GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.

Have any questions? Please email us at ecoliwiki@gmail.com

MOUSE:IKBB

From GONUTS
Jump to: navigation, search
Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Nfkbib (synonyms: Ikbb)
Protein Name(s) NF-kappa-B inhibitor beta

NF-kappa-BIB I-kappa-B-beta IkB-B IkB-beta IkappaBbeta

External Links
UniProt Q60778
EMBL U19799
AK010218
AK038631
AK156731
CH466593
CH466593
CCDS CCDS21054.1
RefSeq NP_035038.2
XP_006539676.1
UniGene Mm.220333
PDB 1K3Z
1OY3
PDBsum 1K3Z
1OY3
ProteinModelPortal Q60778
SMR Q60778
BioGrid 201754
DIP DIP-37418N
IntAct Q60778
MINT MINT-1523907
PhosphoSite Q60778
MaxQB Q60778
PaxDb Q60778
PRIDE Q60778
Ensembl ENSMUST00000032815
ENSMUST00000085851
GeneID 18036
KEGG mmu:18036
UCSC uc009fzr.1
CTD 4793
MGI MGI:104752
eggNOG COG0666
GeneTree ENSGT00550000074527
HOGENOM HOG000137336
HOVERGEN HBG019039
InParanoid Q60778
KO K02581
OMA DEWCDSG
OrthoDB EOG7W154S
TreeFam TF320166
Reactome REACT_199121
REACT_202898
REACT_219800
REACT_222971
EvolutionaryTrace Q60778
NextBio 293133
PRO PR:Q60778
Proteomes UP000000589
Bgee Q60778
ExpressionAtlas Q60778
Genevestigator Q60778
GO GO:0005737
GO:0005634
GO:0071222
Gene3D 1.25.40.20
InterPro IPR002110
IPR020683
Pfam PF00023
PRINTS PR01415
SMART SM00248
SUPFAM SSF48403
PROSITE PS50297
PS50088

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0006916

anti-apoptosis

PMID:22223647[1]

ECO:0000315

P

Fig. 5

complete

acts_upstream_of_or_within

GO:0071222

cellular response to lipopolysaccharide

PMID:20060382[2]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007253

cytoplasmic sequestering of NF-kappaB

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:621887

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0007165

signal transduction

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:621887

P

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:621887

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

RGD:621887

C

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Wright, CJ et al. (2012) Nuclear factor-κB (NF-κB) inhibitory protein IκBβ determines apoptotic cell death following exposure to oxidative stress. J. Biol. Chem. 287 6230-9 PubMed GONUTS page
  2. Gu, H et al. (2010) Angiopoietin-1/Tie2 signaling pathway inhibits lipopolysaccharide-induced activation of RAW264.7 macrophage cells. Biochem. Biophys. Res. Commun. 392 178-82 PubMed GONUTS page