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MOUSE:PMEL
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Pmel (synonyms: D10H12S53E, Pmel17, Si, Silv) | |
| Protein Name(s) | Melanocyte protein PMEL
Melanocyte protein Pmel 17 Premelanosome protein Silver locus protein M-alpha M-beta | |
| External Links | ||
| UniProt | Q60696 | |
| EMBL | U14133 | |
| PIR | S53871 | |
| UniGene | Mm.16756 | |
| ProteinModelPortal | Q60696 | |
| SMR | Q60696 | |
| PhosphoSite | Q60696 | |
| PRIDE | Q60696 | |
| MGI | MGI:98301 | |
| eggNOG | NOG39434 | |
| HOVERGEN | HBG099694 | |
| InParanoid | Q60696 | |
| PhylomeDB | Q60696 | |
| ChiTaRS | Pmel | |
| PRO | PR:Q60696 | |
| Proteomes | UP000000589 | |
| CleanEx | MM_SI | |
| Genevestigator | Q60696 | |
| GO | GO:0005789 GO:0005576 GO:0005794 GO:0016021 GO:0042470 GO:0005771 GO:0042438 | |
| Gene3D | 2.60.40.670 | |
| InterPro | IPR022409 IPR000601 | |
| Pfam | PF00801 | |
| SMART | SM00089 | |
| SUPFAM | SSF49299 | |
| PROSITE | PS50093 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0048023 |
positive regulation of melanin biosynthetic process |
ECO:0000315 |
P |
Based on results in Table 1 |
complete | |||||
|
involved_in |
GO:0048023 |
positive regulation of melanin biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042470 |
melanosome |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:98301 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0032438 |
melanosome organization |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000221144 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1934765 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042470 |
melanosome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042470 |
melanosome |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0042438 |
melanin biosynthetic process |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1857040 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0032585 |
multivesicular body membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0032438 |
melanosome organization |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005789 |
endoplasmic reticulum membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005768 |
endosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042438 |
melanin biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005789 |
endoplasmic reticulum membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042470 |
melanosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005771 |
multivesicular body |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Hellström, AR et al. (2011) Inactivation of Pmel alters melanosome shape but has only a subtle effect on visible pigmentation. PLoS Genet. 7 e1002285 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Hume, AN et al. (2001) Rab27a regulates the peripheral distribution of melanosomes in melanocytes. J. Cell Biol. 152 795-808 PubMed GONUTS page
- ↑ Ozeki, H et al. (1995) Chemical characterization of hair melanins in various coat-color mutants of mice. J. Invest. Dermatol. 105 361-6 PubMed GONUTS page
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