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MOUSE:Q5SSJ1

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) No Information Provided.
Protein Name(s) Activated macrophage/microglia WAP domain protein (ECO:0000313 with EMBL:ACI01435.1)

OTTMUSG00000000971 protein (ECO:0000313 with EMBL:AAH89618.1) Protein Wfdc17 (ECO:0000313 with Ensembl:ENSMUSP00000090511)

External Links
UniProt Q5SSJ1
EMBL AL663075
BC089618
FJ007372
RefSeq NP_001075426.1
XP_006544523.1
UniGene Mm.24097
SMR Q5SSJ1
STRING 10090.ENSMUSP00000090511
MEROPS I17.004
Ensembl ENSMUST00000092836
GeneID 100034251
102642186
KEGG mmu:100034251
mmu:102642186
UCSC uc007kpq.1
CTD 100034251
MGI MGI:3649773
eggNOG euNOG25663
GeneTree ENSGT00530000064879
HOGENOM HOG000115819
HOVERGEN HBG057975
OMA AEMCSGD
OrthoDB EOG7T1RFD
TreeFam TF338375
NextBio 440470
Proteomes UP000000589
Genevestigator Q5SSJ1
GO GO:0005576
GO:0030414
Gene3D 4.10.75.10
InterPro IPR008197
IPR029716
PANTHER PTHR19441:SF23
Pfam PF00095
PRINTS PR00003
SMART SM00217
SUPFAM SSF57256
PROSITE PS51390

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0004867

serine-type endopeptidase inhibitor activity

PMID:20709948[1]

ECO:0000314

F

Figure 9E: AMWAP attenuates microglial migration and exerts anti-serine protease activity. Quantitative analysis of anti-protease activity in AMWAP-GFP and GFP expressing BV-2 microglia.

complete
CACAO 10071

enables

GO:0004867

serine-type endopeptidase inhibitor activity

PMID:20709948[1]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0008150

biological_process

GO_REF:0000015

ECO:0000307

no biological data found used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005575

cellular_component

GO_REF:0000015

ECO:0000307

no biological data found used in manual assertion

C

Seeded From UniProt

complete

involved_in

GO:0010466

negative regulation of peptidase activity

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0030414

P

Seeded From UniProt

complete

involved_in

GO:0010951

negative regulation of endopeptidase activity

GO_REF:0000108

ECO:0000364

evidence based on logical inference from manual annotation used in automatic assertion

GO:0004867

P

Seeded From UniProt

complete

part_of

GO:0005576

extracellular region

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008197

C

Seeded From UniProt

complete

enables

GO:0030414

peptidase inhibitor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008197

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Karlstetter, M et al. (2010) The novel activated microglia/macrophage WAP domain protein, AMWAP, acts as a counter-regulator of proinflammatory response. J. Immunol. 185 3379-90 PubMed GONUTS page