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MOUSE:HYAS1
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Has1 (synonyms: Has) | |
| Protein Name(s) | Hyaluronan synthase 1
Hyaluronate synthase 1 Hyaluronic acid synthase 1 HA synthase 1 | |
| External Links | ||
| UniProt | Q61647 | |
| EMBL | D82964 | |
| CCDS | CCDS37459.1 | |
| RefSeq | NP_032241.1 | |
| UniGene | Mm.255701 | |
| ProteinModelPortal | Q61647 | |
| CAZy | GT2 | |
| PhosphoSite | Q61647 | |
| PRIDE | Q61647 | |
| Ensembl | ENSMUST00000003762 | |
| GeneID | 15116 | |
| KEGG | mmu:15116 | |
| UCSC | uc008apr.2 | |
| CTD | 3036 | |
| MGI | MGI:106590 | |
| eggNOG | COG1215 | |
| GeneTree | ENSGT00390000010337 | |
| HOGENOM | HOG000112847 | |
| HOVERGEN | HBG000189 | |
| InParanoid | Q61647 | |
| KO | K00752 | |
| OMA | RTHRCVC | |
| OrthoDB | EOG77WWBZ | |
| PhylomeDB | Q61647 | |
| TreeFam | TF332506 | |
| BRENDA | 2.4.1.212 | |
| Reactome | REACT_196552 | |
| UniPathway | UPA00341 | |
| NextBio | 287530 | |
| PRO | PR:Q61647 | |
| Proteomes | UP000000589 | |
| Bgee | Q61647 | |
| CleanEx | MM_HAS1 | |
| ExpressionAtlas | Q61647 | |
| Genevestigator | Q61647 | |
| GO | GO:0016021 GO:0016020 GO:0050501 GO:0036120 GO:0085029 GO:0045226 GO:0030213 GO:0010764 | |
| Gene3D | 3.90.550.10 | |
| InterPro | IPR026107 IPR028385 IPR029044 | |
| PANTHER | PTHR22913 PTHR22913:SF4 | |
| SUPFAM | SSF53448 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0005737 |
cytoplasm |
ECO:0000314 |
C |
Figures 1, 2, 3, 4 |
complete | |||||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0085029 |
extracellular matrix assembly |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050501 |
hyaluronan synthase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0045226 |
extracellular polysaccharide biosynthetic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0085029 |
extracellular matrix assembly |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:106590 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0050501 |
hyaluronan synthase activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:106590 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0045226 |
extracellular polysaccharide biosynthetic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:106590 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030213 |
hyaluronan biosynthetic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:106590 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005887 |
integral component of plasma membrane |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000530809 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0050501 |
hyaluronan synthase activity |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0036120 |
cellular response to platelet-derived growth factor stimulus |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0030213 |
hyaluronan biosynthetic process |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0010764 |
negative regulation of fibroblast migration |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0044849 |
estrous cycle |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q8CH93 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0042802 |
identical protein binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q92839 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0036120 |
cellular response to platelet-derived growth factor stimulus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q92839 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0010764 |
negative regulation of fibroblast migration |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q92839 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030213 |
hyaluronan biosynthetic process |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050501 |
hyaluronan synthase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0050501 |
hyaluronan synthase activity |
ECO:0000501 |
evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016740 |
transferase activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016021 |
integral component of membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0016020 |
membrane |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016757 |
transferase activity, transferring glycosyl groups |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0030213 |
hyaluronan biosynthetic process |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00341 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Törrönen, K et al. (2014) Tissue distribution and subcellular localization of hyaluronan synthase isoenzymes. Histochem. Cell Biol. 141 17-31 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Itano, N et al. (1999) Three isoforms of mammalian hyaluronan synthases have distinct enzymatic properties. J. Biol. Chem. 274 25085-92 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Yoshida, M et al. (2000) In vitro synthesis of hyaluronan by a single protein derived from mouse HAS1 gene and characterization of amino acid residues essential for the activity. J. Biol. Chem. 275 497-506 PubMed GONUTS page
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