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MOUSE:ADRM1
Contents
| Species (Taxon ID) | Mus musculus (Mouse). (10090) | |
| Gene Name(s) | Adrm1 (synonyms: Gp110) | |
| Protein Name(s) | Proteasomal ubiquitin receptor ADRM1
110 kDa cell membrane glycoprotein Gp110 Adhesion-regulating molecule 1 ARM-1 Rpn13 homolog | |
| External Links | ||
| UniProt | Q9JKV1 | |
| EMBL | AF225959 AK075674 AK145474 AK145792 AK166878 AL663027 BC008974 BC031517 | |
| CCDS | CCDS17171.1 | |
| RefSeq | NP_062796.2 | |
| UniGene | Mm.379082 | |
| PDB | 2R2Y 2Z59 | |
| PDBsum | 2R2Y 2Z59 | |
| ProteinModelPortal | Q9JKV1 | |
| SMR | Q9JKV1 | |
| BioGrid | 207978 | |
| DIP | DIP-60625N | |
| IntAct | Q9JKV1 | |
| PhosphoSite | Q9JKV1 | |
| MaxQB | Q9JKV1 | |
| PaxDb | Q9JKV1 | |
| PRIDE | Q9JKV1 | |
| Ensembl | ENSMUST00000061437 | |
| GeneID | 56436 | |
| KEGG | mmu:56436 | |
| UCSC | uc008oin.1 | |
| CTD | 11047 | |
| MGI | MGI:1929289 | |
| eggNOG | NOG288027 | |
| GeneTree | ENSGT00390000013839 | |
| HOGENOM | HOG000005947 | |
| HOVERGEN | HBG073518 | |
| InParanoid | Q9JKV1 | |
| OMA | MQNNAKP | |
| OrthoDB | EOG70KGQZ | |
| PhylomeDB | Q9JKV1 | |
| TreeFam | TF313410 | |
| EvolutionaryTrace | Q9JKV1 | |
| NextBio | 312618 | |
| PRO | PR:Q9JKV1 | |
| Proteomes | UP000000589 | |
| Bgee | Q9JKV1 | |
| CleanEx | MM_ADRM1 | |
| Genevestigator | Q9JKV1 | |
| GO | GO:0005737 GO:0005634 GO:0000502 GO:0060612 GO:0042699 GO:0048477 GO:0001541 GO:0060399 GO:0033081 GO:0072520 GO:0060009 GO:0007286 GO:0048538 | |
| InterPro | IPR006773 | |
| PANTHER | PTHR12225 | |
| Pfam | PF04683 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0007283 |
spermatogenesis |
21048919 |
ECO:0000315 |
P |
Histological analysis of 12 weeks old Rpn13 -/- male mice revealed azoospermia (Figure 6). |
Missing: reference | ||||
| GO:0035239 |
tube morphogenesis |
21048919 |
ECO:0000315 |
P |
Histological analysis of 12 weeks old Rpn13-/- male mice revealed hypoplasia of seminiferous tubules(Figure 6). |
Missing: reference | ||||
| GO:0061039 |
ovum-producing ovary development |
21048919 |
ECO:0000315 |
P |
In contrast, in young female Rpn13-/- mice there were relatively few ova and those present were surrounded by a single layer of cells. |
Missing: reference | ||||
| GO:0070341 |
fat cell proliferation |
21048919 |
ECO:0000315 |
P |
Independent of body weight, gender, or age, all Rpn13-/- mice had significantly higher body fat content detected by NMR analysis(Figure 5B) |
Missing: reference | ||||
|
involved_in |
GO:0072520 |
seminiferous tubule development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0060612 |
adipose tissue development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0060399 |
positive regulation of growth hormone receptor signaling pathway |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0060009 |
Sertoli cell development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0048538 |
thymus development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0048477 |
oogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042699 |
follicle-stimulating hormone signaling pathway |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0033081 |
regulation of T cell differentiation in thymus |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0007286 |
spermatid development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0001541 |
ovarian follicle development |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
enables |
GO:0070628 |
proteasome binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000259827 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0061133 |
endopeptidase activator activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000259827 |
F |
Seeded From UniProt |
complete | ||
|
enables |
GO:0043130 |
ubiquitin binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000259827 |
F |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0008541 |
proteasome regulatory particle, lid subcomplex |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000259827 |
C |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006511 |
ubiquitin-dependent protein catabolic process |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000259827 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0070628 |
proteasome binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
enables |
GO:0061133 |
endopeptidase activator activity |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0043248 |
proteasome assembly |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
acts_upstream_of_or_within |
GO:0006368 |
transcription elongation from RNA polymerase II promoter |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005886 |
plasma membrane |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005829 |
cytosol |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005654 |
nucleoplasm |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0002020 |
protease binding |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000502 |
proteasome complex |
ECO:0000266 |
sequence orthology evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0010950 |
positive regulation of endopeptidase activity |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0061133 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0010950 |
positive regulation of endopeptidase activity |
ECO:0000364 |
evidence based on logical inference from manual annotation used in automatic assertion |
GO:0061133 |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005737 |
cytoplasm |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0000502 |
proteasome complex |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Al-Shami, A et al. (2010) Regulators of the proteasome pathway, Uch37 and Rpn13, play distinct roles in mouse development. PLoS ONE 5 e13654 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
g
o
p
- GO:0005886 ! plasma membrane
- GO:0010950 ! positive regulation of endopeptidase activity
- GO:0060399 ! positive regulation of growth hormone receptor signaling pathway
- GO:0002020 ! protease binding
- GO:0043248 ! proteasome assembly
- GO:0070628 ! proteasome binding
- GO:0000502 ! proteasome complex
- GO:0008541 ! proteasome regulatory particle, lid subcomplex
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