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MOUSE:TBPL2
Contents
Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
Gene Name(s) | Tbpl2 (ECO:0000312 with MGI:MGI:2684058) | |
Protein Name(s) | TATA box-binding protein-like protein 2
TBP-like protein 2 TATA box-binding protein-related factor 3 TBP-related factor 3 | |
External Links | ||
UniProt | Q6SJ95 | |
EMBL | AY457924 BK005773 AL844838 AL844838 BC100305 BC119160 | |
CCDS | CCDS15732.1 | |
RefSeq | NP_001276618.1 NP_951014.1 | |
UniGene | Mm.301625 | |
ProteinModelPortal | Q6SJ95 | |
SMR | Q6SJ95 | |
IntAct | Q6SJ95 | |
PRIDE | Q6SJ95 | |
Ensembl | ENSMUST00000080453 | |
GeneID | 227606 | |
KEGG | mmu:227606 | |
UCSC | uc008iol.1 | |
CTD | 387332 | |
MGI | MGI:2684058 | |
eggNOG | COG2101 | |
GeneTree | ENSGT00410000025389 | |
HOGENOM | HOG000105164 | |
HOVERGEN | HBG044997 | |
InParanoid | Q6SJ95 | |
KO | K03120 | |
OMA | ECCGIVP | |
OrthoDB | EOG7XWPPF | |
PhylomeDB | Q6SJ95 | |
TreeFam | TF300102 | |
NextBio | 378650 | |
PRO | PR:Q6SJ95 | |
Proteomes | UP000000589 | |
Bgee | Q6SJ95 | |
CleanEx | MM_TBPL2 | |
ExpressionAtlas | Q6SJ95 | |
Genevestigator | Q6SJ95 | |
GO | GO:0005737 GO:0005634 GO:0003677 GO:0003700 GO:0006352 GO:0007275 GO:0045892 | |
Gene3D | 3.30.310.10 | |
HAMAP | MF_00408 | |
InterPro | IPR012295 IPR000814 | |
PANTHER | PTHR10126 | |
Pfam | PF00352 | |
PRINTS | PR00686 | |
PROSITE | PS00351 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0005515 |
protein binding |
ECO:0000269 |
F |
Figure 1. Tbp2-deficient females do not ovulate upon hormonal stimulation. Control and Tbp2-deficient 4-6 - wk-old females were induced for superovulation with intraperitoneal injection of PMSG followed by administration of hCG 48 h later. |
complete | |||||
involved_in |
GO:0070898 |
RNA polymerase III preinitiation complex assembly |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000013138 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0008134 |
transcription factor binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003687 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006366 |
transcription by RNA polymerase II |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003687 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005669 |
transcription factor TFIID complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003687 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005667 |
transcription factor complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
CGD:CAL0000189736 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0261793 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0001016 |
RNA polymerase III regulatory region DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000013138 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0000979 |
RNA polymerase II core promoter sequence-specific DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0261793 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0000978 |
RNA polymerase II proximal promoter sequence-specific DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003687 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0000126 |
transcription factor TFIIIB complex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003687 |
C |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0045892 |
negative regulation of transcription, DNA-templated |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
|
Seeded From UniProt |
complete | ||
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003677 |
DNA binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q6SJ96 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005634 |
nucleus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q6SJ96 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006352 |
DNA-templated transcription, initiation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007275 |
multicellular organism development |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Gazdag, E et al. (2009) TBP2 is essential for germ cell development by regulating transcription and chromatin condensation in the oocyte. Genes Dev. 23 2210-23 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 2.9 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 Tanaka, Y et al. (2007) Transcriptional repression of the mouse wee1 gene by TBP-related factor 2. Biochem. Biophys. Res. Commun. 352 21-8 PubMed GONUTS page
- ↑ Gazdag, E et al. (2007) Analysis of TATA-binding protein 2 (TBP2) and TBP expression suggests different roles for the two proteins in regulation of gene expression during oogenesis and early mouse development. Reproduction 134 51-62 PubMed GONUTS page
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- GO:0070898 ! RNA polymerase III preinitiation complex assembly
- GO:0000978 ! RNA polymerase II cis-regulatory region sequence-specific DNA binding
- GO:0000979 ! RNA polymerase II core promoter sequence-specific DNA binding
- GO:0001016 ! RNA polymerase III transcription regulatory region sequence-specific DNA binding
- Rodentia
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