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MOUSE:RHDF2
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Rhbdf2 (synonyms: Irhom2, Rhbdl6, Rhor) | |
| Protein Name(s) | Inactive rhomboid protein 2
iRhom2 Rhomboid family member 2 Rhomboid veinlet-like protein 6 Rhomboid-related protein | |
| External Links | ||
| UniProt | Q80WQ6 | |
| EMBL | AY167043 AK028872 AK171085 AL607039 BC031398 BC052182 | |
| CCDS | CCDS25672.1 | |
| RefSeq | NP_001161152.1 NP_766160.2 | |
| UniGene | Mm.89695 | |
| ProteinModelPortal | Q80WQ6 | |
| IntAct | Q80WQ6 | |
| MINT | MINT-8177177 | |
| MEROPS | S54.953 | |
| PhosphoSite | Q80WQ6 | |
| MaxQB | Q80WQ6 | |
| PaxDb | Q80WQ6 | |
| PRIDE | Q80WQ6 | |
| Ensembl | ENSMUST00000103028 ENSMUST00000103029 | |
| GeneID | 217344 | |
| KEGG | mmu:217344 | |
| UCSC | uc007mls.3 | |
| CTD | 79651 | |
| MGI | MGI:2442473 | |
| eggNOG | COG0705 | |
| GeneTree | ENSGT00390000012532 | |
| HOGENOM | HOG000154118 | |
| HOVERGEN | HBG059673 | |
| InParanoid | Q80WQ6 | |
| OMA | QRPRNPA | |
| OrthoDB | EOG7288QH | |
| PhylomeDB | Q80WQ6 | |
| TreeFam | TF312988 | |
| NextBio | 375793 | |
| PRO | PR:Q80WQ6 | |
| Proteomes | UP000000589 | |
| Bgee | Q80WQ6 | |
| Genevestigator | Q80WQ6 | |
| GO | GO:0005789 GO:0016021 GO:0005886 GO:0050709 GO:0015031 GO:0006508 | |
| Gene3D | 1.20.1540.10 | |
| InterPro | IPR002610 IPR022764 IPR022241 | |
| PANTHER | PTHR22936 | |
| Pfam | PF01694 PF12595 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0050709 |
negative regulation of protein secretion |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005789 |
endoplasmic reticulum membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
NOT|enables |
GO:0004252 |
serine-type endopeptidase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0050708 |
regulation of protein secretion |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001117529 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042058 |
regulation of epidermal growth factor receptor signaling pathway |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN001117529 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005789 |
endoplasmic reticulum membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0041723 |
C |
Seeded From UniProt |
complete | ||
|
NOT|enables |
GO:0004252 |
serine-type endopeptidase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:2442473 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q6PJF5 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006508 |
proteolysis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0015031 |
protein transport |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005789 |
endoplasmic reticulum membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Zettl, M et al. (2011) Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signaling. Cell 145 79-91 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
