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MOUSE:TGM1

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Tgm1
Protein Name(s) Protein-glutamine gamma-glutamyltransferase K

Epidermal TGase Transglutaminase K TG(K) TGK TGase K Transglutaminase-1 TGase-1

External Links
UniProt Q9JLF6
EMBL AF186373
BC026422
CCDS CCDS36932.1
RefSeq NP_001155186.1
NP_001155187.1
NP_064368.3
XP_006518871.1
XP_006518872.1
UniGene Mm.41964
ProteinModelPortal Q9JLF6
SMR Q9JLF6
IntAct Q9JLF6
MINT MINT-4137626
PhosphoSite Q9JLF6
MaxQB Q9JLF6
PaxDb Q9JLF6
PRIDE Q9JLF6
Ensembl ENSMUST00000002389
ENSMUST00000168729
ENSMUST00000178034
GeneID 21816
KEGG mmu:21816
UCSC uc007uag.2
CTD 7051
MGI MGI:98730
eggNOG NOG80379
GeneTree ENSGT00760000119108
HOGENOM HOG000231695
HOVERGEN HBG004342
InParanoid Q9JLF6
KO K05619
OrthoDB EOG7WT40M
PhylomeDB Q9JLF6
TreeFam TF324278
NextBio 301220
PRO PR:Q9JLF6
Proteomes UP000000589
Bgee Q9JLF6
CleanEx MM_TGM1
Genevestigator Q9JLF6
GO GO:0005913
GO:0070062
GO:0031224
GO:0046872
GO:0003810
GO:0031424
GO:0009887
GO:0018149
GO:0019538
Gene3D 2.60.40.10
3.90.260.10
InterPro IPR023608
IPR013783
IPR014756
IPR002931
IPR008958
IPR013808
IPR001102
PANTHER PTHR11590
Pfam PF00927
PF01841
PF00868
PIRSF PIRSF000459
SMART SM00460
SUPFAM SSF49309
SSF81296
PROSITE PS00547

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0045787

positive regulation of cell cycle

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P22735

P

Seeded From UniProt

complete

involved_in

GO:0010838

positive regulation of keratinocyte proliferation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:P22735

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045787

positive regulation of cell cycle

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P22735

P

Seeded From UniProt

complete

part_of

GO:0031224

intrinsic component of membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P22735

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0030216

keratinocyte differentiation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P22735

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0018149

peptide cross-linking

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P22735

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0010838

positive regulation of keratinocyte proliferation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P22735

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0009887

animal organ morphogenesis

PMID:10567386[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005913

cell-cell adherens junction

PMID:10567386[1]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003810

protein-glutamine gamma-glutamyltransferase activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P22735

F

Seeded From UniProt

complete

enables

GO:0003810

protein-glutamine gamma-glutamyltransferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008958
InterPro:IPR023608
InterPro:IPR036238

F

Seeded From UniProt

complete

involved_in

GO:0018149

peptide cross-linking

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001102
InterPro:IPR008958
InterPro:IPR013808
InterPro:IPR023608
InterPro:IPR036238

P

Seeded From UniProt

complete

enables

GO:0003810

protein-glutamine gamma-glutamyltransferase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:2.3.2.13

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0019538

protein metabolic process

PMID:10567386[1]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0016746

transferase activity, transferring acyl groups

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0012

F

Seeded From UniProt

complete

involved_in

GO:0031424

keratinization

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0417

P

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ 1.0 1.1 1.2 Hiiragi, T et al. (1999) Transglutaminase type 1 and its cross-linking activity are concentrated at adherens junctions in simple epithelial cells. J. Biol. Chem. 274 34148-54 PubMed GONUTS page