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MOUSE:PTPRE
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Ptpre (synonyms: Ptpe) | |
| Protein Name(s) | Receptor-type tyrosine-protein phosphatase epsilon
Protein-tyrosine phosphatase epsilon R-PTP-epsilon | |
| External Links | ||
| UniProt | P49446 | |
| EMBL | U35368 U36758 U40280 D83484 U62387 AK154910 CH466531 CH466531 Z23052 Z23053 | |
| CCDS | CCDS21944.1 | |
| PIR | B61180 JC6132 S40284 | |
| RefSeq | NP_035342.3 XP_006507522.1 XP_006507523.1 XP_006507524.1 | |
| UniGene | Mm.945 | |
| ProteinModelPortal | P49446 | |
| SMR | P49446 | |
| BioGrid | 202496 | |
| IntAct | P49446 | |
| PhosphoSite | P49446 | |
| MaxQB | P49446 | |
| PaxDb | P49446 | |
| PRIDE | P49446 | |
| DNASU | 19267 | |
| Ensembl | ENSMUST00000073961 | |
| GeneID | 19267 | |
| KEGG | mmu:19267 | |
| UCSC | uc009kee.1 uc009kek.1 | |
| CTD | 5791 | |
| MGI | MGI:97813 | |
| eggNOG | COG5599 | |
| GeneTree | ENSGT00760000118900 | |
| HOVERGEN | HBG053758 | |
| InParanoid | P49446 | |
| KO | K18033 | |
| OMA | IVIDAMI | |
| OrthoDB | EOG7B31M8 | |
| PhylomeDB | P49446 | |
| TreeFam | TF351829 | |
| ChiTaRS | Ptpre | |
| NextBio | 296146 | |
| PRO | PR:P49446 | |
| Proteomes | UP000000589 | |
| Bgee | P49446 | |
| CleanEx | MM_PTPRE | |
| Genevestigator | P49446 | |
| GO | GO:0005737 GO:0016021 GO:0005634 GO:0005886 GO:0042803 GO:0004725 GO:0046627 GO:0035335 GO:0033003 GO:0007185 | |
| Gene3D | 3.90.190.10 | |
| InterPro | IPR029021 IPR000387 IPR016130 IPR000242 IPR016336 | |
| Pfam | PF00102 | |
| PIRSF | PIRSF002006 | |
| PRINTS | PR00700 | |
| SMART | SM00194 | |
| SUPFAM | SSF52799 | |
| PROSITE | PS00383 PS50056 PS50055 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0046627 |
negative regulation of insulin receptor signaling pathway |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0033003 |
regulation of mast cell activation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0046627 |
negative regulation of insulin receptor signaling pathway |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:620771 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0042803 |
protein homodimerization activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0007185 |
transmembrane receptor protein tyrosine phosphatase signaling pathway |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004725 |
protein tyrosine phosphatase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0035335 |
peptidyl-tyrosine dephosphorylation |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004725 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0035335 |
peptidyl-tyrosine dephosphorylation |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0004725 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0035335 |
peptidyl-tyrosine dephosphorylation |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0004725 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0004725 |
protein tyrosine phosphatase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0006470 |
protein dephosphorylation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0016311 |
dephosphorylation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016791 |
phosphatase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004725 |
protein tyrosine phosphatase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0004721 |
phosphoprotein phosphatase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Aga-Mizrachi, S et al. (2008) Cytosolic protein tyrosine phosphatase-epsilon is a negative regulator of insulin signaling in skeletal muscle. Endocrinology 149 605-14 PubMed GONUTS page
- ↑ Akimoto, M et al. (2009) Protein tyrosine phosphatase epsilon is a negative regulator of FcepsilonRI-mediated mast cell responses. Scand. J. Immunol. 69 401-11 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Toledano-Katchalski, H et al. (2003) Dimerization in vivo and inhibition of the nonreceptor form of protein tyrosine phosphatase epsilon. Mol. Cell. Biol. 23 5460-71 PubMed GONUTS page
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