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MOUSE:THTPA
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Thtpa | |
| Protein Name(s) | Thiamine-triphosphatase
ThTPase | |
| External Links | ||
| UniProt | Q8JZL3 | |
| EMBL | AF432864 AK132479 BC025562 | |
| CCDS | CCDS27108.1 | |
| RefSeq | NP_694723.1 | |
| UniGene | Mm.319204 | |
| PDB | 2JMU | |
| PDBsum | 2JMU | |
| ProteinModelPortal | Q8JZL3 | |
| SMR | Q8JZL3 | |
| IntAct | Q8JZL3 | |
| MINT | MINT-4137740 | |
| PhosphoSite | Q8JZL3 | |
| MaxQB | Q8JZL3 | |
| PaxDb | Q8JZL3 | |
| PRIDE | Q8JZL3 | |
| DNASU | 105663 | |
| Ensembl | ENSMUST00000050575 | |
| GeneID | 105663 | |
| KEGG | mmu:105663 | |
| UCSC | uc007tyb.2 | |
| CTD | 79178 | |
| MGI | MGI:2446078 | |
| eggNOG | NOG42323 | |
| GeneTree | ENSGT00390000005996 | |
| HOGENOM | HOG000154571 | |
| HOVERGEN | HBG057173 | |
| InParanoid | Q8JZL3 | |
| KO | K05307 | |
| OMA | RDTYYDT | |
| OrthoDB | EOG7288SN | |
| PhylomeDB | Q8JZL3 | |
| TreeFam | TF333398 | |
| Reactome | REACT_223427 | |
| EvolutionaryTrace | Q8JZL3 | |
| NextBio | 357818 | |
| PRO | PR:Q8JZL3 | |
| Proteomes | UP000000589 | |
| Bgee | Q8JZL3 | |
| CleanEx | MM_THTPA | |
| Genevestigator | Q8JZL3 | |
| GO | GO:0005737 GO:0000287 GO:0050333 GO:0016311 GO:0042357 GO:0006772 | |
| Gene3D | 2.40.320.10 | |
| InterPro | IPR023577 IPR012177 | |
| Pfam | PF01928 | |
| PIRSF | PIRSF036561 | |
| SUPFAM | SSF55154 | |
| PROSITE | PS51707 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0031625 |
ubiquitin protein ligase binding |
ECO:0000021 |
|
F |
Figure 2 and 3 both show ThTpase activity with the protein |
complete | ||||
| GO:0005515 |
protein binding |
ECO:0000021 |
|
F |
Figure 2 and 3 both show ThTpase activity with the protein |
complete | ||||
|
enables |
GO:0050333 |
thiamin-triphosphatase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050333 |
thiamin-triphosphatase activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042357 |
thiamine diphosphate metabolic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0000287 |
magnesium ion binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050333 |
thiamin-triphosphatase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2446078 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042357 |
thiamine diphosphate metabolic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2446078 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0016311 |
dephosphorylation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001026440 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0000287 |
magnesium ion binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2446078 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0050333 |
thiamin-triphosphatase activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0016311 |
dephosphorylation |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050333 |
thiamin-triphosphatase activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9BU02 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0016311 |
dephosphorylation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q9BU02 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006772 |
thiamine metabolic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050333 |
thiamin-triphosphatase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050333 |
thiamin-triphosphatase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Gangolf, M et al. (2010) Thiamine status in humans and content of phosphorylated thiamine derivatives in biopsies and cultured cells. PLoS ONE 5 e13616 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Song, J et al. (2008) Structural basis for the catalytic mechanism of mammalian 25-kDa thiamine triphosphatase. J. Biol. Chem. 283 10939-48 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
