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MOUSE:MARCS
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Marcks (synonyms: Macs) | |
| Protein Name(s) | Myristoylated alanine-rich C-kinase substrate
MARCKS | |
| External Links | ||
| UniProt | P26645 | |
| EMBL | M60474 BC046601 | |
| CCDS | CCDS23784.1 | |
| PIR | A39169 | |
| RefSeq | NP_032564.1 | |
| UniGene | Mm.30059 | |
| PDB | 1IWQ | |
| PDBsum | 1IWQ | |
| DisProt | DP00253 | |
| ProteinModelPortal | P26645 | |
| BioGrid | 201268 | |
| IntAct | P26645 | |
| MINT | MINT-4101028 | |
| STRING | 10090.ENSMUSP00000090245 | |
| PhosphoSite | P26645 | |
| MaxQB | P26645 | |
| PaxDb | P26645 | |
| PRIDE | P26645 | |
| Ensembl | ENSMUST00000092584 | |
| GeneID | 17118 | |
| KEGG | mmu:17118 | |
| UCSC | uc007evg.1 | |
| CTD | 4082 | |
| MGI | MGI:96907 | |
| eggNOG | NOG44640 | |
| GeneTree | ENSGT00730000111419 | |
| HOGENOM | HOG000113482 | |
| InParanoid | P26645 | |
| KO | K12561 | |
| OMA | SKPENDA | |
| OrthoDB | EOG7P2XW3 | |
| TreeFam | TF332815 | |
| Reactome | REACT_247495 | |
| ChiTaRS | Marcks | |
| EvolutionaryTrace | P26645 | |
| NextBio | 291280 | |
| PRO | PR:P26645 | |
| Proteomes | UP000000589 | |
| Bgee | P26645 | |
| ExpressionAtlas | P26645 | |
| Genevestigator | P26645 | |
| GO | GO:0005938 GO:0005813 GO:0005737 GO:0070062 GO:0042585 GO:0016020 GO:0005080 | |
| InterPro | IPR002101 | |
| PANTHER | PTHR14353 | |
| Pfam | PF02063 | |
| PRINTS | PR00963 | |
| PROSITE | PS00826 PS00827 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0051260 |
protein homooligomerization |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005516 |
calmodulin binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005516 |
calmodulin binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0051015 |
actin filament binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0032432 |
actin filament bundle |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0051764 |
actin crosslink formation |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0051017 |
actin filament bundle assembly |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005080 |
protein kinase C binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042585 |
germinal vesicle |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(CL:0000023) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0016020 |
membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005938 |
cell cortex |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(CL:0000023)|part_of:(CL:0000365) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005813 |
centrosome |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(CL:0000023) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
part_of:(CL:0000023) |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005516 |
calmodulin binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005856 |
cytoskeleton |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005516 |
calmodulin binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003779 |
actin binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Tapp, H et al. (2005) MARCKS is a natively unfolded protein with an inaccessible actin-binding site: evidence for long-range intramolecular interactions. J. Biol. Chem. 280 9946-56 PubMed GONUTS page
- ↑ Izumi, Y et al. (1998) A metalloprotease-disintegrin, MDC9/meltrin-gamma/ADAM9 and PKCdelta are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor. EMBO J. 17 7260-72 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Michaut, MA et al. (2005) Phosphorylated MARCKS: a novel centrosome component that also defines a peripheral subdomain of the cortical actin cap in mouse eggs. Dev. Biol. 280 26-37 PubMed GONUTS page
- ↑ Scarlett, CO & Blackshear, PJ (2003) Neuroanatomical development in the absence of PKC phosphorylation of the myristoylated alanine-rich C-kinase substrate (MARCKS) protein. Brain Res. Dev. Brain Res. 144 25-42 PubMed GONUTS page
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