MOUSE:CTND2

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Ctnnd2 (synonyms: Catnd2, Nprap)
Protein Name(s)	Catenin delta-2 Neural plakophilin-related ARM-repeat protein NPRAP Neurojungin
External Links
UniProt	O35927
EMBL	U90331 BC138260 BC138261
PIR	T42209
RefSeq	NP_032755.2
UniGene	Mm.321648
ProteinModelPortal	O35927
SMR	O35927
BioGrid	201832
IntAct	O35927
MINT	MINT-4092555
PhosphoSite	O35927
MaxQB	O35927
PaxDb	O35927
PRIDE	O35927
GeneID	18163
KEGG	mmu:18163
CTD	1501
MGI	MGI:1195966
eggNOG	NOG276924
HOGENOM	HOG000231863
HOVERGEN	HBG004284
InParanoid	O35927
PhylomeDB	O35927
ChiTaRS	Ctnnd2
NextBio	293442
PRO	PR:O35927
Proteomes	UP000000589
Bgee	O35927
CleanEx	MM_CTNND2
ExpressionAtlas	O35927
Genevestigator	O35927
GO	GO:0005912 GO:0043005 GO:0005634 GO:0014069 GO:0007612 GO:0001763 GO:0007275 GO:0048167 GO:0006355 GO:0016337 GO:0006351
Gene3D	1.25.10.10
InterPro	IPR011989 IPR016024 IPR000225 IPR028435
PANTHER	PTHR10372
Pfam	PF00514
SMART	SM00185
SUPFAM	SSF48371
PROSITE	PS50176

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Notes	Status
part_of	GO:0043204	perikaryon	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9UQB3	C	Seeded From UniProt	complete
involved_in	GO:0098609	cell-cell adhesion	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:105100 MGI:MGI:1914701 PANTHER:PTN000822184	P	Seeded From UniProt	complete
involved_in	GO:0060997	dendritic spine morphogenesis	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000042913 UniProtKB:Q9UQB3	P	Seeded From UniProt	complete
involved_in	GO:0050808	synapse organization	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000042913 UniProtKB:Q9UQB3	P	Seeded From UniProt	complete
enables	GO:0045296	cadherin binding	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000822184 UniProtKB:O60716 WB:WBGene00002175	F	Seeded From UniProt	complete
part_of	GO:0014069	postsynaptic density	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1195966 PANTHER:PTN000042913 RGD:620734	C	Seeded From UniProt	complete
involved_in	GO:0007043	cell-cell junction assembly	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:109281 PANTHER:PTN000822184	P	Seeded From UniProt	complete
part_of	GO:0005913	cell-cell adherens junction	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:105100 PANTHER:PTN000822184 WB:WBGene00002175	C	Seeded From UniProt	complete
part_of	GO:0005911	cell-cell junction	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:1914701 PANTHER:PTN000822184 UniProtKB:O60716 UniProtKB:Q99569	C	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:105100 MGI:MGI:109620 PANTHER:PTN000822184 RGD:1305643 UniProtKB:O60716 UniProtKB:Q13835 UniProtKB:Q99569 UniProtKB:Q99959 UniProtKB:Q9Y446	C	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0260799 MGI:MGI:105100 MGI:MGI:109620 PANTHER:PTN000822184 RGD:1305643 UniProtKB:O60716 UniProtKB:Q99569	C	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:21873635^[1]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:105100 MGI:MGI:109620 PANTHER:PTN000822184 RGD:1305643 RGD:620734 UniProtKB:O60716 UniProtKB:Q13835	C	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060997	dendritic spine morphogenesis	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9UQB3	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060828	regulation of canonical Wnt signaling pathway	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9UQB3	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0050808	synapse organization	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9UQB3	P	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048167	regulation of synaptic plasticity	PMID:15380068^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3056606	P	Seeded From UniProt	complete
part_of	GO:0043204	perikaryon	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9UQB3	C	Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:620734	C	Seeded From UniProt	complete
part_of	GO:0014069	postsynaptic density	PMID:17114649^[3]	ECO:0000314	direct assay evidence used in manual assertion		C	Seeded From UniProt	complete
part_of	GO:0014069	postsynaptic density	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:620734	C	Seeded From UniProt	complete
enables	GO:0008013	beta-catenin binding	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q9UQB3	F	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007612	learning	PMID:15380068^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:3056606	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:620734	C	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001763	morphogenesis of a branching structure	PMID:17097608^[4]	ECO:0000314	direct assay evidence used in manual assertion		P	Seeded From UniProt	complete
involved_in	GO:0098609	cell-cell adhesion	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR028435	P	Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C	Seeded From UniProt	complete
involved_in	GO:0007155	cell adhesion	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0130	P	Seeded From UniProt	complete
involved_in	GO:0007275	multicellular organism development	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0217	P	Seeded From UniProt	complete
part_of	GO:0042995	cell projection	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0966	C	Seeded From UniProt	complete
part_of	GO:0030054	cell junction	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0965	C	Seeded From UniProt	complete
part_of	GO:0005912	adherens junction	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0009	C	Seeded From UniProt	complete
part_of	GO:0030425	dendrite	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0283	C	Seeded From UniProt	complete
part_of	GO:0043204	perikaryon	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0197	C	Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.00 ^1.01 ^1.02 ^1.03 ^1.04 ^1.05 ^1.06 ^1.07 ^1.08 ^1.09 ^1.10 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ ^2.0 ^2.1 Israely, I et al. (2004) Deletion of the neuron-specific protein delta-catenin leads to severe cognitive and synaptic dysfunction. Curr. Biol. 14 1657-63 PubMed GONUTS page
↑ Munton, RP et al. (2007) Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Mol. Cell Proteomics 6 283-93 PubMed GONUTS page
↑ Kim, JS et al. (2006) Presenilin-1 inhibits delta-catenin-induced cellular branching and promotes delta-catenin processing and turnover. Biochem. Biophys. Res. Commun. 351 903-8 PubMed GONUTS page

[PMID:21873635-1] 1.00 ^1.01 ^1.02 ^1.03 ^1.04 ^1.05 ^1.06 ^1.07 ^1.08 ^1.09 ^1.10 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:15380068-2] 2.0 ^2.1 Israely, I et al. (2004) Deletion of the neuron-specific protein delta-catenin leads to severe cognitive and synaptic dysfunction. Curr. Biol. 14 1657-63 PubMed GONUTS page

[PMID:17114649-3] Munton, RP et al. (2007) Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Mol. Cell Proteomics 6 283-93 PubMed GONUTS page

[PMID:17097608-4] Kim, JS et al. (2006) Presenilin-1 inhibits delta-catenin-induced cellular branching and promotes delta-catenin processing and turnover. Biochem. Biophys. Res. Commun. 351 903-8 PubMed GONUTS page

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MOUSE:CTND2

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