MOUSE:GUC2F

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Gucy2f
Protein Name(s)	Retinal guanylyl cyclase 2
External Links
UniProt	Q5SDA5
EMBL	AY651761 AL671916 BX324191 BX324191 AL671916 BC115714 AK044234
CCDS	CCDS30446.1
RefSeq	NP_001007577.1 XP_006528904.1
UniGene	Mm.208511
ProteinModelPortal	Q5SDA5
SMR	Q5SDA5
STRING	10090.ENSMUSP00000044521
PhosphoSite	Q5SDA5
PRIDE	Q5SDA5
Ensembl	ENSMUST00000042530
GeneID	245650
KEGG	mmu:245650
UCSC	uc009ulq.2
CTD	2986
MGI	MGI:105119
eggNOG	COG0515
GeneTree	ENSGT00760000118959
HOGENOM	HOG000293307
HOVERGEN	HBG098487
InParanoid	Q5SDA5
KO	K12321
OMA	NSIYFIA
OrthoDB	EOG7QVM1V
PhylomeDB	Q5SDA5
TreeFam	TF106338
Reactome	REACT_188266
NextBio	386884
PRO	PR:Q5SDA5
Proteomes	UP000000589
Bgee	Q5SDA5
CleanEx	MM_GUCY2F
Genevestigator	Q5SDA5
GO	GO:0016021 GO:0005524 GO:0005525 GO:0004383 GO:0004672 GO:0035556 GO:0007601
Gene3D	3.30.70.1230
InterPro	IPR001054 IPR018297 IPR001828 IPR011009 IPR029787 IPR028082 IPR000719 IPR001245
Pfam	PF01094 PF00211 PF07714
SMART	SM00044
SUPFAM	SSF53822 SSF55073 SSF56112
PROSITE	PS00452 PS50125 PS50011

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
	GO:0050908	detection of light stimulus involved in visual perception	PMID:17255100^[1]	ECO:0000315			P	Figure 2B: At high intensity light stimulus, the a-wave and sensitivity of the scotopic GC2 (GUCY2F) -/- mouse were slightly reduced compared to the WT.	complete CACAO 4455
involved_in	GO:0050908	detection of light stimulus involved in visual perception	PMID:17255100^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0007168	receptor guanylyl cyclase signaling pathway	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000229249 UniProtKB:P16066 UniProtKB:P20594	P	Seeded From UniProt	complete
involved_in	GO:0007165	signal transduction	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000228924 dictyBase:DDB_G0274569	P	Seeded From UniProt	complete
involved_in	GO:0006182	cGMP biosynthetic process	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000229249 UniProtKB:P16066 UniProtKB:P20594	P	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000228924 RGD:3195 RGD:620438 RGD:620439 RGD:620851 UniProtKB:P20594 UniProtKB:P9WQ35	C	Seeded From UniProt	complete
enables	GO:0004383	guanylate cyclase activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0266136 MGI:MGI:106025 MGI:MGI:106903 MGI:MGI:97371 MGI:MGI:97372 PANTHER:PTN000229249 RGD:2771 RGD:3195 RGD:620438 RGD:620439 UniProtKB:P16066 UniProtKB:P20594 WB:WBGene00001535 WB:WBGene00001538 WB:WBGene00020131 ZFIN:ZDB-GENE-011128-7	F	Seeded From UniProt	complete
enables	GO:0001653	peptide receptor activity	PMID:21873635^[2]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0266136 PANTHER:PTN000229249	F	Seeded From UniProt	complete
enables	GO:0046982	protein heterodimerization activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:620439	F	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:620439	F	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0019934	cGMP-mediated signaling	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:620439	P	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:620439	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:620439	C	Seeded From UniProt	complete
enables	GO:0004383	guanylate cyclase activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:620439	F	Seeded From UniProt	complete
enables	GO:0046982	protein heterodimerization activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51842 ensembl:ENSRNOP00000049500	F	Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51842 ensembl:ENSRNOP00000049500	F	Seeded From UniProt	complete
involved_in	GO:0019934	cGMP-mediated signaling	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51842 ensembl:ENSRNOP00000049500	P	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51842 ensembl:ENSRNOP00000049500	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51842 ensembl:ENSRNOP00000049500	C	Seeded From UniProt	complete
enables	GO:0004383	guanylate cyclase activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P51842 ensembl:ENSRNOP00000049500	F	Seeded From UniProt	complete
enables	GO:0004672	protein kinase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR001245	F	Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719	F	Seeded From UniProt	complete
involved_in	GO:0006468	protein phosphorylation	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000719 InterPro:IPR001245	P	Seeded From UniProt	complete
involved_in	GO:0009190	cyclic nucleotide biosynthetic process	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001054 InterPro:IPR018297	P	Seeded From UniProt	complete
enables	GO:0016849	phosphorus-oxygen lyase activity	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001054 InterPro:IPR018297	F	Seeded From UniProt	complete
involved_in	GO:0035556	intracellular signal transduction	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001054 InterPro:IPR018297	P	Seeded From UniProt	complete
enables	GO:0004383	guanylate cyclase activity	GO_REF:0000003	ECO:0000501	evidence used in automatic assertion	EC:4.6.1.2	F	Seeded From UniProt	complete
enables	GO:0016829	lyase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0456	F	Seeded From UniProt	complete
enables	GO:0005525	GTP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0342	F	Seeded From UniProt	complete
involved_in	GO:0006182	cGMP biosynthetic process	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0141	P	Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C	Seeded From UniProt	complete
involved_in	GO:0050896	response to stimulus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0716	P	Seeded From UniProt	complete
involved_in	GO:0007601	visual perception	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0844	P	Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F	Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472 UniProtKB-SubCell:SL-0162	C	Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Baehr, W et al. (2007) The function of guanylate cyclase 1 and guanylate cyclase 2 in rod and cone photoreceptors. J. Biol. Chem. 282 8837-47 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:17255100-1] 1.0 ^1.1 Baehr, W et al. (2007) The function of guanylate cyclase 1 and guanylate cyclase 2 in rod and cone photoreceptors. J. Biol. Chem. 282 8837-47 PubMed GONUTS page

[PMID:21873635-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[1]

[2]

MOUSE:GUC2F

Contents

Annotations

Notes

References

a

c

d

e

g

i

l

m

n

p

r

s

v

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools