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MOUSE:FBX11
Contents
Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
Gene Name(s) | Fbxo11 | |
Protein Name(s) | F-box only protein 11 | |
External Links | ||
UniProt | Q7TPD1 | |
EMBL | AC087233 AC154673 BC049946 BC055343 BC117884 BC117885 BC128479 | |
CCDS | CCDS37717.1 | |
RefSeq | NP_001074503.1 XP_006524267.1 | |
UniGene | Mm.386857 | |
ProteinModelPortal | Q7TPD1 | |
DIP | DIP-59433N | |
PhosphoSite | Q7TPD1 | |
MaxQB | Q7TPD1 | |
PaxDb | Q7TPD1 | |
PRIDE | Q7TPD1 | |
Ensembl | ENSMUST00000005504 | |
GeneID | 225055 | |
KEGG | mmu:225055 | |
CTD | 80204 | |
MGI | MGI:2147134 | |
eggNOG | NOG12793 | |
GeneTree | ENSGT00530000063425 | |
HOGENOM | HOG000020584 | |
HOVERGEN | HBG051565 | |
InParanoid | Q7TPD1 | |
KO | K10297 | |
OMA | VPHHKHY | |
OrthoDB | EOG73803Z | |
TreeFam | TF313602 | |
UniPathway | UPA00143 | |
ChiTaRS | Fbxo11 | |
NextBio | 377524 | |
PRO | PR:Q7TPD1 | |
Proteomes | UP000000589 | |
Bgee | E9QP06 | |
CleanEx | MM_FBXO11 | |
ExpressionAtlas | Q7TPD1 | |
Genevestigator | Q7TPD1 | |
GO | GO:0005694 GO:0005737 GO:0005730 GO:0016274 GO:0004842 GO:0008270 GO:0007605 | |
Gene3D | 2.160.20.10 | |
InterPro | IPR006633 IPR001810 IPR029799 IPR022441 IPR006626 IPR012334 IPR011050 IPR003126 | |
PANTHER | PTHR22990:SF12 | |
Pfam | PF12937 PF02207 | |
SMART | SM00722 SM00256 SM00710 | |
SUPFAM | SSF51126 SSF81383 | |
TIGRFAMs | TIGR03804 | |
PROSITE | PS50181 PS51157 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
GO:0004842 |
ubiquitin-protein ligase activity |
ECO:0000315 |
F |
Figure 1 show that FBOX proteins were flagged and immunoblotting indicated that FBXO11 is directly involved in ubiquitin-mediated degradation of BCL6 |
complete | |||||
enables |
GO:0004842 |
ubiquitin-protein transferase activity |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007605 |
sensory perception of sound |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0016274 |
protein-arginine N-methyltransferase activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
acts_upstream_of_or_within |
GO:0007605 |
sensory perception of sound |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:1861993 |
P |
Seeded From UniProt |
complete | ||
acts_upstream_of_or_within |
GO:0006464 |
cellular protein modification process |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005829 |
cytosol |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005730 |
nucleolus |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0035246 |
peptidyl-arginine N-methylation |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0016274 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0035246 |
peptidyl-arginine N-methylation |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0016274 |
P |
Seeded From UniProt |
complete | ||
enables |
GO:0016274 |
protein-arginine N-methyltransferase activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q86XK2 |
F |
Seeded From UniProt |
complete | ||
involved_in |
GO:0006464 |
cellular protein modification process |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q86XK2 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005829 |
cytosol |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q86XK2 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005737 |
cytoplasm |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q86XK2 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005730 |
nucleolus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q86XK2 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0005634 |
nucleus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q86XK2 |
C |
Seeded From UniProt |
complete | ||
part_of |
GO:0000151 |
ubiquitin ligase complex |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
enables |
GO:0008270 |
zinc ion binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016567 |
protein ubiquitination |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005694 |
chromosome |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0016567 |
protein ubiquitination |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
UniPathway:UPA00143 |
P |
Seeded From UniProt |
complete | ||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Duan, S et al. (2012) FBXO11 targets BCL6 for degradation and is inactivated in diffuse large B-cell lymphomas. Nature 481 90-3 PubMed GONUTS page
- ↑ Hardisty-Hughes, RE et al. (2006) A mutation in the F-box gene, Fbxo11, causes otitis media in the Jeff mouse. Hum. Mol. Genet. 15 3273-9 PubMed GONUTS page
- ↑ Nolan, PM et al. (2000) A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse. Nat. Genet. 25 440-3 PubMed GONUTS page