MOUSE:LAX1

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Lax1 (synonyms: Lax)
Protein Name(s)	Lymphocyte transmembrane adapter 1 Linker for activation of X cells Membrane-associated adapter protein LAX
External Links
UniProt	Q8BHB3
EMBL	AY090785 AK040834 AK088503 BC042765
CCDS	CCDS35711.1
RefSeq	NP_001153121.1 NP_766430.3 XP_006529620.1
UniGene	Mm.36534
ProteinModelPortal	Q8BHB3
PhosphoSite	Q8BHB3
PaxDb	Q8BHB3
PRIDE	Q8BHB3
Ensembl	ENSMUST00000169295
GeneID	240754
KEGG	mmu:240754
UCSC	uc007cqs.2
CTD	54900
MGI	MGI:2443362
eggNOG	NOG43404
GeneTree	ENSGT00390000014063
HOGENOM	HOG000113286
HOVERGEN	HBG081892
InParanoid	Q8BHB3
OMA	TSNDYVN
OrthoDB	EOG76QFHV
PhylomeDB	Q8BHB3
TreeFam	TF337411
NextBio	384719
PRO	PR:Q8BHB3
Proteomes	UP000000589
Bgee	Q8BHB3
CleanEx	MM_LAX1
Genevestigator	Q8BHB3
GO	GO:0005794 GO:0016021 GO:0005886 GO:0050851 GO:0042113 GO:0006955 GO:0048305 GO:0000188 GO:0035556 GO:0046649 GO:0050868

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
acts_upstream_of_or_within	GO:0050868	negative regulation of T cell activation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q8IWV1	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0050851	antigen receptor-mediated signaling pathway	PMID:15843560	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3579135	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048305	immunoglobulin secretion	PMID:15843560	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3579135	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0046649	lymphocyte activation	PMID:15843560	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3579135	P		Seeded From UniProt	complete
enables	GO:0042169	SH2 domain binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q8IWV1	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0042113	B cell activation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q8IWV1	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0035556	intracellular signal transduction	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q8IWV1	P		Seeded From UniProt	complete
enables	GO:0019901	protein kinase binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q8IWV1	F		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q8IWV1	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006955	immune response	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q8IWV1	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q8IWV1	C		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q8IWV1	C		Seeded From UniProt	complete
part_of	GO:0005794	Golgi apparatus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q8IWV1	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0000188	inactivation of MAPK activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q8IWV1	P		Seeded From UniProt	complete
involved_in	GO:0050868	negative regulation of T cell activation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8IWV1 ensembl:ENSP00000406970	P		Seeded From UniProt	complete
enables	GO:0042169	SH2 domain binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8IWV1 ensembl:ENSP00000406970	F		Seeded From UniProt	complete
involved_in	GO:0042113	B cell activation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8IWV1 ensembl:ENSP00000406970	P		Seeded From UniProt	complete
involved_in	GO:0035556	intracellular signal transduction	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8IWV1 ensembl:ENSP00000406970	P		Seeded From UniProt	complete
enables	GO:0019901	protein kinase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8IWV1 ensembl:ENSP00000406970	F		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8IWV1 ensembl:ENSP00000406970	C		Seeded From UniProt	complete
involved_in	GO:0006955	immune response	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8IWV1 ensembl:ENSP00000406970	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8IWV1 ensembl:ENSP00000406970	C		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8IWV1 ensembl:ENSP00000406970	C		Seeded From UniProt	complete
part_of	GO:0005794	Golgi apparatus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8IWV1 ensembl:ENSP00000406970	C		Seeded From UniProt	complete
involved_in	GO:0000188	inactivation of MAPK activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q8IWV1 ensembl:ENSP00000406970	P		Seeded From UniProt	complete
involved_in	GO:0006955	immune response	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR031393	P		Seeded From UniProt	complete
involved_in	GO:0051249	regulation of lymphocyte activation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR031393	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
involved_in	GO:0002376	immune system process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0391	P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
involved_in	GO:0002250	adaptive immune response	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1064	P		Seeded From UniProt	complete
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References

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