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MOUSE:Q61953

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Neb (ECO:0000313 with MGI:MGI:97292) (synonyms: nebulin (ECO:0000313 with EMBL:CAA49623.1))
Protein Name(s) Nebulin (ECO:0000313 with EMBL:CAA49623.1)
External Links
UniProt Q61953
EMBL X70032
PIR I48678
RefSeq NP_035019.1
UniGene Mm.389247
GeneID 17996
KEGG mmu:17996
CTD 4703
MGI MGI:97292
KO K18267
ChiTaRS Neb
NextBio 292983
Genevestigator Q61953
GO GO:0043292
GO:0043234
GO:0005865
GO:0030018
GO:0030832
GO:0045214
InterPro IPR013998
IPR000900
Pfam PF00880
PRINTS PR00510
SMART SM00227
PROSITE PS51216

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0071691

cardiac muscle thin filament assembly

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001665296
UniProtKB:O76041

P

Seeded From UniProt

complete

enables

GO:0051015

actin filament binding

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000113268
UniProtKB:O76041

F

Seeded From UniProt

complete

involved_in

GO:0048747

muscle fiber development

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN001665296
ZFIN:ZDB-GENE-041111-216

P

Seeded From UniProt

complete

part_of

GO:0030018

Z disc

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:97292
PANTHER:PTN001665296
UniProtKB:O76041
UniProtKB:P20929

C

Seeded From UniProt

complete

part_of

GO:0043292

contractile fiber

PMID:20368620[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0032991

protein-containing complex

PMID:18468998[3]

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q6P516

C

Seeded From UniProt

complete

part_of

GO:0030018

Z disc

PMID:20368620[2]

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0030018

Z disc

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:P20929

C

Seeded From UniProt

complete

part_of

GO:0030016

myofibril

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:1311134

C

Seeded From UniProt

complete

enables

GO:0003779

actin binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR013998

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045214

sarcomere organization

PMID:8618961[4]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0030832

regulation of actin filament length

PMID:8618961[4]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005865

striated muscle thin filament

PMID:8618961[4]

ECO:0000304

author statement supported by traceable reference used in manual assertion

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 1.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. 2.0 2.1 Gokhin, DS et al. (2010) Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology. J. Cell Biol. 189 95-109 PubMed GONUTS page
  3. Lyssand, JS et al. (2008) Blood pressure is regulated by an alpha1D-adrenergic receptor/dystrophin signalosome. J. Biol. Chem. 283 18792-800 PubMed GONUTS page
  4. 4.0 4.1 4.2 Schiaffino, S & Reggiani, C (1996) Molecular diversity of myofibrillar proteins: gene regulation and functional significance. Physiol. Rev. 76 371-423 PubMed GONUTS page