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MOUSE:ARHG6
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Arhgef6 | |
| Protein Name(s) | Rho guanine nucleotide exchange factor 6
Alpha-PIX Rac/Cdc42 guanine nucleotide exchange factor 6 | |
| External Links | ||
| UniProt | Q8K4I3 | |
| EMBL | AF393831 AK040468 | |
| RefSeq | NP_690014.2 | |
| UniGene | Mm.261443 | |
| PDB | 1V61 | |
| PDBsum | 1V61 | |
| ProteinModelPortal | Q8K4I3 | |
| SMR | Q8K4I3 | |
| BioGrid | 215941 | |
| IntAct | Q8K4I3 | |
| MINT | MINT-4117855 | |
| PhosphoSite | Q8K4I3 | |
| MaxQB | Q8K4I3 | |
| PaxDb | Q8K4I3 | |
| PRIDE | Q8K4I3 | |
| DNASU | 73341 | |
| GeneID | 73341 | |
| KEGG | mmu:73341 | |
| UCSC | uc009thd.2 | |
| CTD | 9459 | |
| MGI | MGI:1920591 | |
| eggNOG | NOG314429 | |
| HOGENOM | HOG000231381 | |
| HOVERGEN | HBG050569 | |
| InParanoid | Q8K4I3 | |
| KO | K05729 | |
| PhylomeDB | Q8K4I3 | |
| Reactome | REACT_204733 REACT_209641 REACT_210090 REACT_255191 | |
| EvolutionaryTrace | Q8K4I3 | |
| NextBio | 338019 | |
| PRO | PR:Q8K4I3 | |
| Proteomes | UP000000589 | |
| Bgee | Q8K4I3 | |
| ExpressionAtlas | Q8K4I3 | |
| Genevestigator | Q8K4I3 | |
| GO | GO:0005911 GO:0030027 GO:0005089 GO:0035556 GO:0030032 | |
| Gene3D | 1.10.418.10 1.20.900.10 2.30.29.30 | |
| InterPro | IPR001715 IPR000219 IPR001331 IPR001849 IPR011993 IPR001452 IPR003096 | |
| Pfam | PF00307 PF00169 PF00621 PF14604 | |
| PRINTS | PR00452 PR00888 | |
| SMART | SM00033 SM00233 SM00325 SM00326 | |
| SUPFAM | SSF47576 SSF48065 SSF50044 | |
| PROSITE | PS50021 PS00741 PS50010 PS50003 PS50002 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0030032 |
lamellipodium assembly |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030027 |
lamellipodium |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005911 |
cell-cell junction |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005085 |
guanyl-nucleotide exchange factor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005089 |
Rho guanyl-nucleotide exchange factor activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0035023 |
regulation of Rho protein signal transduction |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0035556 |
intracellular signal transduction |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0042995 |
cell projection |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0005085 |
guanyl-nucleotide exchange factor activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030027 |
lamellipodium |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Matsuda, C et al. (2008) Affixin activates Rac1 via betaPIX in C2C12 myoblast. FEBS Lett. 582 1189-96 PubMed GONUTS page
- ↑ Liang, Y et al. (2013) The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells. Nat. Immunol. 14 858-66 PubMed GONUTS page
