GONUTS has been updated to MW1.31 Most things seem to be working but be sure to report problems.
MOUSE:DLX3
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Dlx3 | |
| Protein Name(s) | Homeobox protein DLX-3 | |
| External Links | ||
| UniProt | Q64205 | |
| EMBL | S81932 BC058852 | |
| CCDS | CCDS25272.1 | |
| RefSeq | NP_034185.1 | |
| UniGene | Mm.5194 | |
| ProteinModelPortal | Q64205 | |
| SMR | Q64205 | |
| IntAct | Q64205 | |
| MINT | MINT-4093163 | |
| PhosphoSite | Q64205 | |
| PaxDb | Q64205 | |
| PRIDE | Q64205 | |
| Ensembl | ENSMUST00000092768 | |
| GeneID | 13393 | |
| KEGG | mmu:13393 | |
| UCSC | uc007kzy.2 | |
| CTD | 1747 | |
| MGI | MGI:94903 | |
| eggNOG | NOG299102 | |
| HOGENOM | HOG000231940 | |
| HOVERGEN | HBG005493 | |
| InParanoid | Q64205 | |
| KO | K09315 | |
| OMA | SWYHTQN | |
| OrthoDB | EOG70W3F8 | |
| PhylomeDB | Q64205 | |
| TreeFam | TF350606 | |
| NextBio | 283764 | |
| PRO | PR:Q64205 | |
| Proteomes | UP000000589 | |
| Bgee | Q64205 | |
| CleanEx | MM_DLX3 | |
| ExpressionAtlas | Q64205 | |
| Genevestigator | Q64205 | |
| GO | GO:0005634 GO:0003682 GO:0001077 GO:0043565 GO:0001568 GO:0071895 GO:0042475 GO:0001890 GO:0045944 | |
| Gene3D | 1.10.10.60 | |
| InterPro | IPR022135 IPR017970 IPR001356 IPR020479 IPR009057 IPR000047 | |
| Pfam | PF12413 PF00046 | |
| PRINTS | PR00024 PR00031 | |
| SMART | SM00389 | |
| SUPFAM | SSF46689 | |
| PROSITE | PS00027 PS50071 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0071895 |
odontoblast differentiation |
ECO:0000315 |
P |
Fig. 4 and Fig. 5 |
complete | |||||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0071895 |
odontoblast differentiation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0043565 |
sequence-specific DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:101926 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030855 |
epithelial cell differentiation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:94903 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030154 |
cell differentiation |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:94903 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006357 |
regulation of transcription by RNA polymerase II |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:101926 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0000157 |
C |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:1919200 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0000978 |
RNA polymerase II proximal promoter sequence-specific DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
MGI:MGI:101926 |
F |
Seeded From UniProt |
complete | ||
|
acts_upstream_of_or_within |
GO:0071895 |
odontoblast differentiation |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2386570,MGI:MGI:3813133 |
P |
occurs_in:(EMAPA:32897) |
Seeded From UniProt |
complete | |
|
acts_upstream_of_or_within |
GO:0042475 |
odontogenesis of dentin-containing tooth |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2386570,MGI:MGI:3813133 |
P |
has_participant:(EMAPA:32897) |
Seeded From UniProt |
complete | |
|
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003682 |
chromatin binding |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0001890 |
placenta development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2155443 |
P |
results_in_development_of:(EMAPA:16042)|results_in_development_of:(EMAPA:16370) |
Seeded From UniProt |
complete | |
|
acts_upstream_of_or_within |
GO:0001568 |
blood vessel development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
MGI:MGI:2155443 |
P |
occurs_in:(EMAPA:16370) |
Seeded From UniProt |
complete | |
|
enables |
GO:0001228 |
DNA-binding transcription activator activity, RNA polymerase II-specific |
ECO:0000314 |
direct assay evidence used in manual assertion |
F |
occurs_at:(SO:0001668) |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0045944 |
positive regulation of transcription by RNA polymerase II |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0001228 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:O60479 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
InterPro:IPR000047 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0043565 |
sequence-specific DNA binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007275 |
multicellular organism development |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Duverger, O et al. (2012) Neural crest deletion of Dlx3 leads to major dentin defects through down-regulation of Dspp. J. Biol. Chem. 287 12230-40 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
- ↑ Nishiyama, A et al. (2009) Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors. Cell Stem Cell 5 420-33 PubMed GONUTS page
- ↑ 4.0 4.1 Morasso, MI et al. (1999) Placental failure in mice lacking the homeobox gene Dlx3. Proc. Natl. Acad. Sci. U.S.A. 96 162-7 PubMed GONUTS page
d
g
m
p
r
