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MOUSE:APCD1

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Species (Taxon ID) Mus musculus (Mouse). (10090)
Gene Name(s) Apcdd1 (ECO:0000312 with MGI:MGI:3513977) (synonyms: Drapc1 (ECO:0000303 with PMID:15465500[1]))
Protein Name(s) Protein APCDD1

Adenomatosis polyposis coli down-regulated 1 protein homolog

External Links
UniProt Q3U128
EMBL AK156319
AK172004
BC141269
BC141270
CCDS CCDS37843.1
RefSeq NP_573500.2
UniGene Mm.391102
STRING 10090.ENSMUSP00000094302
PhosphoSite Q3U128
MaxQB Q3U128
PRIDE Q3U128
Ensembl ENSMUST00000096554
ENSMUST00000163716
GeneID 494504
KEGG mmu:494504
UCSC uc008fdl.1
CTD 147495
MGI MGI:3513977
eggNOG NOG42984
GeneTree ENSGT00640000091492
HOGENOM HOG000033991
HOVERGEN HBG060356
InParanoid Q3U128
OMA AIEGHWV
OrthoDB EOG7PK8Z4
PhylomeDB Q3U128
TreeFam TF329491
ChiTaRS Apcdd1
NextBio 411763
PRO PR:Q3U128
Proteomes UP000000589
Bgee Q3U128
CleanEx MM_APCDD1
Genevisible Q3U128
GO GO:0005887
GO:0017147
GO:0043615
GO:0001942
GO:0030178
GO:0016055
InterPro IPR029405
Pfam PF14921

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0042487

regulation of odontogenesis of dentin-containing tooth

PMID:26170146[2]

ECO:0000315

P

Figure 5 shows the effect of knockdown of apcdd1 on tooth development. The AS-ODN-treated teeth (knockdown) showed irregular morphology of the crown and cusp.

complete
CACAO 10988

involved_in

GO:0030178

negative regulation of Wnt signaling pathway

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q8J025

P

Seeded From UniProt

complete

enables

GO:0017147

Wnt-protein binding

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q8J025

F

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

GO_REF:0000024

ECO:0000250

sequence similarity evidence used in manual assertion

UniProtKB:Q8J025

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0043615

astrocyte cell migration

PMID:22500632[3]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q8J025

F

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0030178

negative regulation of Wnt signaling pathway

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q8J025

P

Seeded From UniProt

complete

enables

GO:0017147

Wnt-protein binding

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q8J025

F

Seeded From UniProt

complete

part_of

GO:0005887

integral component of plasma membrane

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q8J025

C

Seeded From UniProt

complete

acts_upstream_of_or_within

GO:0001942

hair follicle development

GO_REF:0000096

ECO:0000266

sequence orthology evidence used in manual assertion

UniProtKB:Q8J025

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1003
UniProtKB-SubCell:SL-0039

C

Seeded From UniProt

complete

involved_in

GO:0016055

Wnt signaling pathway

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0879

P

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Jukkola, T et al. (2004) Drapc1 expression during mouse embryonic development. Gene Expr. Patterns 4 755-62 PubMed GONUTS page
  2. Neupane, S et al. (2015) The role of APCDD1 in epithelial rearrangement in tooth morphogenesis. Histochem. Cell Biol. 144 377-87 PubMed GONUTS page
  3. Kang, P et al. (2012) Sox9 and NFIA coordinate a transcriptional regulatory cascade during the initiation of gliogenesis. Neuron 74 79-94 PubMed GONUTS page