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MOUSE:TCTP
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Tpt1 (synonyms: Trt) | |
| Protein Name(s) | Translationally-controlled tumor protein
TCTP 21 kDa polypeptide p21 p23 | |
| External Links | ||
| UniProt | P63028 | |
| EMBL | X06407 AY186881 AK149695 AK150300 AK150500 AK150858 AK151059 AK151266 AK151375 AK151894 AK152690 AK152808 AK159516 AK159565 AK165736 AK166584 AK167413 AK167936 AK168151 AK169730 BC092381 | |
| CCDS | CCDS36980.1 | |
| PIR | S00775 | |
| RefSeq | NP_033455.1 | |
| UniGene | Mm.297482 | |
| ProteinModelPortal | P63028 | |
| SMR | P63028 | |
| BioGrid | 204334 | |
| IntAct | P63028 | |
| MINT | MINT-4137285 | |
| STRING | 10090.ENSMUSP00000106519 | |
| iPTMnet | P63028 | |
| PhosphoSite | P63028 | |
| SwissPalm | P63028 | |
| REPRODUCTION-2DPAGE | IPI00129685 P63028 | |
| SWISS-2DPAGE | P63028 | |
| EPD | P63028 | |
| MaxQB | P63028 | |
| PaxDb | P63028 | |
| PRIDE | P63028 | |
| TopDownProteomics | P63028 | |
| Ensembl | ENSMUST00000110894 | |
| GeneID | 22070 | |
| KEGG | mmu:22070 | |
| UCSC | uc007uqz.2 | |
| CTD | 7178 | |
| MGI | MGI:104890 | |
| eggNOG | KOG1727 ENOG4111FVP | |
| GeneTree | ENSGT00390000006051 | |
| HOVERGEN | HBG002282 | |
| InParanoid | P63028 | |
| OMA | CAMIEEG | |
| OrthoDB | EOG7SJD61 | |
| PhylomeDB | P63028 | |
| TreeFam | TF300238 | |
| PRO | PR:P63028 | |
| Proteomes | UP000000589 | |
| Bgee | P63028 | |
| CleanEx | MM_TPT1 | |
| ExpressionAtlas | P63028 | |
| Genevisible | P63028 | |
| GO | GO:0005737 GO:0070062 GO:0005615 GO:0005771 GO:0005654 GO:0005634 GO:0005509 GO:0044822 GO:0008134 GO:2000384 GO:1902230 GO:0019827 | |
| Gene3D | 2.170.150.10 | |
| InterPro | IPR011057 IPR011323 IPR018103 IPR018105 | |
| PANTHER | PTHR11991 | |
| Pfam | PF00838 | |
| PRINTS | PR01653 | |
| SUPFAM | SSF51316 | |
| PROSITE | PS01002 PS01003 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0000922 |
spindle pole |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005615 |
extracellular space |
ECO:0007005 |
high throughput direct assay evidence used in manual assertion |
C |
produced_by:(CL:0002548) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:2000384 |
negative regulation of ectoderm development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0019827 |
stem cell population maintenance |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
| GO:0007026 |
negative regulation of microtubule depolymerization |
ECO:0000314 |
P |
According to Figure 2, TCTP knockdown perturbs meiotic maturation with spindle defects. Thus, the original purpose of TCTP is the opposite and would therefore normally prevent the breakdown. |
complete | |||||
|
enables |
GO:0008134 |
transcription factor binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005654 |
nucleoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000241815 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005509 |
calcium ion binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000241815 |
F |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:1902230 |
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005881 |
cytoplasmic microtubule |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005771 |
multivesicular body |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005615 |
extracellular space |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005509 |
calcium ion binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000922 |
spindle pole |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007283 |
spermatogenesis |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:P63029 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Abonnenc, M et al. (2013) Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c. Circ. Res. 113 1138-47 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Johansson, H & Simonsson, S (2010) Core transcription factors, Oct4, Sox2 and Nanog, individually form complexes with nucleophosmin (Npm1) to control embryonic stem (ES) cell fate determination. Aging (Albany NY) 2 815-22 PubMed GONUTS page
- ↑ Jeon, HJ et al. (2016) TCTP regulates spindle microtubule dynamics by stabilizing polar microtubules during mouse oocyte meiosis. Biochim. Biophys. Acta 1863 630-7 PubMed GONUTS page
- ↑ 4.0 4.1 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 5.0 5.1 Amzallag, N et al. (2004) TSAP6 facilitates the secretion of translationally controlled tumor protein/histamine-releasing factor via a nonclassical pathway. J. Biol. Chem. 279 46104-12 PubMed GONUTS page
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