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MOUSE:MFS12

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Mfsd12
Protein Name(s) Major facilitator superfamily domain-containing protein 12
External Links
UniProt Q3U481
EMBL AK149678
AK154386
AK154902
AK171084
BC118620
BC119790
CCDS CCDS35996.1
RefSeq NP_082933.2
UniGene Mm.182281
ProteinModelPortal Q3U481
STRING 10090.ENSMUSP00000036116
iPTMnet Q3U481
PhosphoSitePlus Q3U481
PaxDb Q3U481
PRIDE Q3U481
DNASU 73822
Ensembl ENSMUST00000044844
GeneID 73822
KEGG mmu:73822
UCSC uc007gho.1
CTD 126321
MGI MGI:3604804
eggNOG ENOG410IMQF
ENOG4111I58
GeneTree ENSGT00390000016464
HOGENOM HOG000006540
HOVERGEN HBG056517
InParanoid Q3U481
OMA VTNDHEK
OrthoDB EOG091G0GHZ
PhylomeDB Q3U481
TreeFam TF314080
PRO PR:Q3U481
Proteomes UP000000589
Bgee ENSMUSG00000034854
CleanEx MM_F630110N24RIK
ExpressionAtlas Q3U481
Genevisible Q3U481
GO GO:0016021
CDD cd06174
InterPro IPR020846
IPR036259
SUPFAM SSF103473

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0048022

negative regulation of melanin biosynthetic process

PMID:29025994[1]

ECO:0000315

P

fig 6 a-d shows that when Mus Musculus MFSD12 is knocked down by shRNA it increases melanin content

complete
CACAO 13088

involved_in

GO:0071702

organic substance transport

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10578
MGI:MGI:1923824
MGI:MGI:3583946
PANTHER:PTN000140373
UniProtKB:A6NFX1
UniProtKB:Q8NA29
ZFIN:ZDB-GENE-040801-89
ZFIN:ZDB-GENE-041114-166

P

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10578
MGI:MGI:1923824
MGI:MGI:3583946
PANTHER:PTN000140373
UniProtKB:A6NFX1

C

Seeded From UniProt

complete

enables

GO:0005215

transporter activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10578
EcoGene:EG11658
EcoGene:EG11841
MGI:MGI:1923824
MGI:MGI:3583946
PANTHER:PTN000140373
UniProtKB:A6NFX1
UniProtKB:Q8NA29

F

Seeded From UniProt

complete

involved_in

GO:0055085

transmembrane transport

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0015293

P

Seeded From UniProt

complete

involved_in

GO:0008643

carbohydrate transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039672

P

Seeded From UniProt

complete

enables

GO:0015293

symporter activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039672

F

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039672

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Crawford, NG et al. (2017) Loci associated with skin pigmentation identified in African populations. Science 358 PubMed GONUTS page
  2. 2.0 2.1 2.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page