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MOUSE:PTPS

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Pts
Protein Name(s) 6-pyruvoyl tetrahydrobiopterin synthase

PTP synthase PTPS

External Links
UniProt Q9R1Z7
EMBL AF061880
AF061878
AF061879
AF043225
AK002614
AK146987
BC029013
CCDS CCDS23164.1
RefSeq NP_035350.1
UniGene Mm.35856
ProteinModelPortal Q9R1Z7
SMR Q9R1Z7
IntAct Q9R1Z7
MINT MINT-217930
STRING 10090.ENSMUSP00000034570
PhosphoSite Q9R1Z7
MaxQB Q9R1Z7
PaxDb Q9R1Z7
PRIDE Q9R1Z7
Ensembl ENSMUST00000034570
GeneID 19286
KEGG mmu:19286
UCSC uc009pjp.1
CTD 5805
MGI MGI:1338783
eggNOG COG0720
GeneTree ENSGT00390000002752
HOGENOM HOG000225069
HOVERGEN HBG004358
InParanoid Q9R1Z7
KO K01737
OMA CHRLHSK
OrthoDB EOG7NSB3V
PhylomeDB Q9R1Z7
TreeFam TF105796
Reactome REACT_199047
UniPathway UPA00849
ChiTaRS Pts
NextBio 296210
PRO PR:Q9R1Z7
Proteomes UP000000589
Bgee Q9R1Z7
CleanEx MM_PTS
Genevestigator Q9R1Z7
GO GO:0005739
GO:0003874
GO:0042802
GO:0046872
GO:0042803
GO:0006729
InterPro IPR007115
IPR022470
IPR022469
PANTHER PTHR12589
Pfam PF01242
PIRSF PIRSF006113
TIGRFAMs TIGR00039
PROSITE PS00987
PS00988

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0006729

tetrahydrobiopterin biosynthetic process

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1338783
PANTHER:PTN000287393
WB:WBGene00015010

P

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000287347
UniProtKB:Q03393

C

Seeded From UniProt

complete

enables

GO:0003874

6-pyruvoyltetrahydropterin synthase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

MGI:MGI:1338783
PANTHER:PTN000287393
RGD:68367
WB:WBGene00015010
dictyBase:DDB_G0279095

F

Seeded From UniProt

complete

enables

GO:0042803

protein homodimerization activity

PMID:9894812[2]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q9R1Z7

F

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:11591653[3]

ECO:0000353

physical interaction evidence used in manual assertion

UniProtKB:Q9R1Z7

F

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q03393

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006729

tetrahydrobiopterin biosynthetic process

PMID:9894812[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

PMID:18614015[4]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q03393

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q03393

C

Seeded From UniProt

complete

enables

GO:0003874

6-pyruvoyltetrahydropterin synthase activity

PMID:9894812[2]

ECO:0000314

direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003874

6-pyruvoyltetrahydropterin synthase activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:68367

F

Seeded From UniProt

complete

enables

GO:0003874

6-pyruvoyltetrahydropterin synthase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:P27213
ensembl:ENSRNOP00000012434

F

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q03393
ensembl:ENSP00000280362

F

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q03393
ensembl:ENSP00000280362

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q03393
ensembl:ENSP00000280362

C

Seeded From UniProt

complete

enables

GO:0003874

6-pyruvoyltetrahydropterin synthase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR022469
InterPro:IPR022470

F

Seeded From UniProt

complete

involved_in

GO:0006729

tetrahydrobiopterin biosynthetic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR022469
InterPro:IPR022470

P

Seeded From UniProt

complete

enables

GO:0003874

6-pyruvoyltetrahydropterin synthase activity

GO_REF:0000003

ECO:0000501

evidence used in automatic assertion

EC:4.2.3.12

F

Seeded From UniProt

complete

enables

GO:0016829

lyase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0456

F

Seeded From UniProt

complete

involved_in

GO:0006729

tetrahydrobiopterin biosynthetic process

GO_REF:0000037
GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0783
UniPathway:UPA00849

P

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  2. 2.0 2.1 2.2 Turri, MO et al. (1998) Structure, genomic localization and recombinant expression of the mouse 6-pyruvoyl-tetrahydropterin synthase gene. Biol. Chem. 379 1441-7 PubMed GONUTS page
  3. Suzuki, H et al. (2001) Protein-protein interaction panel using mouse full-length cDNAs. Genome Res. 11 1758-65 PubMed GONUTS page
  4. Pagliarini, DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134 112-23 PubMed GONUTS page