MOUSE:ID1

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Id1 (synonyms: Id, Id-1, Idb1)
Protein Name(s)	DNA-binding protein inhibitor ID-1 Inhibitor of DNA binding 1 Inhibitor of differentiation 1
External Links
UniProt	P20067
EMBL	M31885 U43884 AK008264
CCDS	CCDS16897.1
PIR	A34690 S72171
UniGene	Mm.444
ProteinModelPortal	P20067
SMR	P20067
IntAct	P20067
MINT	MINT-217824
STRING	10090.ENSMUSP00000092019
PhosphoSite	P20067
MaxQB	P20067
PaxDb	P20067
PRIDE	P20067
Ensembl	ENSMUST00000038368
MGI	MGI:96396
eggNOG	ENOG410IWDR ENOG4111VAY
HOGENOM	HOG000234788
HOVERGEN	HBG009009
InParanoid	P20067
OrthoDB	EOG7X9G8G
PhylomeDB	P20067
TreeFam	TF326217
Reactome	R-MMU-2559585
PRO	PR:P20067
Proteomes	UP000000589
Bgee	P20067
CleanEx	MM_ID1
ExpressionAtlas	P20067
Genevisible	P20067
GO	GO:0005813 GO:0005737 GO:0005794 GO:0005654 GO:0005634 GO:0003700 GO:0030509 GO:0007420 GO:0036164 GO:1903351 GO:0071364 GO:1990090 GO:1901653 GO:0071560 GO:0007623 GO:0032963 GO:0001886 GO:0007507 GO:0060425 GO:0060426 GO:0043066 GO:0050774 GO:0043392 GO:0045602 GO:0045668 GO:0032091 GO:1903026 GO:0043433 GO:0000122 GO:0045892 GO:0030182 GO:0032233 GO:0050679 GO:0010628 GO:0031648 GO:0045765 GO:0043408 GO:0046677 GO:0006351
Gene3D	4.10.280.10
InterPro	IPR011598 IPR026052
PANTHER	PTHR11723
Pfam	PF00010
SMART	SM00353
SUPFAM	SSF47459
PROSITE	PS50888

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0120163	negative regulation of cold-induced thermogenesis	PMID:28270523^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0007623	circadian rhythm	PMID:19217292^[2]	ECO:0000270	expression pattern evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	PMID:19217292^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006351	transcription, DNA-templated	PMID:17681138^[3]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	PMID:17681138^[3]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0051726	regulation of cell cycle	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000919548 RGD:2860	P		Seeded From UniProt	complete
involved_in	GO:0045665	negative regulation of neuron differentiation	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96397 MGI:MGI:99414 PANTHER:PTN000919548 UniProtKB:O73933 UniProtKB:Q90X14 UniProtKB:Q90X15	P		Seeded From UniProt	complete
involved_in	GO:0043392	negative regulation of DNA binding	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0000575 MGI:MGI:96396 MGI:MGI:96397 PANTHER:PTN000919548	P		Seeded From UniProt	complete
involved_in	GO:0030182	neuron differentiation	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000919548 RGD:2858 RGD:2859 RGD:2860	P		Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96398 PANTHER:PTN000919548 RGD:2858	F		Seeded From UniProt	complete
involved_in	GO:0007623	circadian rhythm	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96396 MGI:MGI:96397 MGI:MGI:96398 MGI:MGI:99414 PANTHER:PTN000919548	P		Seeded From UniProt	complete
colocalizes_with	GO:0005737	cytoplasm	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96396 MGI:MGI:96397 MGI:MGI:96398 MGI:MGI:99414 PANTHER:PTN000919548 RGD:2859 UniProtKB:Q02363	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0000575 MGI:MGI:96396 MGI:MGI:96397 MGI:MGI:96398 MGI:MGI:99414 PANTHER:PTN000919548 RGD:2858 RGD:2859 RGD:2860 UniProtKB:O73933 UniProtKB:P47928 UniProtKB:Q02363	C		Seeded From UniProt	complete
enables	GO:0003700	DNA-binding transcription factor activity	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:96396 MGI:MGI:96398 PANTHER:PTN000919548	F		Seeded From UniProt	complete
enables	GO:0001085	RNA polymerase II transcription factor binding	PMID:21873635^[4]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:99414 PANTHER:PTN000919548	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:1901342	regulation of vasculature development	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2858	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0090074	negative regulation of protein homodimerization activity	PMID:20231428^[5]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0070628	proteasome binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2858	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060426	lung vasculature development	PMID:17717145^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2679939	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060425	lung morphogenesis	PMID:17717145^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2679939	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0050774	negative regulation of dendrite morphogenesis	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2858	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0050679	positive regulation of epithelial cell proliferation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2858	P		Seeded From UniProt	complete
enables	GO:0047485	protein N-terminus binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2858	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0046677	response to antibiotic	PMID:17717145^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2679939	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045892	negative regulation of transcription, DNA-templated	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P41134	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045765	regulation of angiogenesis	PMID:12498716^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	regulates_o_has_participant:(CL:0000057)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045668	negative regulation of osteoblast differentiation	PMID:15161906^[8]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:1321394	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045602	negative regulation of endothelial cell differentiation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2858	P		Seeded From UniProt	complete
enables	GO:0043621	protein self-association	PMID:20231428^[5]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043433	negative regulation of DNA-binding transcription factor activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P41134	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043408	regulation of MAPK cascade	PMID:17717145^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2679939	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043392	negative regulation of DNA binding	PMID:1922066^[9]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043392	negative regulation of DNA binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2858	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043066	negative regulation of apoptotic process	PMID:17717145^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2679939	P	regulates_o_occurs_in:(EMAPA:16728) regulates_o_occurs_in:(CL:1001567)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043066	negative regulation of apoptotic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2858	P		Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2858	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0032963	collagen metabolic process	PMID:17717145^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2679939	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0032233	positive regulation of actin filament bundle assembly	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2858	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0032091	negative regulation of protein binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2858	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0031648	protein destabilization	PMID:15322112^[10]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:88177	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0031648	protein destabilization	PMID:15322112^[10]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030509	BMP signaling pathway	PMID:15820682^[11]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010629	negative regulation of gene expression	PMID:20231428^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010628	positive regulation of gene expression	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2858	P		Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2858	F		Seeded From UniProt	complete
enables	GO:0008022	protein C-terminus binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2858	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007507	heart development	PMID:15472070^[12]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:2384134 MGI:MGI:2679967	P	results_in_development_of:(EMAPA:16105)	Seeded From UniProt	complete
part_of	GO:0005813	centrosome	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2858	C		Seeded From UniProt	complete
part_of	GO:0005794	Golgi apparatus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P41134	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:9418957^[13]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:18577) part_of:(CL:0000218)\|part_of:(EMAPA:18577) part_of:(CL:0002377)	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:15322112^[10]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P41134	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:20231428^[5]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:19796622^[14]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:17717145^[6]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:16728) part_of:(CL:0000115)	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:15322112^[10]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2858	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001886	endothelial cell morphogenesis	PMID:17717145^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2679939	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0000122	negative regulation of transcription by RNA polymerase II	PMID:19217292^[2]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:1096381 MGI:MGI:99698	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0000122	negative regulation of transcription by RNA polymerase II	PMID:12498716^[7]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2858	P		Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41134 ensembl:ENSP00000365280	P		Seeded From UniProt	complete
involved_in	GO:0043433	negative regulation of DNA-binding transcription factor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41134 ensembl:ENSP00000365280	P		Seeded From UniProt	complete
part_of	GO:0005794	Golgi apparatus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41134 ensembl:ENSP00000365280	C		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41134 ensembl:ENSP00000365280	C		Seeded From UniProt	complete
involved_in	GO:1990090	cellular response to nerve growth factor stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41135 ensembl:ENSRNOP00000052261	P		Seeded From UniProt	complete
involved_in	GO:1903351	cellular response to dopamine	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41135 ensembl:ENSRNOP00000052261	P		Seeded From UniProt	complete
involved_in	GO:1901653	cellular response to peptide	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41135 ensembl:ENSRNOP00000052261	P		Seeded From UniProt	complete
involved_in	GO:1901342	regulation of vasculature development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41135 ensembl:ENSRNOP00000052261	P		Seeded From UniProt	complete
involved_in	GO:0071560	cellular response to transforming growth factor beta stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41135 ensembl:ENSRNOP00000052261	P		Seeded From UniProt	complete
involved_in	GO:0071364	cellular response to epidermal growth factor stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41135 ensembl:ENSRNOP00000052261	P		Seeded From UniProt	complete
enables	GO:0070628	proteasome binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41135 ensembl:ENSRNOP00000052261	F		Seeded From UniProt	complete
involved_in	GO:0050774	negative regulation of dendrite morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41135 ensembl:ENSRNOP00000052261	P		Seeded From UniProt	complete
involved_in	GO:0050679	positive regulation of epithelial cell proliferation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41135 ensembl:ENSRNOP00000052261	P		Seeded From UniProt	complete
enables	GO:0047485	protein N-terminus binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41135 ensembl:ENSRNOP00000052261	F		Seeded From UniProt	complete
involved_in	GO:0045602	negative regulation of endothelial cell differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41135 ensembl:ENSRNOP00000052261	P		Seeded From UniProt	complete
involved_in	GO:0043392	negative regulation of DNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41135 ensembl:ENSRNOP00000052261	P		Seeded From UniProt	complete
involved_in	GO:0043066	negative regulation of apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41135 ensembl:ENSRNOP00000052261	P		Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41135 ensembl:ENSRNOP00000052261	F		Seeded From UniProt	complete
involved_in	GO:0036164	cell-abiotic substrate adhesion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41135 ensembl:ENSRNOP00000052261	P		Seeded From UniProt	complete
involved_in	GO:0032233	positive regulation of actin filament bundle assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41135 ensembl:ENSRNOP00000052261	P		Seeded From UniProt	complete
involved_in	GO:0032091	negative regulation of protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41135 ensembl:ENSRNOP00000052261	P		Seeded From UniProt	complete
involved_in	GO:0030182	neuron differentiation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41135 ensembl:ENSRNOP00000052261	P		Seeded From UniProt	complete
involved_in	GO:0014070	response to organic cyclic compound	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41135 ensembl:ENSRNOP00000052261	P		Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41135 ensembl:ENSRNOP00000052261	P		Seeded From UniProt	complete
enables	GO:0008134	transcription factor binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41135 ensembl:ENSRNOP00000052261	F		Seeded From UniProt	complete
enables	GO:0008022	protein C-terminus binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41135 ensembl:ENSRNOP00000052261	F		Seeded From UniProt	complete
involved_in	GO:0007420	brain development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41135 ensembl:ENSRNOP00000052261	P		Seeded From UniProt	complete
part_of	GO:0005813	centrosome	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41135 ensembl:ENSRNOP00000052261	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41135 ensembl:ENSRNOP00000052261	C		Seeded From UniProt	complete
involved_in	GO:0000122	negative regulation of transcription by RNA polymerase II	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P41135 ensembl:ENSRNOP00000052261	P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR026052	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR026052	C		Seeded From UniProt	complete
involved_in	GO:0045892	negative regulation of transcription, DNA-templated	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR026052	P		Seeded From UniProt	complete
enables	GO:0046983	protein dimerization activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR011598 InterPro:IPR036638	F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0217	P		Seeded From UniProt	complete
involved_in	GO:0048511	rhythmic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0090	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Patil, M et al. (2017) Id1 Promotes Obesity by Suppressing Brown Adipose Thermogenesis and White Adipose Browning. Diabetes 66 1611-1625 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 Duffield, GE et al. (2009) A role for Id2 in regulating photic entrainment of the mammalian circadian system. Curr. Biol. 19 297-304 PubMed GONUTS page
↑ ^3.0 ^3.1 Bai, G et al. (2007) Id sustains Hes1 expression to inhibit precocious neurogenesis by releasing negative autoregulation of Hes1. Dev. Cell 13 283-97 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 ^4.6 ^4.7 ^4.8 ^4.9 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 Tanaka, A et al. (2010) Inhibition of endothelial cell activation by bHLH protein E2-2 and its impairment of angiogenesis. Blood 115 4138-47 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 ^6.3 ^6.4 ^6.5 ^6.6 ^6.7 Zhang, H et al. (2007) Inhibitor of differentiation 1 promotes endothelial survival in a bleomycin model of lung injury in mice. Am. J. Pathol. 171 1113-26 PubMed GONUTS page
↑ ^7.0 ^7.1 Volpert, OV et al. (2002) Id1 regulates angiogenesis through transcriptional repression of thrombospondin-1. Cancer Cell 2 473-83 PubMed GONUTS page
↑ Peng, Y et al. (2004) Inhibitor of DNA binding/differentiation helix-loop-helix proteins mediate bone morphogenetic protein-induced osteoblast differentiation of mesenchymal stem cells. J. Biol. Chem. 279 32941-9 PubMed GONUTS page
↑ Sun, XH et al. (1991) Id proteins Id1 and Id2 selectively inhibit DNA binding by one class of helix-loop-helix proteins. Mol. Cell. Biol. 11 5603-11 PubMed GONUTS page
↑ ^10.0 ^10.1 ^10.2 ^10.3 Viñals, F & Ventura, F (2004) Myogenin protein stability is decreased by BMP-2 through a mechanism implicating Id1. J. Biol. Chem. 279 45766-72 PubMed GONUTS page
↑ Yamashita, M et al. (2005) Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation. Cell 121 101-13 PubMed GONUTS page
↑ Fraidenraich, D et al. (2004) Rescue of cardiac defects in id knockout embryos by injection of embryonic stem cells. Science 306 247-52 PubMed GONUTS page
↑ Stewart, HJ et al. (1997) Helix-loop-helix proteins in Schwann cells: a study of regulation and subcellular localization of Ids, REB, and E12/47 during embryonic and postnatal development. J. Neurosci. Res. 50 684-701 PubMed GONUTS page
↑ Nishiyama, A et al. (2009) Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors. Cell Stem Cell 5 420-33 PubMed GONUTS page

[PMID:28270523-1] Patil, M et al. (2017) Id1 Promotes Obesity by Suppressing Brown Adipose Thermogenesis and White Adipose Browning. Diabetes 66 1611-1625 PubMed GONUTS page

[PMID:19217292-2] 2.0 ^2.1 ^2.2 Duffield, GE et al. (2009) A role for Id2 in regulating photic entrainment of the mammalian circadian system. Curr. Biol. 19 297-304 PubMed GONUTS page

[PMID:17681138-3] 3.0 ^3.1 Bai, G et al. (2007) Id sustains Hes1 expression to inhibit precocious neurogenesis by releasing negative autoregulation of Hes1. Dev. Cell 13 283-97 PubMed GONUTS page

[PMID:21873635-4] 4.0 ^4.1 ^4.2 ^4.3 ^4.4 ^4.5 ^4.6 ^4.7 ^4.8 ^4.9 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:20231428-5] 5.0 ^5.1 ^5.2 ^5.3 Tanaka, A et al. (2010) Inhibition of endothelial cell activation by bHLH protein E2-2 and its impairment of angiogenesis. Blood 115 4138-47 PubMed GONUTS page

[PMID:17717145-6] 6.0 ^6.1 ^6.2 ^6.3 ^6.4 ^6.5 ^6.6 ^6.7 Zhang, H et al. (2007) Inhibitor of differentiation 1 promotes endothelial survival in a bleomycin model of lung injury in mice. Am. J. Pathol. 171 1113-26 PubMed GONUTS page

[PMID:12498716-7] 7.0 ^7.1 Volpert, OV et al. (2002) Id1 regulates angiogenesis through transcriptional repression of thrombospondin-1. Cancer Cell 2 473-83 PubMed GONUTS page

[PMID:15161906-8] Peng, Y et al. (2004) Inhibitor of DNA binding/differentiation helix-loop-helix proteins mediate bone morphogenetic protein-induced osteoblast differentiation of mesenchymal stem cells. J. Biol. Chem. 279 32941-9 PubMed GONUTS page

[PMID:1922066-9] Sun, XH et al. (1991) Id proteins Id1 and Id2 selectively inhibit DNA binding by one class of helix-loop-helix proteins. Mol. Cell. Biol. 11 5603-11 PubMed GONUTS page

[PMID:15322112-10] 10.0 ^10.1 ^10.2 ^10.3 Viñals, F & Ventura, F (2004) Myogenin protein stability is decreased by BMP-2 through a mechanism implicating Id1. J. Biol. Chem. 279 45766-72 PubMed GONUTS page

[PMID:15820682-11] Yamashita, M et al. (2005) Ubiquitin ligase Smurf1 controls osteoblast activity and bone homeostasis by targeting MEKK2 for degradation. Cell 121 101-13 PubMed GONUTS page

[PMID:15472070-12] Fraidenraich, D et al. (2004) Rescue of cardiac defects in id knockout embryos by injection of embryonic stem cells. Science 306 247-52 PubMed GONUTS page

[PMID:9418957-13] Stewart, HJ et al. (1997) Helix-loop-helix proteins in Schwann cells: a study of regulation and subcellular localization of Ids, REB, and E12/47 during embryonic and postnatal development. J. Neurosci. Res. 50 684-701 PubMed GONUTS page

[PMID:19796622-14] Nishiyama, A et al. (2009) Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors. Cell Stem Cell 5 420-33 PubMed GONUTS page

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MOUSE:ID1

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