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MOUSE:LAX1
Contents
Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
Gene Name(s) | Lax1 (synonyms: Lax) | |
Protein Name(s) | Lymphocyte transmembrane adapter 1
Linker for activation of X cells Membrane-associated adapter protein LAX | |
External Links | ||
UniProt | Q8BHB3 | |
EMBL | AY090785 AK040834 AK088503 BC042765 | |
CCDS | CCDS35711.1 | |
RefSeq | NP_001153121.1 NP_766430.3 XP_006529620.1 | |
UniGene | Mm.36534 | |
ProteinModelPortal | Q8BHB3 | |
PhosphoSite | Q8BHB3 | |
PaxDb | Q8BHB3 | |
PRIDE | Q8BHB3 | |
Ensembl | ENSMUST00000169295 | |
GeneID | 240754 | |
KEGG | mmu:240754 | |
UCSC | uc007cqs.2 | |
CTD | 54900 | |
MGI | MGI:2443362 | |
eggNOG | NOG43404 | |
GeneTree | ENSGT00390000014063 | |
HOGENOM | HOG000113286 | |
HOVERGEN | HBG081892 | |
InParanoid | Q8BHB3 | |
OMA | TSNDYVN | |
OrthoDB | EOG76QFHV | |
PhylomeDB | Q8BHB3 | |
TreeFam | TF337411 | |
NextBio | 384719 | |
PRO | PR:Q8BHB3 | |
Proteomes | UP000000589 | |
Bgee | Q8BHB3 | |
CleanEx | MM_LAX1 | |
Genevestigator | Q8BHB3 | |
GO | GO:0005794 GO:0016021 GO:0005886 GO:0050851 GO:0042113 GO:0006955 GO:0048305 GO:0000188 GO:0035556 GO:0046649 GO:0050868 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
acts_upstream_of_or_within |
GO:0050868 |
negative regulation of T cell activation |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0050851 |
antigen receptor-mediated signaling pathway |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3579135 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0048305 |
immunoglobulin secretion |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3579135 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0046649 |
lymphocyte activation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:3579135 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0042169 |
SH2 domain binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0042113 |
B cell activation |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0035556 |
intracellular signal transduction |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0019901 |
protein kinase binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0006955 |
immune response |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005829 |
cytosol |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0000188 |
inactivation of MAPK activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0050868 |
negative regulation of T cell activation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q8IWV1 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0042169 |
SH2 domain binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q8IWV1 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0042113 |
B cell activation |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q8IWV1 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0035556 |
intracellular signal transduction |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q8IWV1 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0019901 |
protein kinase binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q8IWV1 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q8IWV1 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006955 |
immune response |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q8IWV1 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q8IWV1 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005829 |
cytosol |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q8IWV1 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q8IWV1 |
C |
Seeded From UniProt |
complete | ||
involved_in |
GO:0000188 |
inactivation of MAPK activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q8IWV1 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006955 |
immune response |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0051249 |
regulation of lymphocyte activation |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005886 |
plasma membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0002376 |
immune system process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0002250 |
adaptive immune response |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Zhu, M et al. (2005) Negative regulation of lymphocyte activation by the adaptor protein LAX. J. Immunol. 174 5612-9 PubMed GONUTS page