MOUSE:ELAV1

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Elavl1 (synonyms: Elra, Hua)
Protein Name(s)	ELAV-like protein 1 Elav-like generic protein Hu-antigen R HuR MelG
External Links
UniProt	P70372
EMBL	U65735 AK080365 CH466566 CH466566 U17595
CCDS	CCDS22084.1
PIR	I49144
RefSeq	NP_034615.2 XP_006508761.1
UniGene	Mm.119162
ProteinModelPortal	P70372
SMR	P70372
BioGrid	200482
DIP	DIP-46480N
IntAct	P70372
MINT	MINT-4094207
STRING	10090.ENSMUSP00000096549
iPTMnet	P70372
PhosphoSite	P70372
EPD	P70372
MaxQB	P70372
PaxDb	P70372
PRIDE	P70372
TopDownProteomics	P70372
Ensembl	ENSMUST00000098950 ENSMUST00000209010
GeneID	15568
KEGG	mmu:15568
UCSC	uc009kts.1
CTD	1994
MGI	MGI:1100851
eggNOG	KOG0145 ENOG410XP7S
GeneTree	ENSGT00760000118913
HOGENOM	HOG000231162
HOVERGEN	HBG002295
InParanoid	P70372
KO	K13088
OMA	EDHMADE
OrthoDB	EOG77T14R
TreeFam	TF313377
Reactome	[www.reactome.org/content/detail/R-MMU-450520 R-MMU-450520] [www.reactome.org/content/detail/R-MMU-72163 R-MMU-72163]
ChiTaRS	Elavl1
PRO	PR:P70372
Proteomes	UP000000589
Bgee	P70372
Genevisible	P70372
GO	GO:0005737 GO:0005829 GO:0016020 GO:0005654 GO:0005634 GO:0017091 GO:0003725 GO:0035925 GO:0003730 GO:0000166 GO:0044822 GO:0042803 GO:0019901 GO:0003723 GO:0070935 GO:0048255 GO:0045727 GO:2000036
Gene3D	3.30.70.330
InterPro	IPR006548 IPR002343 IPR012677 IPR000504
Pfam	PF00076
PRINTS	PR00961
SMART	SM00360
SUPFAM	SSF54928
TIGRFAMs	TIGR01661
PROSITE	PS50102

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0005634	nucleus	PMID:27609837^[1]	ECO:0000314	direct assay evidence used in manual assertion		C		Mouse ELAVL1/Hua(Hur). HuR shuttles between the nucleus and the cytosol but is predominantly nuclear in non-dividing cells (Fig. 1A).	complete CACAO 12229
	GO:0005783	endoplasmic reticulum	PMID:27609837^[1]	ECO:0000314	direct assay evidence used in manual assertion		C		Mouse (ELAV1/Hua) Cytosolic HuR extensively co-localized with the endoplasmic reticulum (ER) marker calnexin, both in the absence and presence of CGP-74514A (Fig. 1A), demonstrating that extranuclear HuR is associated with the ER.	complete CACAO 12230
	GO:0048255	mRNA stabilization	PMID:27609837^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Mouse (ELAV1/Hua/HUR) The half-life of Kpnb1 mRNA was found to be 16.5±0.75 h and 10.2±1.12 h in shCtrl- and shHuR-expressing cells, respectively (Fig. 3F), indicating that this transcript is indeed stabilized by HuR.	complete CACAO 12232
	GO:0006606	protein import into nucleus	PMID:27609837^[1]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Mouse ELAVL1/Hua(Hur) Strikingly, in M2−/− cells with stable reduced expression of HuR, RA induced a discernible shift in the subcellular localization of CRABP2, but this shift did not culminate in nuclear import. Instead, CRABP2 accumulated around the nucleus and did not enter this compartment (Fig. 2A)	complete CACAO 12233
involved_in	GO:0070935	3'-UTR-mediated mRNA stabilization	PMID:27616329^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:27616329^[2]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0010494	cytoplasmic stress granule	PMID:27616329^[2]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0010494	cytoplasmic stress granule	PMID:27430620^[3]	ECO:0000314	direct assay evidence used in manual assertion		C	exists_during:(GO:0034599)	Seeded From UniProt	complete
enables	GO:0035198	miRNA binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q15717	F		Seeded From UniProt	complete
involved_in	GO:0060965	negative regulation of gene silencing by miRNA	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q15717	P		Seeded From UniProt	complete
involved_in	GO:0051260	protein homooligomerization	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q15717	P		Seeded From UniProt	complete
enables	GO:0003729	mRNA binding	PMID:17288565^[4]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0035925	mRNA 3'-UTR AU-rich region binding	PMID:17288565^[4]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:17288565^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:17288565^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q15717	C		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q15717	C		Seeded From UniProt	complete
enables	GO:0035925	mRNA 3'-UTR AU-rich region binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q15717	F		Seeded From UniProt	complete
part_of	GO:1990904	ribonucleoprotein complex	PMID:17971298^[5]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0035925	mRNA 3'-UTR AU-rich region binding	PMID:17971298^[5]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:2000036	regulation of stem cell population maintenance	PMID:24394384^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0070935	3'-UTR-mediated mRNA stabilization	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q15717	P		Seeded From UniProt	complete
involved_in	GO:0048255	mRNA stabilization	PMID:24394384^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0048255	mRNA stabilization	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q15717	P		Seeded From UniProt	complete
enables	GO:0017091	AU-rich element binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q15717	F		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q15717	C		Seeded From UniProt	complete
enables	GO:0003730	mRNA 3'-UTR binding	PMID:24394384^[6]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0003723	RNA binding	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q15717	F		Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	PMID:26554012^[7]	ECO:0006042	cell fractionation evidence used in manual assertion		C	part_of:(UBERON:0001950)	Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	PMID:26554012^[7]	ECO:0005589	confocal microscopy evidence used in manual assertion		C	part_of:(UBERON:0001950)	Seeded From UniProt	complete
part_of	GO:0098978	glutamatergic synapse	PMID:26554012^[7]	ECO:0000279	western blot evidence used in manual assertion		C	part_of:(UBERON:0001950)	Seeded From UniProt	complete
part_of	GO:0098794	postsynapse	PMID:26554012^[7]	ECO:0006042	cell fractionation evidence used in manual assertion		C	part_of:(GO:0098978) part_of:(UBERON:0000061) part_of:(UBERON:0001950)	Seeded From UniProt	complete
part_of	GO:0098794	postsynapse	PMID:26554012^[7]	ECO:0005589	confocal microscopy evidence used in manual assertion		C	part_of:(GO:0098978) part_of:(UBERON:0000061) part_of:(UBERON:0001950)	Seeded From UniProt	complete
part_of	GO:0098794	postsynapse	PMID:26554012^[7]	ECO:0000279	western blot evidence used in manual assertion		C	part_of:(GO:0098978) part_of:(UBERON:0000061) part_of:(UBERON:0001950)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0070935	3'-UTR-mediated mRNA stabilization	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q15717	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060965	negative regulation of gene silencing by miRNA	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q15717	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0051260	protein homooligomerization	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q15717	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048255	mRNA stabilization	PMID:21613615^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048255	mRNA stabilization	PMID:14976220^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048255	mRNA stabilization	PMID:21613615^[8]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q15717	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048255	mRNA stabilization	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q15717	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045727	positive regulation of translation	PMID:21613615^[8]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045727	positive regulation of translation	PMID:21613615^[8]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045727	positive regulation of translation	PMID:21613615^[8]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q15717	P		Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q15717	F		Seeded From UniProt	complete
enables	GO:0035925	mRNA 3'-UTR AU-rich region binding	PMID:23056314^[10]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q15717	F		Seeded From UniProt	complete
enables	GO:0035925	mRNA 3'-UTR AU-rich region binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q15717	F		Seeded From UniProt	complete
enables	GO:0035198	miRNA binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q15717	F		Seeded From UniProt	complete
enables	GO:0019901	protein kinase binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q15717	F		Seeded From UniProt	complete
enables	GO:0019901	protein kinase binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:1308649	F		Seeded From UniProt	complete
enables	GO:0017091	AU-rich element binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q15717	F		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q15717	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:17475777^[11]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0002372)	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q15717	C		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q15717	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:16168373^[12]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q15717	C		Seeded From UniProt	complete
enables	GO:0003730	mRNA 3'-UTR binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q15717	F		Seeded From UniProt	complete
enables	GO:0003730	mRNA 3'-UTR binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:1308649	F		Seeded From UniProt	complete
enables	GO:0003725	double-stranded RNA binding	PMID:21266579^[13]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q15717	F		Seeded From UniProt	complete
enables	GO:0003723	RNA binding	PMID:21613615^[8]	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q15717	F		Seeded From UniProt	complete
enables	GO:0003723	RNA binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q15717	F		Seeded From UniProt	complete
enables	GO:0019901	protein kinase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:B5DF91 ensembl:ENSRNOP00000001415	F		Seeded From UniProt	complete
enables	GO:0003730	mRNA 3'-UTR binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:B5DF91 ensembl:ENSRNOP00000001415	F		Seeded From UniProt	complete
involved_in	GO:0070935	3'-UTR-mediated mRNA stabilization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q15717 ensembl:ENSP00000385269	P		Seeded From UniProt	complete
involved_in	GO:0060965	negative regulation of gene silencing by miRNA	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q15717 ensembl:ENSP00000385269	P		Seeded From UniProt	complete
involved_in	GO:0051260	protein homooligomerization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q15717 ensembl:ENSP00000385269	P		Seeded From UniProt	complete
involved_in	GO:0048255	mRNA stabilization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q15717 ensembl:ENSP00000385269	P		Seeded From UniProt	complete
involved_in	GO:0045727	positive regulation of translation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q15717 ensembl:ENSP00000385269	P		Seeded From UniProt	complete
enables	GO:0042803	protein homodimerization activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q15717 ensembl:ENSP00000385269	F		Seeded From UniProt	complete
enables	GO:0035925	mRNA 3'-UTR AU-rich region binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q15717 ensembl:ENSP00000385269	F		Seeded From UniProt	complete
enables	GO:0035198	miRNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q15717 ensembl:ENSP00000385269	F		Seeded From UniProt	complete
enables	GO:0019901	protein kinase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q15717 ensembl:ENSP00000385269	F		Seeded From UniProt	complete
enables	GO:0017091	AU-rich element binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q15717 ensembl:ENSP00000385269	F		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q15717 ensembl:ENSP00000385269	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q15717 ensembl:ENSP00000385269	C		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q15717 ensembl:ENSP00000385269	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q15717 ensembl:ENSP00000385269	C		Seeded From UniProt	complete
enables	GO:0003730	mRNA 3'-UTR binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q15717 ensembl:ENSP00000385269	F		Seeded From UniProt	complete
enables	GO:0003725	double-stranded RNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q15717 ensembl:ENSP00000385269	F		Seeded From UniProt	complete
enables	GO:0003723	RNA binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q15717 ensembl:ENSP00000385269	F		Seeded From UniProt	complete
enables	GO:0003676	nucleic acid binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR000504 InterPro:IPR035979	F		Seeded From UniProt	complete
enables	GO:0003723	RNA binding	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR002343 InterPro:IPR006548	F		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963 UniProtKB-SubCell:SL-0086	C		Seeded From UniProt	complete
enables	GO:0003723	RNA binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0694	F		Seeded From UniProt	complete
part_of	GO:0010494	cytoplasmic stress granule	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0496	C		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 Zhang, W et al. (2016) RNA-binding protein HuR regulates nuclear import of protein. J. Cell. Sci. 129 4025-4033 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 Nishino, T et al. (2016) Antagonizing effect of CLPABP on the function of HuR as a regulator of ARE-containing leptin mRNA stability and the effect of its depletion on obesity in old male mouse. Biochim. Biophys. Acta 1861 1816-1827 PubMed GONUTS page
↑ Mahboubi, H et al. (2016) AMP Kinase Activation Alters Oxidant-Induced Stress Granule Assembly by Modulating Cell Signaling and Microtubule Organization. Mol. Pharmacol. 90 460-8 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 Lin, NY et al. (2007) Regulation of tristetraprolin during differentiation of 3T3-L1 preadipocytes. FEBS J. 274 867-78 PubMed GONUTS page
↑ ^5.0 ^5.1 Lin, NY et al. (2008) Modulation of immediate early gene expression by tristetraprolin in the differentiation of 3T3-L1 cells. Biochem. Biophys. Res. Commun. 365 69-74 PubMed GONUTS page
↑ ^6.0 ^6.1 ^6.2 Wang, Y et al. (2014) N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells. Nat. Cell Biol. 16 191-8 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 ^7.3 ^7.4 ^7.5 Suhl, JA et al. (2015) A 3' untranslated region variant in FMR1 eliminates neuronal activity-dependent translation of FMRP by disrupting binding of the RNA-binding protein HuR. Proc. Natl. Acad. Sci. U.S.A. 112 E6553-61 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 ^8.3 ^8.4 ^8.5 Stellato, C et al. (2011) Coordinate regulation of GATA-3 and Th2 cytokine gene expression by the RNA-binding protein HuR. J. Immunol. 187 441-9 PubMed GONUTS page
↑ Raineri, I et al. (2004) Roles of AUF1 isoforms, HuR and BRF1 in ARE-dependent mRNA turnover studied by RNA interference. Nucleic Acids Res. 32 1279-88 PubMed GONUTS page
↑ Miyashita, H et al. (2012) Angiogenesis inhibitor vasohibin-1 enhances stress resistance of endothelial cells via induction of SOD2 and SIRT1. PLoS ONE 7 e46459 PubMed GONUTS page
↑ van der Giessen, K & Gallouzi, IE (2007) Involvement of transportin 2-mediated HuR import in muscle cell differentiation. Mol. Biol. Cell 18 2619-29 PubMed GONUTS page
↑ Katsanou, V et al. (2005) HuR as a negative posttranscriptional modulator in inflammation. Mol. Cell 19 777-89 PubMed GONUTS page
↑ Watanabe, A et al. (2011) Raftlin is involved in the nucleocapture complex to induce poly(I:C)-mediated TLR3 activation. J. Biol. Chem. 286 10702-11 PubMed GONUTS page

[PMID:27609837-1] 1.0 ^1.1 ^1.2 ^1.3 Zhang, W et al. (2016) RNA-binding protein HuR regulates nuclear import of protein. J. Cell. Sci. 129 4025-4033 PubMed GONUTS page

[PMID:27616329-2] 2.0 ^2.1 ^2.2 Nishino, T et al. (2016) Antagonizing effect of CLPABP on the function of HuR as a regulator of ARE-containing leptin mRNA stability and the effect of its depletion on obesity in old male mouse. Biochim. Biophys. Acta 1861 1816-1827 PubMed GONUTS page

[PMID:27430620-3] Mahboubi, H et al. (2016) AMP Kinase Activation Alters Oxidant-Induced Stress Granule Assembly by Modulating Cell Signaling and Microtubule Organization. Mol. Pharmacol. 90 460-8 PubMed GONUTS page

[PMID:17288565-4] 4.0 ^4.1 ^4.2 ^4.3 Lin, NY et al. (2007) Regulation of tristetraprolin during differentiation of 3T3-L1 preadipocytes. FEBS J. 274 867-78 PubMed GONUTS page

[PMID:17971298-5] 5.0 ^5.1 Lin, NY et al. (2008) Modulation of immediate early gene expression by tristetraprolin in the differentiation of 3T3-L1 cells. Biochem. Biophys. Res. Commun. 365 69-74 PubMed GONUTS page

[PMID:24394384-6] 6.0 ^6.1 ^6.2 Wang, Y et al. (2014) N6-methyladenosine modification destabilizes developmental regulators in embryonic stem cells. Nat. Cell Biol. 16 191-8 PubMed GONUTS page

[PMID:26554012-7] 7.0 ^7.1 ^7.2 ^7.3 ^7.4 ^7.5 Suhl, JA et al. (2015) A 3' untranslated region variant in FMR1 eliminates neuronal activity-dependent translation of FMRP by disrupting binding of the RNA-binding protein HuR. Proc. Natl. Acad. Sci. U.S.A. 112 E6553-61 PubMed GONUTS page

[PMID:21613615-8] 8.0 ^8.1 ^8.2 ^8.3 ^8.4 ^8.5 Stellato, C et al. (2011) Coordinate regulation of GATA-3 and Th2 cytokine gene expression by the RNA-binding protein HuR. J. Immunol. 187 441-9 PubMed GONUTS page

[PMID:14976220-9] Raineri, I et al. (2004) Roles of AUF1 isoforms, HuR and BRF1 in ARE-dependent mRNA turnover studied by RNA interference. Nucleic Acids Res. 32 1279-88 PubMed GONUTS page

[PMID:23056314-10] Miyashita, H et al. (2012) Angiogenesis inhibitor vasohibin-1 enhances stress resistance of endothelial cells via induction of SOD2 and SIRT1. PLoS ONE 7 e46459 PubMed GONUTS page

[PMID:17475777-11] van der Giessen, K & Gallouzi, IE (2007) Involvement of transportin 2-mediated HuR import in muscle cell differentiation. Mol. Biol. Cell 18 2619-29 PubMed GONUTS page

[PMID:16168373-12] Katsanou, V et al. (2005) HuR as a negative posttranscriptional modulator in inflammation. Mol. Cell 19 777-89 PubMed GONUTS page

[PMID:21266579-13] Watanabe, A et al. (2011) Raftlin is involved in the nucleocapture complex to induce poly(I:C)-mediated TLR3 activation. J. Biol. Chem. 286 10702-11 PubMed GONUTS page

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MOUSE:ELAV1

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