588

calcium ion transmembrane transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR002153
InterPro:IPR005463

P

Seeded From UniProt

complete

involved_in

GO:0006816

calcium ion transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0109

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539

C

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

enables

GO:0005262

calcium channel activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0107

F

Seeded From UniProt

complete

involved_in

GO:0070588

calcium ion transmembrane transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0107

P

Seeded From UniProt

complete

involved_in

GO:0006811

ion transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0406

P

Seeded From UniProt

complete

part_of

GO:0005635

nuclear envelope

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0178

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Okada, T et al. (1999) Molecular and functional characterization of a novel mouse transient receptor potential protein homologue TRP7. Ca(2+)-permeable cation channel that is constitutively activated and enhanced by stimulation of G protein-coupled receptor. J. Biol. Chem. 274 27359-70 PubMed GONUTS page