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MOUSE:MFS12

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Mfsd12
Protein Name(s) Major facilitator superfamily domain-containing protein 12
External Links
UniProt Q3U481
EMBL AK149678
AK154386
AK154902
AK171084
BC118620
BC119790
CCDS CCDS35996.1
RefSeq NP_082933.2
UniGene Mm.182281
ProteinModelPortal Q3U481
STRING 10090.ENSMUSP00000036116
iPTMnet Q3U481
PhosphoSitePlus Q3U481
PaxDb Q3U481
PRIDE Q3U481
DNASU 73822
Ensembl ENSMUST00000044844
GeneID 73822
KEGG mmu:73822
UCSC uc007gho.1
CTD 126321
MGI MGI:3604804
eggNOG ENOG410IMQF
ENOG4111I58
GeneTree ENSGT00390000016464
HOGENOM HOG000006540
HOVERGEN HBG056517
InParanoid Q3U481
OMA VTNDHEK
OrthoDB EOG091G0GHZ
PhylomeDB Q3U481
TreeFam TF314080
PRO PR:Q3U481
Proteomes UP000000589
Bgee ENSMUSG00000034854
CleanEx MM_F630110N24RIK
ExpressionAtlas Q3U481
Genevisible Q3U481
GO GO:0016021
CDD cd06174
InterPro IPR020846
IPR036259
SUPFAM SSF103473

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0048022

negative regulation of melanin biosynthetic process

PMID:29025994[1]

ECO:0000315

P

fig 6 a-d shows that when Mus Musculus MFSD12 is knocked down by shRNA it increases melanin content

complete
CACAO 13088

involved_in

GO:0071702

organic substance transport

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10578
MGI:MGI:1923824
MGI:MGI:3583946
PANTHER:PTN000140373
UniProtKB:A6NFX1
UniProtKB:Q8NA29
ZFIN:ZDB-GENE-040801-89
ZFIN:ZDB-GENE-041114-166

P

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10578
MGI:MGI:1923824
MGI:MGI:3583946
PANTHER:PTN000140373
UniProtKB:A6NFX1

C

Seeded From UniProt

complete

enables

GO:0005215

transporter activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10578
EcoGene:EG11658
EcoGene:EG11841
MGI:MGI:1923824
MGI:MGI:3583946
PANTHER:PTN000140373
UniProtKB:A6NFX1
UniProtKB:Q8NA29

F

Seeded From UniProt

complete

involved_in

GO:0055085

transmembrane transport

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0015293

P

Seeded From UniProt

complete

involved_in

GO:0008643

carbohydrate transport

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039672

P

Seeded From UniProt

complete

enables

GO:0015293

symporter activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039672

F

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039672

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472
UniProtKB-SubCell:SL-0162

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ Crawford, NG et al. (2017) Loci associated with skin pigmentation identified in African populations. Science 358 PubMed GONUTS page
  2. ↑ 2.0 2.1 2.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page