MOUSE:HXK1

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Hk1
Protein Name(s)	Hexokinase-1 Hexokinase type I HK I Hexokinase, tumor isozyme
External Links
UniProt	P17710
EMBL	J05277 L16948 L16949 L16950 AC126428 AC145297
CCDS	CCDS48577.1 CCDS48578.1
PIR	A35244 I49744
RefSeq	XP_006513305.1 XP_006513306.1 XP_006513307.1 XP_006513308.1
UniGene	Mm.196605
ProteinModelPortal	P17710
SMR	P17710
IntAct	P17710
MINT	MINT-1847872
PhosphoSite	P17710
MaxQB	P17710
PaxDb	P17710
PRIDE	P17710
Ensembl	ENSMUST00000072357 ENSMUST00000099691 ENSMUST00000116238
GeneID	15275
KEGG	mmu:15275
UCSC	uc007fgz.2
CTD	3098
MGI	MGI:96103
eggNOG	COG5026
GeneTree	ENSGT00390000017159
HOGENOM	HOG000162671
HOVERGEN	HBG005020
InParanoid	P17710
KO	K00844
OMA	KFKASGV
OrthoDB	EOG7S21X5
TreeFam	TF314238
Reactome	REACT_253543
SABIO-RK	P17710
UniPathway	UPA00242
PRO	PR:P17710
Proteomes	UP000000589
Bgee	P17710
CleanEx	MM_HK1
ExpressionAtlas	P17710
Genevestigator	P17710
GO	GO:0005929 GO:0005829 GO:0045121 GO:0005741 GO:0005739 GO:0097228 GO:0005524 GO:0008865 GO:0004340 GO:0004396 GO:0019158 GO:0061621 GO:0046835 GO:0001678 GO:0051156 GO:0006096
InterPro	IPR001312 IPR022673 IPR019807 IPR022672
PANTHER	PTHR19443
Pfam	PF00349 PF03727
PRINTS	PR00475
PROSITE	PS00378

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
enables	GO:0042834	peptidoglycan binding	PMID:27374331^[1]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	PMID:27374331^[1]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(GO:0071224)	Seeded From UniProt	complete
involved_in	GO:0002741	positive regulation of cytokine secretion involved in immune response	PMID:27374331^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0050718	positive regulation of interleukin-1 beta secretion	PMID:27374331^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	PMID:27374331^[1]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0046835	carbohydrate phosphorylation	PMID:27374331^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0004396	hexokinase activity	PMID:27374331^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0019158	mannokinase activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000455350 PomBase:SPAC24H6.04 PomBase:SPAC4F8.07c	F		Seeded From UniProt	complete
enables	GO:0008865	fructokinase activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000455350 PomBase:SPAC24H6.04 PomBase:SPAC4F8.07c TAIR:locus:2008031 TAIR:locus:2087590 TAIR:locus:2119931 TAIR:locus:2137564 TAIR:locus:2202410 UniProtKB:P93834 UniProtKB:Q4WHC3	F		Seeded From UniProt	complete
involved_in	GO:0006096	glycolytic process	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000455350 RGD:2670 RGD:2796 SGD:S000000545 SGD:S000001949 SGD:S000003222	P		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1270854 MGI:MGI:96103 PANTHER:PTN000455350 RGD:2670 RGD:2796 SGD:S000003222 UniProtKB:C6KT76 UniProtKB:P35557	C		Seeded From UniProt	complete
enables	GO:0004340	glucokinase activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1270854 MGI:MGI:96103 PANTHER:PTN000455350 PomBase:SPAC24H6.04 PomBase:SPAC4F8.07c RGD:2670 RGD:2796 SGD:S000000545 TAIR:locus:2008031 TAIR:locus:2087590 TAIR:locus:2119931 TAIR:locus:2137564 TAIR:locus:2202410 UniProtKB:P35557 UniProtKB:P93834 UniProtKB:Q4WCS2 UniProtKB:Q4WHC3 UniProtKB:Q5W676 UniProtKB:Q8LQ68	F		Seeded From UniProt	complete
involved_in	GO:0001678	cellular glucose homeostasis	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1270854 PANTHER:PTN000455350 RGD:2670	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0072656	maintenance of protein location in mitochondrion	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P19367	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0072655	establishment of protein localization to mitochondrion	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P19367	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0046835	carbohydrate phosphorylation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P19367	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0046835	carbohydrate phosphorylation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2796	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0046777	protein autophosphorylation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2796	P		Seeded From UniProt	complete
part_of	GO:0045121	membrane raft	PMID:19144954^[3]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000019)	Seeded From UniProt	complete
enables	GO:0044877	protein-containing complex binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2796	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0043066	negative regulation of apoptotic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2796	P		Seeded From UniProt	complete
enables	GO:0042834	peptidoglycan binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P19367	F		Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2796	F		Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P19367	F		Seeded From UniProt	complete
part_of	GO:0032991	protein-containing complex	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2796	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0018108	peptidyl-tyrosine phosphorylation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2796	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0018107	peptidyl-threonine phosphorylation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2796	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0018105	peptidyl-serine phosphorylation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2796	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010359	regulation of anion channel activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2796	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006468	protein phosphorylation	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2796	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006096	glycolytic process	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2796	P		Seeded From UniProt	complete
part_of	GO:0005901	caveola	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2796	C		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	PMID:12420306^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2796	C		Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	PMID:18614015^[5]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	PMID:14651853^[6]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(EMAPA:16846)\|part_of:(EMAPA:16894)\|part_of:(EMAPA:17373)\|part_of:(EMAPA:16105)	Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	PMID:17069463^[7]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0002609)	Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P19367	C		Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2796	C		Seeded From UniProt	complete
enables	GO:0005536	glucose binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2796	F		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2796	F		Seeded From UniProt	complete
enables	GO:0004672	protein kinase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2796	F		Seeded From UniProt	complete
enables	GO:0004396	hexokinase activity	PMID:18165236^[8]	ECO:0000314	direct assay evidence used in manual assertion		F	occurs_in:(EMAPA:16846)	Seeded From UniProt	complete
enables	GO:0004396	hexokinase activity	PMID:15155459^[9]	ECO:0000314	direct assay evidence used in manual assertion		F	occurs_in:(EMAPA:16332)	Seeded From UniProt	complete
enables	GO:0004396	hexokinase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P19367	F		Seeded From UniProt	complete
enables	GO:0004396	hexokinase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2796	F		Seeded From UniProt	complete
enables	GO:0004340	glucokinase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2796	F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0002931	response to ischemia	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:2796	P		Seeded From UniProt	complete
involved_in	GO:0051156	glucose 6-phosphate metabolic process	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0004340	P		Seeded From UniProt	complete
involved_in	GO:0051156	glucose 6-phosphate metabolic process	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0004340	P		Seeded From UniProt	complete
involved_in	GO:0072656	maintenance of protein location in mitochondrion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P19367 ensembl:ENSP00000494664	P		Seeded From UniProt	complete
involved_in	GO:0072655	establishment of protein localization to mitochondrion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P19367 ensembl:ENSP00000494664	P		Seeded From UniProt	complete
involved_in	GO:0046835	carbohydrate phosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P19367 ensembl:ENSP00000494664	P		Seeded From UniProt	complete
enables	GO:0042834	peptidoglycan binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P19367 ensembl:ENSP00000494664	F		Seeded From UniProt	complete
enables	GO:0042802	identical protein binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P19367 ensembl:ENSP00000494664	F		Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P19367 ensembl:ENSP00000494664	C		Seeded From UniProt	complete
enables	GO:0004396	hexokinase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P19367 ensembl:ENSP00000494664	F		Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:A0A024QZK7 ensembl:ENSP00000494664	C		Seeded From UniProt	complete
involved_in	GO:0001678	cellular glucose homeostasis	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001312	P		Seeded From UniProt	complete
enables	GO:0004396	hexokinase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001312 InterPro:IPR019807	F		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001312 InterPro:IPR019807 InterPro:IPR022672 InterPro:IPR022673	F		Seeded From UniProt	complete
enables	GO:0005536	glucose binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001312	F		Seeded From UniProt	complete
involved_in	GO:0005975	carbohydrate metabolic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001312 InterPro:IPR022672 InterPro:IPR022673	P		Seeded From UniProt	complete
involved_in	GO:0006096	glycolytic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR019807	P		Seeded From UniProt	complete
enables	GO:0016773	phosphotransferase activity, alcohol group as acceptor	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR022672 InterPro:IPR022673	F		Seeded From UniProt	complete
enables	GO:0004396	hexokinase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:2.7.1.1	F		Seeded From UniProt	complete
part_of	GO:0097228	sperm principal piece	PMID:19889946^[10]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000019)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0061621	canonical glycolysis	PMID:18618018^[11]	ECO:0000305	curator inference used in manual assertion	GO:0004340	P	occurs_in:(CL:0000019)	Seeded From UniProt	complete
part_of	GO:0005929	cilium	PMID:16687649^[12]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000019)	Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	PMID:12420306^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0004340	glucokinase activity	PMID:18509164^[13]	ECO:0000314	direct assay evidence used in manual assertion		F	occurs_in:(CL:0000019)	Seeded From UniProt	complete
involved_in	GO:0051156	glucose 6-phosphate metabolic process	GO_REF:0000108	ECO:0000364	evidence based on logical inference from manual annotation used in automatic assertion	GO:0004340	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0006096	glycolytic process	PMID:12420306^[4]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
enables	GO:0004396	hexokinase activity	PMID:12420306^[4]	ECO:0000304	author statement supported by traceable reference used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003824	catalytic activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0021	F		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472 UniProtKB-SubCell:SL-0162	C		Seeded From UniProt	complete
involved_in	GO:0016310	phosphorylation	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	P		Seeded From UniProt	complete
part_of	GO:0005739	mitochondrion	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0496	C		Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F		Seeded From UniProt	complete
enables	GO:0016301	kinase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0418	F		Seeded From UniProt	complete
part_of	GO:0005741	mitochondrial outer membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1000 UniProtKB-SubCell:SL-0172	C		Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F		Seeded From UniProt	complete
involved_in	GO:0006096	glycolytic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0324	P		Seeded From UniProt	complete
involved_in	GO:0008152	metabolic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0021	P		Seeded From UniProt	complete
involved_in	GO:0019318	hexose metabolic process	GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniPathway:UPA00242	P		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 Wolf, AJ et al. (2016) Hexokinase Is an Innate Immune Receptor for the Detection of Bacterial Peptidoglycan. Cell 166 624-636 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Miranda, PV et al. (2009) Localization of low-density detergent-resistant membrane proteins in intact and acrosome-reacted mouse sperm. Biol. Reprod. 80 897-904 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 Nakamura, N et al. (2003) Sorting specificity of spermatogenic cell specific region of mouse hexokinase-s (mHk1-s). Mol. Reprod. Dev. 64 113-9 PubMed GONUTS page
↑ Pagliarini, DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134 112-23 PubMed GONUTS page
↑ Mootha, VK et al. (2003) Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell 115 629-40 PubMed GONUTS page
↑ Aslanukov, A et al. (2006) RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism. PLoS Genet. 2 e177 PubMed GONUTS page
↑ Cifuentes, D et al. (2008) Hepatic glycogen synthesis in the absence of glucokinase: the case of embryonic liver. J. Biol. Chem. 283 5642-9 PubMed GONUTS page
↑ White, RA et al. (2004) Chromosomal localization, hematologic characterization, and iron metabolism of the hereditary erythroblastic anemia (hea) mutant mouse. Blood 104 1511-8 PubMed GONUTS page
↑ Nakamura, N et al. (2010) Molecular complex of three testis-specific isozymes associated with the mouse sperm fibrous sheath: hexokinase 1, phosphofructokinase M, and glutathione S-transferase mu class 5. Biol. Reprod. 82 504-15 PubMed GONUTS page
↑ Bersenev, A et al. (2008) Lnk controls mouse hematopoietic stem cell self-renewal and quiescence through direct interactions with JAK2. J. Clin. Invest. 118 2832-44 PubMed GONUTS page
↑ Krisfalusi, M et al. (2006) Multiple glycolytic enzymes are tightly bound to the fibrous sheath of mouse spermatozoa. Biol. Reprod. 75 270-8 PubMed GONUTS page
↑ Nakamura, N et al. (2008) Cleavage of disulfide bonds in mouse spermatogenic cell-specific type 1 hexokinase isozyme is associated with increased hexokinase activity and initiation of sperm motility. Biol. Reprod. 79 537-45 PubMed GONUTS page

[PMID:27374331-1] 1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 Wolf, AJ et al. (2016) Hexokinase Is an Innate Immune Receptor for the Detection of Bacterial Peptidoglycan. Cell 166 624-636 PubMed GONUTS page

[PMID:21873635-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:19144954-3] Miranda, PV et al. (2009) Localization of low-density detergent-resistant membrane proteins in intact and acrosome-reacted mouse sperm. Biol. Reprod. 80 897-904 PubMed GONUTS page

[PMID:12420306-4] 4.0 ^4.1 ^4.2 ^4.3 Nakamura, N et al. (2003) Sorting specificity of spermatogenic cell specific region of mouse hexokinase-s (mHk1-s). Mol. Reprod. Dev. 64 113-9 PubMed GONUTS page

[PMID:18614015-5] Pagliarini, DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134 112-23 PubMed GONUTS page

[PMID:14651853-6] Mootha, VK et al. (2003) Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell 115 629-40 PubMed GONUTS page

[PMID:17069463-7] Aslanukov, A et al. (2006) RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism. PLoS Genet. 2 e177 PubMed GONUTS page

[PMID:18165236-8] Cifuentes, D et al. (2008) Hepatic glycogen synthesis in the absence of glucokinase: the case of embryonic liver. J. Biol. Chem. 283 5642-9 PubMed GONUTS page

[PMID:15155459-9] White, RA et al. (2004) Chromosomal localization, hematologic characterization, and iron metabolism of the hereditary erythroblastic anemia (hea) mutant mouse. Blood 104 1511-8 PubMed GONUTS page

[PMID:19889946-10] Nakamura, N et al. (2010) Molecular complex of three testis-specific isozymes associated with the mouse sperm fibrous sheath: hexokinase 1, phosphofructokinase M, and glutathione S-transferase mu class 5. Biol. Reprod. 82 504-15 PubMed GONUTS page

[PMID:18618018-11] Bersenev, A et al. (2008) Lnk controls mouse hematopoietic stem cell self-renewal and quiescence through direct interactions with JAK2. J. Clin. Invest. 118 2832-44 PubMed GONUTS page

[PMID:16687649-12] Krisfalusi, M et al. (2006) Multiple glycolytic enzymes are tightly bound to the fibrous sheath of mouse spermatozoa. Biol. Reprod. 75 270-8 PubMed GONUTS page

[PMID:18509164-13] Nakamura, N et al. (2008) Cleavage of disulfide bonds in mouse spermatogenic cell-specific type 1 hexokinase isozyme is associated with increased hexokinase activity and initiation of sperm motility. Biol. Reprod. 79 537-45 PubMed GONUTS page

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MOUSE:HXK1

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