GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
MOUSE:THIC
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Acat2 | |
| Protein Name(s) | Acetyl-CoA acetyltransferase, cytosolic
Cytosolic acetoacetyl-CoA thiolase | |
| External Links | ||
| UniProt | Q8CAY6 | |
| EMBL | AK013275 AK037249 AK166813 AK167234 BC004823 BC012496 M35797 | |
| CCDS | CCDS37437.1 | |
| PIR | A53174 | |
| RefSeq | NP_033364.2 | |
| UniGene | Mm.439711 | |
| ProteinModelPortal | Q8CAY6 | |
| SMR | Q8CAY6 | |
| IntAct | Q8CAY6 | |
| MINT | MINT-1864806 | |
| PhosphoSite | Q8CAY6 | |
| REPRODUCTION-2DPAGE | Q8CAY6 | |
| MaxQB | Q8CAY6 | |
| PaxDb | Q8CAY6 | |
| PRIDE | Q8CAY6 | |
| Ensembl | ENSMUST00000007005 | |
| GeneID | 110460 | |
| KEGG | mmu:110460 | |
| UCSC | uc008alp.1 | |
| CTD | 39 | |
| MGI | MGI:87871 | |
| eggNOG | COG0183 | |
| GeneTree | ENSGT00390000009412 | |
| HOGENOM | HOG000012238 | |
| HOVERGEN | HBG003112 | |
| InParanoid | Q8CAY6 | |
| KO | K00626 | |
| OMA | RTGQRMG | |
| OrthoDB | EOG7JQBNG | |
| PhylomeDB | Q8CAY6 | |
| TreeFam | TF300650 | |
| NextBio | 364019 | |
| PRO | PR:Q8CAY6 | |
| Proteomes | UP000000589 | |
| Bgee | Q8CAY6 | |
| CleanEx | MM_ACAT2 | |
| ExpressionAtlas | Q8CAY6 | |
| Genevestigator | Q8CAY6 | |
| GO | GO:0005739 GO:0003985 | |
| Gene3D | 3.40.47.10 | |
| InterPro | IPR002155 IPR016039 IPR016038 IPR020610 IPR020617 IPR020613 IPR020616 | |
| Pfam | PF02803 PF00108 | |
| PIRSF | PIRSF000429 | |
| SUPFAM | SSF53901 | |
| TIGRFAMs | TIGR01930 | |
| PROSITE | PS00737 PS00099 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0045797 |
positive regulation of intestinal cholesterol absorption |
ECO:0000314 |
P |
Fig 4 |
complete | |||||
|
involved_in |
GO:0045797 |
positive regulation of intestinal cholesterol absorption |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006635 |
fatty acid beta-oxidation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG14128 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2136381 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003988 |
acetyl-CoA C-acyltransferase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG13097 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003985 |
acetyl-CoA C-acetyltransferase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
EcoGene:EG11672 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:1359366 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005739 |
mitochondrion |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005730 |
nucleolus |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003985 |
acetyl-CoA C-acetyltransferase activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003985 |
acetyl-CoA C-acetyltransferase activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:1359366 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003824 |
catalytic activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016747 |
transferase activity, transferring acyl groups other than amino-acyl groups |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR002155 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003985 |
acetyl-CoA C-acetyltransferase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016746 |
transferase activity, transferring acyl groups |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Nguyen, TM et al. (2012) Cholesterol esterification by ACAT2 is essential for efficient intestinal cholesterol absorption: evidence from thoracic lymph duct cannulation. J. Lipid Res. 53 95-104 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Pagliarini, DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134 112-23 PubMed GONUTS page
