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MOUSE:PDIA4
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Pdia4 (synonyms: Cai, Erp72) | |
| Protein Name(s) | Protein disulfide-isomerase A4
Endoplasmic reticulum resident protein 72 ER protein 72 ERp-72 ERp72 | |
| External Links | ||
| UniProt | P08003 | |
| EMBL | J05186 AK028292 AK146288 AK150566 AK161534 AK169387 BC066857 BC141078 Y00884 | |
| PIR | B34930 S06318 | |
| RefSeq | NP_033917.2 | |
| UniGene | Mm.2442 | |
| PDB | 2DJ1 2DJ2 2DJ3 | |
| PDBsum | 2DJ1 2DJ2 2DJ3 | |
| ProteinModelPortal | P08003 | |
| SMR | P08003 | |
| BioGrid | 198446 | |
| IntAct | P08003 | |
| MINT | MINT-4106888 | |
| PhosphoSite | P08003 | |
| MaxQB | P08003 | |
| PaxDb | P08003 | |
| PRIDE | P08003 | |
| Ensembl | ENSMUST00000077290 | |
| GeneID | 12304 | |
| KEGG | mmu:12304 | |
| UCSC | uc009btf.1 | |
| CTD | 9601 | |
| MGI | MGI:104864 | |
| eggNOG | COG0526 | |
| GeneTree | ENSGT00760000119201 | |
| HOGENOM | HOG000162459 | |
| HOVERGEN | HBG005920 | |
| InParanoid | P08003 | |
| KO | K09582 | |
| OrthoDB | EOG7VHSX1 | |
| PhylomeDB | P08003 | |
| TreeFam | TF106382 | |
| ChiTaRS | Pdia4 | |
| EvolutionaryTrace | P08003 | |
| NextBio | 280830 | |
| PRO | PR:P08003 | |
| Proteomes | UP000000589 | |
| Bgee | P08003 | |
| CleanEx | MM_PDIA4 | |
| Genevestigator | P08003 | |
| GO | GO:0009986 GO:0005783 GO:0005788 GO:0042470 GO:0044822 GO:0003756 GO:0045454 GO:0061077 GO:0006457 GO:0034976 | |
| Gene3D | 3.40.30.10 | |
| InterPro | IPR005788 IPR005792 IPR017068 IPR012336 IPR017937 IPR013766 | |
| Pfam | PF00085 | |
| PIRSF | PIRSF036862 | |
| SUPFAM | SSF52833 | |
| TIGRFAMs | TIGR01130 TIGR01126 | |
| PROSITE | PS00014 PS00194 PS51352 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
part_of |
GO:0034663 |
endoplasmic reticulum chaperone complex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0061077 |
chaperone-mediated protein folding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003756 |
protein disulfide isomerase activity |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0034976 |
response to endoplasmic reticulum stress |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000432607 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0009986 |
cell surface |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:104864 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006457 |
protein folding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000432607 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0014002 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003756 |
protein disulfide isomerase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1919080 |
F |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:1903334 |
positive regulation of protein folding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:619835 |
P |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0061077 |
chaperone-mediated protein folding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:619835 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0015037 |
peptide disulfide oxidoreductase activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0009986 |
cell surface |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0009986 |
cell surface |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005790 |
smooth endoplasmic reticulum |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:619835 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005615 |
extracellular space |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003756 |
protein disulfide isomerase activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:619835 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0055114 |
oxidation-reduction process |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0015037 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003756 |
protein disulfide isomerase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005788 |
endoplasmic reticulum lumen |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016853 |
isomerase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045454 |
cell redox homeostasis |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003756 |
protein disulfide isomerase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005783 |
endoplasmic reticulum |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016853 |
isomerase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005788 |
endoplasmic reticulum lumen |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042470 |
melanosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Meunier, L et al. (2002) A subset of chaperones and folding enzymes form multiprotein complexes in endoplasmic reticulum to bind nascent proteins. Mol. Biol. Cell 13 4456-69 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Holbrook, LM et al. (2010) Platelets release novel thiol isomerase enzymes which are recruited to the cell surface following activation. Br. J. Haematol. 148 627-37 PubMed GONUTS page
- ↑ Miyaishi, O et al. (1998) Elevated expression of PDI family proteins during differentiation of mouse F9 teratocarcinoma cells. J. Cell. Biochem. 68 436-45 PubMed GONUTS page
- ↑ Liegel, RP et al. (2013) Loss-of-function mutations in TBC1D20 cause cataracts and male infertility in blind sterile mice and Warburg micro syndrome in humans. Am. J. Hum. Genet. 93 1001-14 PubMed GONUTS page
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