MOUSE:CNTN2

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Cntn2 (synonyms: Tax)
Protein Name(s)	Contactin-2 Axonal glycoprotein TAG-1 Axonin-1 Transient axonal glycoprotein 1 TAX-1
External Links
UniProt	Q61330
EMBL	BC066106 BC053033 X81365
CCDS	CCDS15288.1
RefSeq	NP_796103.2 XP_006529424.1 XP_006529425.1
UniGene	Mm.260861
ProteinModelPortal	Q61330
SMR	Q61330
BioGrid	203974
IntAct	Q61330
STRING	10090.ENSMUSP00000083707
PhosphoSite	Q61330
MaxQB	Q61330
PaxDb	Q61330
PRIDE	Q61330
Ensembl	ENSMUST00000086521
GeneID	21367
KEGG	mmu:21367
UCSC	uc007cpa.1
CTD	6900
MGI	MGI:104518
eggNOG	NOG293951
GeneTree	ENSGT00760000118840
HOGENOM	HOG000059617
HOVERGEN	HBG051047
InParanoid	Q61330
KO	K06760
OMA	ECFAFGN
OrthoDB	EOG7J17Z5
PhylomeDB	Q61330
TreeFam	TF351103
Reactome	REACT_219680 REACT_230679 REACT_236183
NextBio	300578
PRO	PR:Q61330
Proteomes	UP000000589
Bgee	Q61330
CleanEx	MM_CNTN2
ExpressionAtlas	Q61330
Genevestigator	Q61330
GO	GO:0031225 GO:0030424 GO:0009986 GO:0044224 GO:0043209 GO:0043005 GO:0043025 GO:0033268 GO:0005886 GO:0030246 GO:0001948 GO:0043621 GO:0007628 GO:0007411 GO:0007413 GO:0007155 GO:0034613 GO:0022010 GO:0021853 GO:0045163 GO:0071206 GO:0007612 GO:0000226 GO:0045665 GO:0001764 GO:0031175 GO:0060168 GO:0010954 GO:0097090 GO:0071205 GO:0031623 GO:0048710 GO:0031133 GO:0010769 GO:0048168
Gene3D	2.60.40.10
InterPro	IPR003961 IPR007110 IPR013783 IPR013098 IPR003599 IPR003598
Pfam	PF00041 PF07679
SMART	SM00060 SM00409 SM00408
SUPFAM	SSF49265
PROSITE	PS50853 PS50835

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
	GO:0071205	protein localization to juxtaparanode region of axon	PMID:20962216^[1]	ECO:0000315			P		Figure 6 and 7	complete CACAO 4334
involved_in	GO:0071206	establishment of protein localization to juxtaparanode region of axon	PMID:12975355^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0045163	clustering of voltage-gated potassium channels	PMID:12963709^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0044224	juxtaparanode region of axon	PMID:12963709^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0043209	myelin sheath	PMID:12963709^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0071205	protein localization to juxtaparanode region of axon	PMID:12963709^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0033268	node of Ranvier	PMID:12963709^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
colocalizes_with	GO:0008076	voltage-gated potassium channel complex	PMID:12975355^[2]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0097090	presynaptic membrane organization	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q02246	P		Seeded From UniProt	complete
part_of	GO:0099025	anchored component of postsynaptic membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q02246	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0097090	presynaptic membrane organization	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:Q02246	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0071205	protein localization to juxtaparanode region of axon	PMID:20962216^[1]	ECO:0000316	genetic interaction evidence used in manual assertion	UniProtKB:P22063	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0071205	protein localization to juxtaparanode region of axon	PMID:19109503^[4]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2677610	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0071205	protein localization to juxtaparanode region of axon	PMID:18760366^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2181052	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0060168	positive regulation of adenosine receptor signaling pathway	PMID:11178983^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2181052	P	regulates_o_occurs_in:(EMAPA:32845) regulates_o_occurs_in:(CL:0000117)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048710	regulation of astrocyte differentiation	PMID:18650339^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2181052	P	occurs_in:(EMAPA:17846) regulates_o_results_in_acquisition_of_features_of:(CL:0000127)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0048168	regulation of neuronal synaptic plasticity	PMID:11178983^[6]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2181052	P	regulates_o_occurs_in:(EMAPA:32845) regulates_o_has_participant:(CL:0000117)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0045665	negative regulation of neuron differentiation	PMID:18278038^[8]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:88059	P	occurs_in:(EMAPA:16913) regulates_o_results_in_acquisition_of_features_of:(CL:0000117)	Seeded From UniProt	complete
part_of	GO:0045202	synapse	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3821	C		Seeded From UniProt	complete
enables	GO:0043621	protein self-association	PMID:18550718^[9]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q61330	F		Seeded From UniProt	complete
part_of	GO:0043025	neuronal cell body	PMID:8089271^[10]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	PMID:18650339^[7]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:17168) part_of:(CL:0000740)\|part_of:(EMAPA:18590) part_of:(CL:0000740)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0031623	receptor internalization	PMID:18550718^[9]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0031175	neuron projection development	PMID:19458237^[11]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:105980 MGI:MGI:1914047 MGI:MGI:88323	P	occurs_in:(EMAPA:17787) occurs_in:(CL:0000540)\|occurs_in:(EMAPA:16668) occurs_in:(CL:0000540)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0031133	regulation of axon diameter	PMID:18650339^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2181052	P	regulates_o_has_participant:(EMAPA:17846) regulates_o_has_participant:(CL:0000540)	Seeded From UniProt	complete
part_of	GO:0030424	axon	PMID:8089271^[10]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:16525) part_of:(CL:0000100)\|part_of:(EMAPA:16525) part_of:(CL:0000100)\|part_of:(EMAPA:17577) part_of:(CL:0000100)\|part_of:(EMAPA:16668) part_of:(CL:0000540)\|part_of:(EMAPA:16668) part_of:(CL:0000540)\|part_of:(EMAPA:16668) part_of:(CL:0000540)\|part_of:(EMAPA:16668) part_of:(CL:0000540)\|part_of:(EMAPA:16668) part_of:(CL:0000540)\|part_of:(EMAPA:16668) part_of:(CL:0000540)\|part_of:(EMAPA:16668) part_of:(CL:0000540)\|part_of:(EMAPA:16668) part_of:(CL:0000540)\|part_of:(EMAPA:16989) part_of:(CL:0000540)\|part_of:(EMAPA:16989) part_of:(CL:0000540)\|part_of:(EMAPA:16989) part_of:(CL:0000540)\|part_of:(EMAPA:17577) part_of:(CL:0000540)\|part_of:(EMAPA:25149) part_of:(CL:0000540)\|part_of:(EMAPA:36513) part_of:(CL:0000540)\|part_of:(EMAPA:16800) part_of:(CL:0000540)\|part_of:(EMAPA:17606) part_of:(CL:0000540)\|part_of:(EMAPA:17168) part_of:(CL:0000540)\|part_of:(EMAPA:16659) part_of:(CL:0000117)\|part_of:(EMAPA:16659) part_of:(CL:0000117)\|part_of:(EMAPA:17264) part_of:(CL:0000117)\|part_of:(EMAPA:17264) part_of:(CL:0000117)\|part_of:(EMAPA:17576) part_of:(CL:0000117)\|part_of:(EMAPA:17576) part_of:(CL:0000117)\|part_of:(EMAPA:17576) part_of:(CL:0000117)\|part_of:(EMAPA:17576) part_of:(CL:0000117)\|part_of:(EMAPA:17576) part_of:(CL:0000117)\|part_of:(EMAPA:16478) part_of:(CL:0000117)\|part_of:(EMAPA:17074) part_of:(CL:0000117)\|part_of:(EMAPA:17074) part_of:(CL:0000117)\|part_of:(EMAPA:17787) part_of:(CL:0000117)\|part_of:(EMAPA:17787) part_of:(CL:0000117)\|part_of:(EMAPA:17787) part_of:(CL:0000117)\|part_of:(EMAPA:17787) part_of:(CL:0000117)\|part_of:(EMAPA:17787) part_of:(CL:0000117)\|part_of:(EMAPA:17078) part_of:(CL:0000117)\|part_of:(EMAPA:17078) part_of:(CL:0000117)\|part_of:(EMAPA:17544) part_of:(CL:0000117)\|part_of:(EMAPA:17544) part_of:(CL:0000117)\|part_of:(EMAPA:17544) part_of:(CL:0000117)\|part_of:(EMAPA:17797) part_of:(CL:0000117)\|part_of:(EMAPA:17550) part_of:(CL:0000117)\|part_of:(EMAPA:18591) part_of:(CL:0000117)\|part_of:(EMAPA:17846) part_of:(CL:0000117)\|part_of:(EMAPA:17797) part_of:(CL:0000117)\|part_of:(EMAPA:17545) part_of:(CL:0000117)\|part_of:(EMAPA:17550) part_of:(CL:0000117)\|part_of:(EMAPA:18591) part_of:(CL:0000117)\|part_of:(EMAPA:17846) part_of:(CL:0000117)\|part_of:(EMAPA:16910) part_of:(CL:0000117)\|part_of:(EMAPA:16910) part_of:(CL:0000117)\|part_of:(EMAPA:32870) part_of:(CL:0000117)\|part_of:(EMAPA:32869) part_of:(CL:0000117)\|part_of:(EMAPA:35547) part_of:(CL:0000117)\|part_of:(EMAPA:35437) part_of:(CL:0000117)\|part_of:(EMAPA:32845) part_of:(CL:0000117)\|part_of:(EMAPA:17575) part_of:(CL:0000117)	Seeded From UniProt	complete
part_of	GO:0030424	axon	PMID:18650339^[7]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:17846) part_of:(CL:0000540)\|part_of:(EMAPA:17846) part_of:(CL:0000540)	Seeded From UniProt	complete
part_of	GO:0030424	axon	PMID:17086203^[12]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000678)	Seeded From UniProt	complete
part_of	GO:0030424	axon	PMID:16701205^[13]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0030424	axon	PMID:15964824^[14]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0030424	axon	PMID:12950086^[15]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0030246	carbohydrate binding	PMID:19458237^[11]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0022010	central nervous system myelination	PMID:18650339^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2181052	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0021853	cerebral cortex GABAergic interneuron migration	PMID:11714688^[16]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(EMAPA:17544) results_in_movement_of:(CL:0000617)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010954	positive regulation of protein processing	PMID:18278038^[8]	ECO:0000314	direct assay evidence used in manual assertion		P	regulates_o_occurs_in:(CL:0000057) has_regulation_target:(MGI:MGI:88059)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0010769	regulation of cell morphogenesis involved in differentiation	PMID:18650339^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2181052	P	regulates_o_occurs_in:(EMAPA:17846) regulates_o_results_in_morphogenesis_of:(CL:0000127)	Seeded From UniProt	complete
part_of	GO:0009986	cell surface	PMID:8089271^[10]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(EMAPA:16525) part_of:(CL:0000100)\|part_of:(EMAPA:16525) part_of:(CL:0000100)\|part_of:(EMAPA:17577) part_of:(CL:0000100)\|part_of:(EMAPA:16659) part_of:(CL:0000117)\|part_of:(EMAPA:16659) part_of:(CL:0000117)\|part_of:(EMAPA:17264) part_of:(CL:0000117)\|part_of:(EMAPA:17264) part_of:(CL:0000117)\|part_of:(EMAPA:17576) part_of:(CL:0000117)\|part_of:(EMAPA:17576) part_of:(CL:0000117)\|part_of:(EMAPA:17576) part_of:(CL:0000117)\|part_of:(EMAPA:17576) part_of:(CL:0000117)\|part_of:(EMAPA:17576) part_of:(CL:0000117)\|part_of:(EMAPA:16478) part_of:(CL:0000117)\|part_of:(EMAPA:17074) part_of:(CL:0000117)\|part_of:(EMAPA:17074) part_of:(CL:0000117)\|part_of:(EMAPA:17787) part_of:(CL:0000117)\|part_of:(EMAPA:17787) part_of:(CL:0000117)\|part_of:(EMAPA:17787) part_of:(CL:0000117)\|part_of:(EMAPA:17787) part_of:(CL:0000117)\|part_of:(EMAPA:17787) part_of:(CL:0000117)\|part_of:(EMAPA:17078) part_of:(CL:0000117)\|part_of:(EMAPA:17078) part_of:(CL:0000117)\|part_of:(EMAPA:17544) part_of:(CL:0000117)\|part_of:(EMAPA:17544) part_of:(CL:0000117)\|part_of:(EMAPA:17544) part_of:(CL:0000117)\|part_of:(EMAPA:17797) part_of:(CL:0000117)\|part_of:(EMAPA:17550) part_of:(CL:0000117)\|part_of:(EMAPA:18591) part_of:(CL:0000117)\|part_of:(EMAPA:17846) part_of:(CL:0000117)\|part_of:(EMAPA:17797) part_of:(CL:0000117)\|part_of:(EMAPA:17545) part_of:(CL:0000117)\|part_of:(EMAPA:17550) part_of:(CL:0000117)\|part_of:(EMAPA:18591) part_of:(CL:0000117)\|part_of:(EMAPA:17846) part_of:(CL:0000117)\|part_of:(EMAPA:16910) part_of:(CL:0000117)\|part_of:(EMAPA:16910) part_of:(CL:0000117)\|part_of:(EMAPA:32870) part_of:(CL:0000117)\|part_of:(EMAPA:32869) part_of:(CL:0000117)\|part_of:(EMAPA:35547) part_of:(CL:0000117)\|part_of:(EMAPA:35437) part_of:(CL:0000117)\|part_of:(EMAPA:32845) part_of:(CL:0000117)\|part_of:(EMAPA:17575) part_of:(CL:0000117)\|part_of:(EMAPA:16668) part_of:(CL:0000540)\|part_of:(EMAPA:16668) part_of:(CL:0000540)\|part_of:(EMAPA:16668) part_of:(CL:0000540)\|part_of:(EMAPA:16668) part_of:(CL:0000540)\|part_of:(EMAPA:16668) part_of:(CL:0000540)\|part_of:(EMAPA:16668) part_of:(CL:0000540)\|part_of:(EMAPA:16668) part_of:(CL:0000540)\|part_of:(EMAPA:16668) part_of:(CL:0000540)\|part_of:(EMAPA:16989) part_of:(CL:0000540)\|part_of:(EMAPA:16989) part_of:(CL:0000540)\|part_of:(EMAPA:16989) part_of:(CL:0000540)\|part_of:(EMAPA:17577) part_of:(CL:0000540)\|part_of:(EMAPA:25149) part_of:(CL:0000540)\|part_of:(EMAPA:36513) part_of:(CL:0000540)\|part_of:(EMAPA:16800) part_of:(CL:0000540)\|part_of:(EMAPA:17606) part_of:(CL:0000540)\|part_of:(EMAPA:17168) part_of:(CL:0000540)	Seeded From UniProt	complete
part_of	GO:0009986	cell surface	PMID:17086203^[12]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000678)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007628	adult walking behavior	PMID:18760366^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2181052	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007612	learning	PMID:18760366^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2181052	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007413	axonal fasciculation	PMID:18650339^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2181052	P	occurs_in:(EMAPA:17168) occurs_in:(CL:0000740)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007411	axon guidance	PMID:18550718^[9]	ECO:0000316	genetic interaction evidence used in manual assertion	MGI:MGI:107558 MGI:MGI:96721	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007411	axon guidance	PMID:18550718^[9]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2677610	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007409	axonogenesis	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3821	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0007160	cell-matrix adhesion	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3821	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	RGD:3821	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001764	neuron migration	PMID:16225856^[17]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2181052	P		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0001764	neuron migration	PMID:11807022^[18]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	occurs_in:(EMAPA:16916) results_in_movement_of:(CL:0000117)	Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0000226	microtubule cytoskeleton organization	PMID:18650339^[7]	ECO:0000315	mutant phenotype evidence used in manual assertion	MGI:MGI:2181052	P	occurs_in:(EMAPA:17846) occurs_in:(CL:0000540)\|occurs_in:(EMAPA:17575) occurs_in:(CL:0000540)	Seeded From UniProt	complete
part_of	GO:0099025	anchored component of postsynaptic membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q02246 ensembl:ENSP00000330633	C		Seeded From UniProt	complete
involved_in	GO:0097090	presynaptic membrane organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q02246 ensembl:ENSP00000330633	P		Seeded From UniProt	complete
involved_in	GO:0007399	nervous system development	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR032991	P		Seeded From UniProt	complete
involved_in	GO:0031175	neuron projection development	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR032991	P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
involved_in	GO:0007155	cell adhesion	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0130	P		Seeded From UniProt	complete
part_of	GO:0031225	anchored component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0336	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 Savvaki, M et al. (2010) The expression of TAG-1 in glial cells is sufficient for the formation of the juxtaparanodal complex and the phenotypic rescue of tag-1 homozygous mutants in the CNS. J. Neurosci. 30 13943-54 PubMed GONUTS page
↑ ^2.0 ^2.1 Traka, M et al. (2003) Association of TAG-1 with Caspr2 is essential for the molecular organization of juxtaparanodal regions of myelinated fibers. J. Cell Biol. 162 1161-72 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 Poliak, S et al. (2003) Juxtaparanodal clustering of Shaker-like K+ channels in myelinated axons depends on Caspr2 and TAG-1. J. Cell Biol. 162 1149-60 PubMed GONUTS page
↑ Horresh, I et al. (2008) Multiple molecular interactions determine the clustering of Caspr2 and Kv1 channels in myelinated axons. J. Neurosci. 28 14213-22 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 Savvaki, M et al. (2008) Impairment of learning and memory in TAG-1 deficient mice associated with shorter CNS internodes and disrupted juxtaparanodes. Mol. Cell. Neurosci. 39 478-90 PubMed GONUTS page
↑ ^6.0 ^6.1 Fukamauchi, F et al. (2001) TAG-1-deficient mice have marked elevation of adenosine A1 receptors in the hippocampus. Biochem. Biophys. Res. Commun. 281 220-6 PubMed GONUTS page
↑ ^7.0 ^7.1 ^7.2 ^7.3 ^7.4 ^7.5 ^7.6 ^7.7 Chatzopoulou, E et al. (2008) Structural requirement of TAG-1 for retinal ganglion cell axons and myelin in the mouse optic nerve. J. Neurosci. 28 7624-36 PubMed GONUTS page
↑ ^8.0 ^8.1 Ma, QH et al. (2008) A TAG1-APP signalling pathway through Fe65 negatively modulates neurogenesis. Nat. Cell Biol. 10 283-94 PubMed GONUTS page
↑ ^9.0 ^9.1 ^9.2 ^9.3 Law, CO et al. (2008) The neural adhesion molecule TAG-1 modulates responses of sensory axons to diffusible guidance signals. Development 135 2361-71 PubMed GONUTS page
↑ ^10.0 ^10.1 ^10.2 Wolfer, DP et al. (1994) Distribution of TAG-1/axonin-1 in fibre tracts and migratory streams of the developing mouse nervous system. J. Comp. Neurol. 345 1-32 PubMed GONUTS page
↑ ^11.0 ^11.1 Lieberoth, A et al. (2009) Lewis(x) and alpha2,3-sialyl glycans and their receptors TAG-1, Contactin, and L1 mediate CD24-dependent neurite outgrowth. J. Neurosci. 29 6677-90 PubMed GONUTS page
↑ ^12.0 ^12.1 Okada, A et al. (2006) Boc is a receptor for sonic hedgehog in the guidance of commissural axons. Nature 444 369-73 PubMed GONUTS page
↑ Williams, SE et al. (2006) A role for Nr-CAM in the patterning of binocular visual pathways. Neuron 50 535-47 PubMed GONUTS page
↑ Laub, F et al. (2005) Transcription factor KLF7 is important for neuronal morphogenesis in selected regions of the nervous system. Mol. Cell. Biol. 25 5699-711 PubMed GONUTS page
↑ Zhong, JL et al. (2003) Pak1 and its T212 phosphorylated form accumulate in neurones and epithelial cells of the developing rodent. Dev. Dyn. 228 121-7 PubMed GONUTS page
↑ Denaxa, M et al. (2001) The adhesion molecule TAG-1 mediates the migration of cortical interneurons from the ganglionic eminence along the corticofugal fiber system. Development 128 4635-44 PubMed GONUTS page
↑ Denaxa, M et al. (2005) The adhesion molecule TAG-1 is required for proper migration of the superficial migratory stream in the medulla but not of cortical interneurons. Dev. Biol. 288 87-99 PubMed GONUTS page
↑ Kyriakopoulou, K et al. (2002) A combination of chain and neurophilic migration involving the adhesion molecule TAG-1 in the caudal medulla. Development 129 287-96 PubMed GONUTS page

[PMID:20962216-1] 1.0 ^1.1 Savvaki, M et al. (2010) The expression of TAG-1 in glial cells is sufficient for the formation of the juxtaparanodal complex and the phenotypic rescue of tag-1 homozygous mutants in the CNS. J. Neurosci. 30 13943-54 PubMed GONUTS page

[PMID:12975355-2] 2.0 ^2.1 Traka, M et al. (2003) Association of TAG-1 with Caspr2 is essential for the molecular organization of juxtaparanodal regions of myelinated fibers. J. Cell Biol. 162 1161-72 PubMed GONUTS page

[PMID:12963709-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 Poliak, S et al. (2003) Juxtaparanodal clustering of Shaker-like K+ channels in myelinated axons depends on Caspr2 and TAG-1. J. Cell Biol. 162 1149-60 PubMed GONUTS page

[PMID:19109503-4] Horresh, I et al. (2008) Multiple molecular interactions determine the clustering of Caspr2 and Kv1 channels in myelinated axons. J. Neurosci. 28 14213-22 PubMed GONUTS page

[PMID:18760366-5] 5.0 ^5.1 ^5.2 Savvaki, M et al. (2008) Impairment of learning and memory in TAG-1 deficient mice associated with shorter CNS internodes and disrupted juxtaparanodes. Mol. Cell. Neurosci. 39 478-90 PubMed GONUTS page

[PMID:11178983-6] 6.0 ^6.1 Fukamauchi, F et al. (2001) TAG-1-deficient mice have marked elevation of adenosine A1 receptors in the hippocampus. Biochem. Biophys. Res. Commun. 281 220-6 PubMed GONUTS page

[PMID:18650339-7] 7.0 ^7.1 ^7.2 ^7.3 ^7.4 ^7.5 ^7.6 ^7.7 Chatzopoulou, E et al. (2008) Structural requirement of TAG-1 for retinal ganglion cell axons and myelin in the mouse optic nerve. J. Neurosci. 28 7624-36 PubMed GONUTS page

[PMID:18278038-8] 8.0 ^8.1 Ma, QH et al. (2008) A TAG1-APP signalling pathway through Fe65 negatively modulates neurogenesis. Nat. Cell Biol. 10 283-94 PubMed GONUTS page

[PMID:18550718-9] 9.0 ^9.1 ^9.2 ^9.3 Law, CO et al. (2008) The neural adhesion molecule TAG-1 modulates responses of sensory axons to diffusible guidance signals. Development 135 2361-71 PubMed GONUTS page

[PMID:8089271-10] 10.0 ^10.1 ^10.2 Wolfer, DP et al. (1994) Distribution of TAG-1/axonin-1 in fibre tracts and migratory streams of the developing mouse nervous system. J. Comp. Neurol. 345 1-32 PubMed GONUTS page

[PMID:19458237-11] 11.0 ^11.1 Lieberoth, A et al. (2009) Lewis(x) and alpha2,3-sialyl glycans and their receptors TAG-1, Contactin, and L1 mediate CD24-dependent neurite outgrowth. J. Neurosci. 29 6677-90 PubMed GONUTS page

[PMID:17086203-12] 12.0 ^12.1 Okada, A et al. (2006) Boc is a receptor for sonic hedgehog in the guidance of commissural axons. Nature 444 369-73 PubMed GONUTS page

[PMID:16701205-13] Williams, SE et al. (2006) A role for Nr-CAM in the patterning of binocular visual pathways. Neuron 50 535-47 PubMed GONUTS page

[PMID:15964824-14] Laub, F et al. (2005) Transcription factor KLF7 is important for neuronal morphogenesis in selected regions of the nervous system. Mol. Cell. Biol. 25 5699-711 PubMed GONUTS page

[PMID:12950086-15] Zhong, JL et al. (2003) Pak1 and its T212 phosphorylated form accumulate in neurones and epithelial cells of the developing rodent. Dev. Dyn. 228 121-7 PubMed GONUTS page

[PMID:11714688-16] Denaxa, M et al. (2001) The adhesion molecule TAG-1 mediates the migration of cortical interneurons from the ganglionic eminence along the corticofugal fiber system. Development 128 4635-44 PubMed GONUTS page

[PMID:16225856-17] Denaxa, M et al. (2005) The adhesion molecule TAG-1 is required for proper migration of the superficial migratory stream in the medulla but not of cortical interneurons. Dev. Biol. 288 87-99 PubMed GONUTS page

[PMID:11807022-18] Kyriakopoulou, K et al. (2002) A combination of chain and neurophilic migration involving the adhesion molecule TAG-1 in the caudal medulla. Development 129 287-96 PubMed GONUTS page

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