MOUSE:SHAN2

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Shank2 (synonyms: Cortbp1, Kiaa1022)
Protein Name(s)	SH3 and multiple ankyrin repeat domains protein 2 Shank2 Cortactin-binding protein 1 CortBP1
External Links
UniProt	Q80Z38
EMBL	AB099695 AC124520 AC127546 AC140268 AC152166 BC167171 AK139360 AK220363
CCDS	CCDS40201.1
RefSeq	NP_001074839.2 NP_001106844.2 XP_006508596.1
UniGene	Mm.483624
ProteinModelPortal	Q80Z38
SMR	Q80Z38
BioGrid	229144
IntAct	Q80Z38
PhosphoSite	Q80Z38
MaxQB	Q80Z38
PaxDb	Q80Z38
PRIDE	Q80Z38
DNASU	210274
Ensembl	ENSMUST00000097929
GeneID	210274
KEGG	mmu:210274
UCSC	uc009kqe.2 uc009kqf.1 uc009kqg.1
CTD	22941
MGI	MGI:2671987
eggNOG	COG0666
GeneTree	ENSGT00510000046474
HOGENOM	HOG000293276
HOVERGEN	HBG054027
InParanoid	Q80Z38
KO	K15009
NextBio	372912
PRO	PR:Q80Z38
Proteomes	UP000000589
Bgee	Q80Z38
CleanEx	MM_SHANK2
ExpressionAtlas	Q80Z38
Genevestigator	Q80Z38
GO	GO:0016324 GO:0031526 GO:0030054 GO:0060170 GO:0005737 GO:0043197 GO:0030426 GO:0043005 GO:0043025 GO:0001917 GO:0001750 GO:0005886 GO:0014069 GO:0045211 GO:0035255 GO:0030534 GO:0035640 GO:0007612 GO:0060292 GO:0060291 GO:0007613 GO:0035176 GO:0007416 GO:0071625
Gene3D	1.10.150.50 2.30.42.10
InterPro	IPR001478 IPR001660 IPR013761 IPR021129 IPR011511 IPR001452
Pfam	PF00595 PF00536 PF07653
SMART	SM00228 SM00454 SM00326
SUPFAM	SSF47769 SSF50044 SSF50156
PROSITE	PS50106 PS50105 PS50002

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0001750	photoreceptor outer segment	PMID:19299912^[1]	ECO:0000314			C		Shank 2 expression in developing mouse retina figure 1.	complete CACAO 3189
	GO:0001917	photoreceptor inner segment	PMID:19299912^[1]	ECO:0000314			C		Shank 2 expression in developing mouse retina figure 1.	complete CACAO 3190
	GO:0005883	neurofilament	PMID:19299912^[1]	ECO:0000314			C		Shank2 is colocalized with neurofilament which is a neuronal differentiation marker during developing mouse retinal, figure 2.	complete CACAO 3191
	GO:0005886	plasma membrane	PMID:15207857^[2]	ECO:0000314			C		COS7 cells expressed with Glur1, shank 2 localized to membrane figure 1B.	complete CACAO 3206
	GO:0051968	positive regulation of synaptic transmission, glutamatergic	PMID:22699619^[3]	ECO:0000315			P		Figure 2 shows that in Shank2 lacking mutant mice there was reduced synaptic transmission compared to the wild type mice suggesting that Shank2 is a positive regulator of the hippocampal glutamatergic synaptic transmission.	complete CACAO 6195
	GO:0043197	dendritic spine	PMID:15207857^[2]	ECO:0000314			C		Figure 3B and C, immunohistochemical analysis showed Shank2 protein staining on dendritic spines of Purkinje cells	complete CACAO 3207
part_of	GO:0043197	dendritic spine	PMID:15207857^[2]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:15207857^[2]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005883	neurofilament	PMID:19299912^[1]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0001917	photoreceptor inner segment	PMID:19299912^[1]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0001750	photoreceptor outer segment	PMID:19299912^[1]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0051968	positive regulation of synaptic transmission, glutamatergic	PMID:22699619^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0071625	vocalization behavior	PMID:22699620^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0060292	long-term synaptic depression	PMID:22699620^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(UBERON:0003881)	Seeded From UniProt	complete
involved_in	GO:0060291	long-term synaptic potentiation	PMID:22699620^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(UBERON:0003881)	Seeded From UniProt	complete
part_of	GO:0060170	ciliary membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9QX74	C		Seeded From UniProt	complete
colocalizes_with	GO:0045211	postsynaptic membrane	PMID:15207857^[2]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0043197	dendritic spine	PMID:15207857^[2]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0043025	neuronal cell body	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9QX74	C		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	PMID:21795692^[5]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0002608)	Seeded From UniProt	complete
involved_in	GO:0035640	exploration behavior	PMID:22699620^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0035255	ionotropic glutamate receptor binding	PMID:15207857^[2]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q61625	F		Seeded From UniProt	complete
enables	GO:0035255	ionotropic glutamate receptor binding	PMID:16606358^[6]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:P23818	F		Seeded From UniProt	complete
involved_in	GO:0035176	social behavior	PMID:22699620^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0031526	brush border membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9QX74	C		Seeded From UniProt	complete
involved_in	GO:0030534	adult behavior	PMID:22699620^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0030426	growth cone	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9QX74	C		Seeded From UniProt	complete
part_of	GO:0016324	apical plasma membrane	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9QX74	C		Seeded From UniProt	complete
part_of	GO:0014069	postsynaptic density	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9QX74	C		Seeded From UniProt	complete
colocalizes_with	GO:0008328	ionotropic glutamate receptor complex	PMID:15207857^[2]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0007613	memory	PMID:22699620^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007612	learning	PMID:22699620^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007416	synapse assembly	PMID:22699620^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(UBERON:0003881)	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:15207857^[2]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
colocalizes_with	GO:0005883	neurofilament	PMID:19299912^[1]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0001917	photoreceptor inner segment	PMID:19299912^[1]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0001750	photoreceptor outer segment	PMID:19299912^[1]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0099562	maintenance of postsynaptic density structure	PMID:22699620^[4]	ECO:0006042	cell fractionation evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0099562	maintenance of postsynaptic density structure	PMID:22699620^[4]	ECO:0001225	knockout evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0099562	maintenance of postsynaptic density structure	PMID:22699620^[4]	ECO:0000279	western blot evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:2000463	positive regulation of excitatory postsynaptic potential	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 MGI:MGI:3613677 PANTHER:PTN001191880	P		Seeded From UniProt	complete
involved_in	GO:2000311	regulation of AMPA receptor activity	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:3613677 PANTHER:PTN001191880	P		Seeded From UniProt	complete
involved_in	GO:0097107	postsynaptic density assembly	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 PANTHER:PTN001191880	P		Seeded From UniProt	complete
involved_in	GO:0060999	positive regulation of dendritic spine development	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 PANTHER:PTN001191880 RGD:621011	P		Seeded From UniProt	complete
involved_in	GO:0060997	dendritic spine morphogenesis	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 MGI:MGI:3613677 PANTHER:PTN001191880	P		Seeded From UniProt	complete
involved_in	GO:0060291	long-term synaptic potentiation	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 MGI:MGI:2671987 PANTHER:PTN001191880	P		Seeded From UniProt	complete
involved_in	GO:0051968	positive regulation of synaptic transmission, glutamatergic	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 MGI:MGI:2671987 PANTHER:PTN001191880	P		Seeded From UniProt	complete
involved_in	GO:0051124	synaptic growth at neuromuscular junction	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0040752 PANTHER:PTN001191880	P		Seeded From UniProt	complete
involved_in	GO:0048854	brain morphogenesis	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 PANTHER:PTN001191880 ZFIN:ZDB-GENE-060503-369	P		Seeded From UniProt	complete
colocalizes_with	GO:0045211	postsynaptic membrane	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2671987 MGI:MGI:3613677 PANTHER:PTN001191880 RGD:621011	C		Seeded From UniProt	complete
part_of	GO:0044309	neuron spine	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 PANTHER:PTN001191880	C		Seeded From UniProt	complete
part_of	GO:0043197	dendritic spine	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2671987 MGI:MGI:3613677 PANTHER:PTN001191880 RGD:621011	C		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 MGI:MGI:2671987 MGI:MGI:3613677 PANTHER:PTN001191880	C		Seeded From UniProt	complete
enables	GO:0035255	ionotropic glutamate receptor binding	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 MGI:MGI:2671987 MGI:MGI:3613677 PANTHER:PTN001191878 RGD:621011	F		Seeded From UniProt	complete
part_of	GO:0030425	dendrite	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:3613677 PANTHER:PTN001191880	C		Seeded From UniProt	complete
enables	GO:0030160	GKAP/Homer scaffold activity	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:3613677 PANTHER:PTN001191878 RGD:621011 RGD:69264	F		Seeded From UniProt	complete
enables	GO:0030159	receptor signaling complex adaptor activity	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001191878 RGD:621011	F		Seeded From UniProt	complete
part_of	GO:0014069	postsynaptic density	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0040752 MGI:MGI:3613677 PANTHER:PTN001191880 RGD:628772 RGD:69264	C		Seeded From UniProt	complete
colocalizes_with	GO:0008328	ionotropic glutamate receptor complex	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:2671987 MGI:MGI:3613677 PANTHER:PTN001191878	C		Seeded From UniProt	complete
involved_in	GO:0007416	synapse assembly	PMID:21873635^[7]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1930016 MGI:MGI:2671987 PANTHER:PTN001191880	P		Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:628772	C		Seeded From UniProt	complete
enables	GO:0098919	structural constituent of postsynaptic density	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:628772	F		Seeded From UniProt	complete
part_of	GO:0098686	hippocampal mossy fiber to CA3 synapse	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:628772	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0071625	vocalization behavior	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9UPX8	P		Seeded From UniProt	complete
part_of	GO:0060170	ciliary membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:628772	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0050807	regulation of synapse organization	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:628772	P		Seeded From UniProt	complete
part_of	GO:0048786	presynaptic active zone	PMID:21119615^[8]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9QX74	C		Seeded From UniProt	complete
part_of	GO:0043025	neuronal cell body	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:628772	C		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	PMID:26627310^[9]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0035176	social behavior	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9UPX8	P		Seeded From UniProt	complete
part_of	GO:0032279	asymmetric synapse	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:628772	C		Seeded From UniProt	complete
part_of	GO:0031526	brush border membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:628772	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030534	adult behavior	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9UPX8	P		Seeded From UniProt	complete
part_of	GO:0030426	growth cone	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:628772	C		Seeded From UniProt	complete
enables	GO:0017124	SH3 domain binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:628772	F		Seeded From UniProt	complete
part_of	GO:0016324	apical plasma membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:628772	C		Seeded From UniProt	complete
part_of	GO:0014069	postsynaptic density	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:628772	C		Seeded From UniProt	complete
enables	GO:0008022	protein C-terminus binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:628772	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007612	learning	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9UPX8	P		Seeded From UniProt	complete
part_of	GO:0120038	plasma membrane bounded cell projection part	PMID:26627310^[9]	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0017146	NMDA selective glutamate receptor complex	PMID:26627310^[9]	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0042995	cell projection	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0966	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
enables	GO:0017124	SH3 domain binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0729	F		Seeded From UniProt	complete
part_of	GO:0045211	postsynaptic membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0628	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
part_of	GO:0030054	cell junction	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0965	C		Seeded From UniProt	complete
part_of	GO:0045202	synapse	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0770 UniProtKB-SubCell:SL-0258	C		Seeded From UniProt	complete
part_of	GO:0014069	postsynaptic density	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0297	C		Seeded From UniProt	complete
part_of	GO:0016324	apical plasma membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0015	C		Seeded From UniProt	complete
part_of	GO:0043197	dendritic spine	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0284	C		Seeded From UniProt	complete
part_of	GO:0030426	growth cone	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0288	C		Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 ^1.8 Kim, JH et al. (2009) Shank 2 expression coincides with neuronal differentiation in the developing retina. Exp. Mol. Med. 41 236-42 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 ^2.7 ^2.8 Uemura, T et al. (2004) Direct interaction of GluRdelta2 with Shank scaffold proteins in cerebellar Purkinje cells. Mol. Cell. Neurosci. 26 330-41 PubMed GONUTS page
↑ ^3.0 ^3.1 Schmeisser, MJ et al. (2012) Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2. Nature 486 256-60 PubMed GONUTS page
↑ ^4.00 ^4.01 ^4.02 ^4.03 ^4.04 ^4.05 ^4.06 ^4.07 ^4.08 ^4.09 ^4.10 ^4.11 Won, H et al. (2012) Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function. Nature 486 261-5 PubMed GONUTS page
↑ Verpelli, C et al. (2011) Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses. J. Biol. Chem. 286 34839-50 PubMed GONUTS page
↑ Uchino, S et al. (2006) Direct interaction of post-synaptic density-95/Dlg/ZO-1 domain-containing synaptic molecule Shank3 with GluR1 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor. J. Neurochem. 97 1203-14 PubMed GONUTS page
↑ ^7.00 ^7.01 ^7.02 ^7.03 ^7.04 ^7.05 ^7.06 ^7.07 ^7.08 ^7.09 ^7.10 ^7.11 ^7.12 ^7.13 ^7.14 ^7.15 ^7.16 ^7.17 ^7.18 ^7.19 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Yang, J et al. (2011) DGKι regulates presynaptic release during mGluR-dependent LTD. EMBO J. 30 165-80 PubMed GONUTS page
↑ ^9.0 ^9.1 ^9.2 Berg, JM et al. (2015) JAKMIP1, a Novel Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse. Neuron 88 1173-1191 PubMed GONUTS page

[PMID:19299912-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 ^1.8 Kim, JH et al. (2009) Shank 2 expression coincides with neuronal differentiation in the developing retina. Exp. Mol. Med. 41 236-42 PubMed GONUTS page

[PMID:15207857-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 ^2.7 ^2.8 Uemura, T et al. (2004) Direct interaction of GluRdelta2 with Shank scaffold proteins in cerebellar Purkinje cells. Mol. Cell. Neurosci. 26 330-41 PubMed GONUTS page

[PMID:22699619-3] 3.0 ^3.1 Schmeisser, MJ et al. (2012) Autistic-like behaviours and hyperactivity in mice lacking ProSAP1/Shank2. Nature 486 256-60 PubMed GONUTS page

[PMID:22699620-4] 4.00 ^4.01 ^4.02 ^4.03 ^4.04 ^4.05 ^4.06 ^4.07 ^4.08 ^4.09 ^4.10 ^4.11 Won, H et al. (2012) Autistic-like social behaviour in Shank2-mutant mice improved by restoring NMDA receptor function. Nature 486 261-5 PubMed GONUTS page

[PMID:21795692-5] Verpelli, C et al. (2011) Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses. J. Biol. Chem. 286 34839-50 PubMed GONUTS page

[PMID:16606358-6] Uchino, S et al. (2006) Direct interaction of post-synaptic density-95/Dlg/ZO-1 domain-containing synaptic molecule Shank3 with GluR1 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor. J. Neurochem. 97 1203-14 PubMed GONUTS page

[PMID:21873635-7] 7.00 ^7.01 ^7.02 ^7.03 ^7.04 ^7.05 ^7.06 ^7.07 ^7.08 ^7.09 ^7.10 ^7.11 ^7.12 ^7.13 ^7.14 ^7.15 ^7.16 ^7.17 ^7.18 ^7.19 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:21119615-8] Yang, J et al. (2011) DGKι regulates presynaptic release during mGluR-dependent LTD. EMBO J. 30 165-80 PubMed GONUTS page

[PMID:26627310-9] 9.0 ^9.1 ^9.2 Berg, JM et al. (2015) JAKMIP1, a Novel Regulator of Neuronal Translation, Modulates Synaptic Function and Autistic-like Behaviors in Mouse. Neuron 88 1173-1191 PubMed GONUTS page

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

MOUSE:SHAN2

Contents

Annotations

Notes

References

a

b

c

d

e

g

h

i

l

m

n

o

p

r

s

v

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools