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MOUSE:EFGM

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Gfm1 (synonyms: Efg, Efg1, Gfm)
Protein Name(s) Elongation factor G, mitochondrial (ECO:0000255 with HAMAP-Rule:MF_03061)

EF-Gmt (ECO:0000255 with HAMAP-Rule:MF_03061) Elongation factor G 1, mitochondrial (ECO:0000255 with HAMAP-Rule:MF_03061) mEF-G 1 (ECO:0000255 with HAMAP-Rule:MF_03061) Elongation factor G1 (ECO:0000255 with HAMAP-Rule:MF_03061)

External Links
UniProt Q8K0D5
EMBL AF315511
BC013093
BC031772
CCDS CCDS38449.1
RefSeq NP_613057.2
UniGene Mm.122466
ProteinModelPortal Q8K0D5
SMR Q8K0D5
IntAct Q8K0D5
MINT MINT-4094092
PhosphoSite Q8K0D5
MaxQB Q8K0D5
PaxDb Q8K0D5
PRIDE Q8K0D5
Ensembl ENSMUST00000077271
GeneID 28030
KEGG mmu:28030
UCSC uc008plm.2
CTD 85476
MGI MGI:107339
eggNOG COG0480
GeneTree ENSGT00550000074911
HOGENOM HOG000231585
InParanoid Q8K0D5
KO K02355
OMA AFQLAAI
OrthoDB EOG7VDXNM
PhylomeDB Q8K0D5
TreeFam TF105631
Reactome REACT_270125
UniPathway UPA00345
ChiTaRS Gfm1
NextBio 306550
PRO PR:Q8K0D5
Proteomes UP000000589
Bgee Q8K0D5
CleanEx MM_GFM1
ExpressionAtlas Q8K0D5
Genevestigator Q8K0D5
GO GO:0005739
GO:0005525
GO:0003924
GO:0044822
GO:0003746
GO:0006184
GO:0070125
Gene3D 3.30.230.10
3.30.70.240
3.40.50.300
HAMAP MF_00054_B
InterPro IPR000795
IPR009022
IPR000640
IPR027417
IPR020568
IPR014721
IPR005225
IPR009000
IPR004540
IPR005517
IPR004161
Pfam PF00679
PF14492
PF03764
PF00009
PF03144
PRINTS PR00315
SMART SM00838
SM00889
SUPFAM SSF50447
SSF52540
SSF54211
SSF54980
TIGRFAMs TIGR00484
TIGR00231
PROSITE PS00301
PS51722

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0003746

translation elongation factor activity

PMID:11374907[1]

ECO:0000247

UniProtKB:Q07803 UniProtKB:Q96RP9


F

Fig: 1

complete

involved_in

GO:0070125

mitochondrial translational elongation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q96RP9

P

Seeded From UniProt

complete

enables

GO:0003924

GTPase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q96RP9

F

Seeded From UniProt

complete

enables

GO:0003746

translation elongation factor activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q96RP9

F

Seeded From UniProt

complete

involved_in

GO:0070125

mitochondrial translational elongation

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000563009
UniProtKB:Q96RP9

P

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

FB:FBgn0263133
PANTHER:PTN000563009
SGD:S000004059
TAIR:locus:2055611
TAIR:locus:2825721
UniProtKB:Q8I592

C

Seeded From UniProt

complete

enables

GO:0003924

GTPase activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002462392
UniProtKB:Q96RP9

F

Seeded From UniProt

complete

enables

GO:0003746

translation elongation factor activity

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN002462392
UniProtKB:Q96RP9

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0070125

mitochondrial translational elongation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q96RP9

P

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

PMID:18614015[3]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

PMID:14651853[4]

ECO:0007005

high throughput direct assay evidence used in manual assertion

C

part_of:(EMAPA:16846)|part_of:(EMAPA:16894)|part_of:(EMAPA:17373)|part_of:(EMAPA:16105)

Seeded From UniProt

complete

enables

GO:0003924

GTPase activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q96RP9

F

Seeded From UniProt

complete

enables

GO:0003746

translation elongation factor activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q96RP9

F

Seeded From UniProt

complete

involved_in

GO:0070125

mitochondrial translational elongation

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q96RP9
ensembl:ENSP00000264263

P

Seeded From UniProt

complete

enables

GO:0003924

GTPase activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q96RP9
ensembl:ENSP00000264263

F

Seeded From UniProt

complete

enables

GO:0003746

translation elongation factor activity

GO_REF:0000107

ECO:0000265

sequence orthology evidence used in automatic assertion

UniProtKB:Q96RP9
ensembl:ENSP00000264263

F

Seeded From UniProt

complete

enables

GO:0003746

translation elongation factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004540

F

Seeded From UniProt

complete

enables

GO:0003924

GTPase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000795

F

Seeded From UniProt

complete

enables

GO:0005525

GTP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000795
InterPro:IPR004161
InterPro:IPR004540
InterPro:IPR005225
InterPro:IPR005517

F

Seeded From UniProt

complete

involved_in

GO:0006414

translational elongation

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004540

P

Seeded From UniProt

complete

involved_in

GO:0070125

mitochondrial translational elongation

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000369139

P

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000369139

C

Seeded From UniProt

complete

enables

GO:0003746

translation elongation factor activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000369139

F

Seeded From UniProt

complete

enables

GO:0005525

GTP binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000369139

F

Seeded From UniProt

complete

enables

GO:0003924

GTPase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000369139

F

Seeded From UniProt

complete

involved_in

GO:0006412

translation

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0648

P

Seeded From UniProt

complete

enables

GO:0005525

GTP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0342

F

Seeded From UniProt

complete

part_of

GO:0005739

mitochondrion

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0496
UniProtKB-SubCell:SL-0173

C

Seeded From UniProt

complete

enables

GO:0003746

translation elongation factor activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0251

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

involved_in

GO:0006414

translational elongation

GO_REF:0000037
GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0251
UniPathway:UPA00345

P

Seeded From UniProt

complete

edit table

Notes

References

See Help:References for how to manage references in GONUTS.

  1. ↑ Gao, J et al. (2001) Cloning and characterization of human and mouse mitochondrial elongation factor G, GFM and Gfm, and mapping of GFM to human chromosome 3q25.1-q26.2. Genomics 74 109-14 PubMed GONUTS page
  2. ↑ 2.0 2.1 2.2 2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
  3. ↑ Pagliarini, DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134 112-23 PubMed GONUTS page
  4. ↑ Mootha, VK et al. (2003) Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell 115 629-40 PubMed GONUTS page
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