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MOUSE:CNOT4

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Cnot4 (synonyms: Not4)
Protein Name(s) CCR4-NOT transcription complex subunit 4

CCR4-associated factor 4 E3 ubiquitin-protein ligase CNOT4 Potential transcriptional repressor NOT4Hp

External Links
UniProt Q8BT14
EMBL U71269
AK009234
AK028190
AK032248
BC058778
CCDS CCDS19999.1
RefSeq NP_001157883.1
NP_001157885.1
NP_058573.3
XP_006506442.1
UniGene Mm.214525
Mm.398182
PDB 2CPI
PDBsum 2CPI
ProteinModelPortal Q8BT14
SMR Q8BT14
PhosphoSite Q8BT14
MaxQB Q8BT14
PaxDb Q8BT14
PRIDE Q8BT14
Ensembl ENSMUST00000044163
ENSMUST00000114993
GeneID 53621
KEGG mmu:53621
UCSC uc009bid.2
uc009big.2
CTD 4850
MGI MGI:1859026
eggNOG COG5175
GeneTree ENSGT00390000000068
HOGENOM HOG000065696
HOVERGEN HBG051043
InParanoid Q8BT14
KO K10643
OrthoDB EOG790G0K
PhylomeDB Q8BT14
TreeFam TF106134
Reactome REACT_244119
UniPathway UPA00143
EvolutionaryTrace Q8BT14
NextBio 310353
PRO PR:Q8BT14
Proteomes UP000000589
Bgee Q8BT14
CleanEx MM_CNOT4
ExpressionAtlas Q8BT14
Genevestigator Q8BT14
GO GO:0030014
GO:0005737
GO:0005634
GO:0016874
GO:0000166
GO:0044822
GO:0004842
GO:0008270
GO:0051865
GO:0006355
GO:0006351
Gene3D 3.30.40.10
3.30.70.330
InterPro IPR012677
IPR000504
IPR000571
IPR001841
IPR013083
SMART SM00184
SM00360
PROSITE PS50102
PS50103
PS50089

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0045652

regulation of megakaryocyte differentiation

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O95628

P

Seeded From UniProt

complete

involved_in

GO:0006511

ubiquitin-dependent protein catabolic process

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O95628

P

Seeded From UniProt

complete

involved_in

GO:0051865

protein autoubiquitination

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O95628

P

Seeded From UniProt

complete

colocalizes_with

GO:0030014

CCR4-NOT complex

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O95628

C

Seeded From UniProt

complete

enables

GO:0004842

ubiquitin-protein transferase activity

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:O95628

F

Seeded From UniProt

complete

part_of

GO:0030014

CCR4-NOT complex

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000288208
PomBase:SPAC16C9.04c
UniProtKB:O95628

C

Seeded From UniProt

complete

involved_in

GO:0016567

protein ubiquitination

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000288208
SGD:S000000870

P

Seeded From UniProt

complete

enables

GO:0004842

ubiquitin-protein transferase activity

PMID:21873635[1]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

PANTHER:PTN000288208
SGD:S000000870
UniProtKB:O95628

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0051865

protein autoubiquitination

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:O95628

P

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0045652

regulation of megakaryocyte differentiation

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:O95628

P

Seeded From UniProt

complete

colocalizes_with

GO:0030014

CCR4-NOT complex

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:O95628

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0006511

ubiquitin-dependent protein catabolic process

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:O95628

P

Seeded From UniProt

complete

enables

GO:0004842

ubiquitin-protein transferase activity

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:O95628

F

Seeded From UniProt

complete

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000504
InterPro:IPR003954
InterPro:IPR035979

F

Seeded From UniProt

complete

enables

GO:0004842

ubiquitin-protein transferase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039780

F

Seeded From UniProt

complete

part_of

GO:0030014

CCR4-NOT complex

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR039780

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000571

F

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0694

F

Seeded From UniProt

complete

enables

GO:0016740

transferase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0808

F

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

enables

GO:0046872

metal ion binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0479

F

Seeded From UniProt

complete

involved_in

GO:0016567

protein ubiquitination

GO_REF:0000041

ECO:0000322

imported manually asserted information used in automatic assertion

UniPathway:UPA00143

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 1.2 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page