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MOUSE:DPYL1
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Crmp1 (synonyms: Dpysl1, Ulip3) | |
| Protein Name(s) | Dihydropyrimidinase-related protein 1
DRP-1 Collapsin response mediator protein 1 CRMP-1 Unc-33-like phosphoprotein 3 ULIP-3 | |
| External Links | ||
| UniProt | P97427 | |
| EMBL | U72875 Y09080 AB006714 BC031738 | |
| CCDS | CCDS39075.1 | |
| RefSeq | NP_031791.3 | |
| UniGene | Mm.290995 | |
| PDB | 1KCX | |
| PDBsum | 1KCX | |
| ProteinModelPortal | P97427 | |
| SMR | P97427 | |
| BioGrid | 198890 | |
| IntAct | P97427 | |
| MINT | MINT-4093514 | |
| MEROPS | M38.974 | |
| PhosphoSite | P97427 | |
| MaxQB | P97427 | |
| PaxDb | P97427 | |
| PRIDE | P97427 | |
| Ensembl | ENSMUST00000031004 | |
| GeneID | 12933 | |
| KEGG | mmu:12933 | |
| UCSC | uc008xfm.1 | |
| CTD | 1400 | |
| MGI | MGI:107793 | |
| eggNOG | COG0044 | |
| GeneTree | ENSGT00760000119241 | |
| HOGENOM | HOG000219145 | |
| HOVERGEN | HBG000806 | |
| InParanoid | P97427 | |
| PhylomeDB | P97427 | |
| Reactome | REACT_244852 | |
| ChiTaRS | Crmp1 | |
| EvolutionaryTrace | P97427 | |
| NextBio | 282604 | |
| PRO | PR:P97427 | |
| Proteomes | UP000000589 | |
| Bgee | P97427 | |
| CleanEx | MM_CRMP1 | |
| ExpressionAtlas | P97427 | |
| Genevestigator | P97427 | |
| GO | GO:0005737 GO:0030425 GO:0005815 GO:0043025 GO:0005819 GO:0016812 GO:0051219 GO:0006208 | |
| Gene3D | 2.30.40.10 | |
| InterPro | IPR006680 IPR011778 IPR011059 | |
| Pfam | PF01979 | |
| SUPFAM | SSF51338 | |
| TIGRFAMs | TIGR02033 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0007616 |
long-term memory |
ECO:0000315 |
P |
Figure 3B: Barnes maze test |
complete | |||||
|
involved_in |
GO:0071526 |
semaphorin-plexin signaling pathway |
ECO:0000316 |
genetic interaction evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0071526 |
semaphorin-plexin signaling pathway |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
colocalizes_with |
GO:0031941 |
filamentous actin |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
exists_during:(GO:0071526) |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0030426 |
growth cone |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0051219 |
phosphoprotein binding |
ECO:0000353 |
physical interaction evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:1904530 |
negative regulation of actin filament binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0043025 |
neuronal cell body |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0031005 |
filamin binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0031005 |
filamin binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2407 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0030496 |
midbody |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030425 |
dendrite |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0010977 |
negative regulation of neuron projection development |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005813 |
centrosome |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2407 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
RGD:2407 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0000226 |
microtubule cytoskeleton organization |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007399 |
nervous system development |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007411 |
axon guidance |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016787 |
hydrolase activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0016810 |
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005856 |
cytoskeleton |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005815 |
microtubule organizing center |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005819 |
spindle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Yamashita, N et al. (2013) Mice lacking collapsin response mediator protein 1 manifest hyperactivity, impaired learning and memory, and impaired prepulse inhibition. Front Behav Neurosci 7 216 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 Nakamura, F et al. (2014) Amino- and carboxyl-terminal domains of Filamin-A interact with CRMP1 to mediate Sema3A signalling. Nat Commun 5 5325 PubMed GONUTS page
- ↑ Fukada, M et al. (2000) Molecular characterization of CRMP5, a novel member of the collapsin response mediator protein family. J. Biol. Chem. 275 37957-65 PubMed GONUTS page
- ↑ 4.0 4.1 Bretin, S et al. (2005) Differential expression of CRMP1, CRMP2A, CRMP2B, and CRMP5 in axons or dendrites of distinct neurons in the mouse brain. J. Comp. Neurol. 486 1-17 PubMed GONUTS page
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