MOUSE:ACTS

Species (Taxon ID)	Mus musculus (Mouse). (10090)
Gene Name(s)	Acta1 (synonyms: Acta)
Protein Name(s)	Actin, alpha skeletal muscle Alpha-actin-1
External Links
UniProt	P68134
EMBL	M12866 M12347 BC014877
CCDS	CCDS22764.1
PIR	A24904
RefSeq	NP_001258970.1 NP_033736.1
UniGene	Mm.214950
PDB	4B1U
PDBsum	4B1U
ProteinModelPortal	P68134
SMR	P68134
BioGrid	197943
IntAct	P68134
MINT	MINT-149880
PhosphoSite	P68134
MaxQB	P68134
PRIDE	P68134
Ensembl	ENSMUST00000034453
GeneID	11459
KEGG	mmu:11459
UCSC	uc009nwr.1
CTD	58
MGI	MGI:87902
GeneTree	ENSGT00760000118957
HOGENOM	HOG000233340
HOVERGEN	HBG003771
InParanoid	P68134
KO	K10354
OMA	EDAKHYM
OrthoDB	EOG72RMZ1
PhylomeDB	P68134
TreeFam	TF354237
Reactome	REACT_232053
ChiTaRS	Acta1
NextBio	278780
PRO	PR:P68134
Proteomes	UP000000589
Bgee	P68134
CleanEx	MM_ACTA1
Genevestigator	P68134
GO	GO:0005884 GO:0072562 GO:0070062 GO:0043234 GO:0001725 GO:0005865 GO:0005524 GO:0016049 GO:0009991 GO:0010226 GO:0009612 GO:0048545 GO:0043503 GO:0048741 GO:0030240
InterPro	IPR004000 IPR020902 IPR004001
PANTHER	PTHR11937
Pfam	PF00022
PRINTS	PR00190
SMART	SM00268
PROSITE	PS00406 PS00432 PS01132

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0090131	mesenchyme migration	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P08023	P		Seeded From UniProt	complete
involved_in	GO:0010628	positive regulation of gene expression	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P08023	P	has_regulation_target:(UniProtKB:E1C3A6)	Seeded From UniProt	complete
part_of	GO:0044297	cell body	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P08023	C	part_of:(CL:0000134)	Seeded From UniProt	complete
part_of	GO:0030175	filopodium	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P08023	C	part_of:(CL:0000134)	Seeded From UniProt	complete
part_of	GO:0030027	lamellipodium	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P08023	C	part_of:(CL:0000134)	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P08023	C	part_of:(CL:0000134)	Seeded From UniProt	complete
involved_in	GO:0048741	skeletal muscle fiber development	PMID:2731651	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0030240	skeletal muscle thin filament assembly	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P68133	P		Seeded From UniProt	complete
part_of	GO:0005884	actin filament	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P68133	C		Seeded From UniProt	complete
part_of	GO:0001725	stress fiber	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P68133	C		Seeded From UniProt	complete
part_of	GO:0032991	protein-containing complex	PMID:18468998	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P62736	C		Seeded From UniProt	complete
acts_upstream_of_or_within	GO:0030240	skeletal muscle thin filament assembly	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P68133	P		Seeded From UniProt	complete
part_of	GO:0030017	sarcomere	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P68133	C		Seeded From UniProt	complete
part_of	GO:0015629	actin cytoskeleton	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P68133	C		Seeded From UniProt	complete
part_of	GO:0005884	actin filament	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P68133	C		Seeded From UniProt	complete
part_of	GO:0005865	striated muscle thin filament	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P68133	C		Seeded From UniProt	complete
part_of	GO:0001725	stress fiber	GO_REF:0000096	ECO:0000266	sequence orthology evidence used in manual assertion	UniProtKB:P68133	C		Seeded From UniProt	complete
involved_in	GO:0030240	skeletal muscle thin filament assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P68133 ensembl:ENSP00000355645	P		Seeded From UniProt	complete
part_of	GO:0030017	sarcomere	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P68133 ensembl:ENSP00000355645	C		Seeded From UniProt	complete
part_of	GO:0015629	actin cytoskeleton	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P68133 ensembl:ENSP00000355645	C		Seeded From UniProt	complete
part_of	GO:0005884	actin filament	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P68133 ensembl:ENSP00000355645	C		Seeded From UniProt	complete
part_of	GO:0005865	striated muscle thin filament	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P68133 ensembl:ENSP00000355645	C		Seeded From UniProt	complete
part_of	GO:0001725	stress fiber	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P68133 ensembl:ENSP00000355645	C		Seeded From UniProt	complete
involved_in	GO:0071417	cellular response to organonitrogen compound	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P68136 ensembl:ENSRNOP00000024084	P		Seeded From UniProt	complete
involved_in	GO:0048545	response to steroid hormone	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P68136 ensembl:ENSRNOP00000024084	P		Seeded From UniProt	complete
involved_in	GO:0043503	skeletal muscle fiber adaptation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P68136 ensembl:ENSRNOP00000024084	P		Seeded From UniProt	complete
involved_in	GO:0010226	response to lithium ion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P68136 ensembl:ENSRNOP00000024084	P		Seeded From UniProt	complete
involved_in	GO:0009991	response to extracellular stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P68136 ensembl:ENSRNOP00000024084	P		Seeded From UniProt	complete
involved_in	GO:0009612	response to mechanical stimulus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P68136 ensembl:ENSRNOP00000024084	P		Seeded From UniProt	complete
part_of	GO:0005865	striated muscle thin filament	PMID:2731651	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F		Seeded From UniProt	complete
part_of	GO:0005856	cytoskeleton	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0206 UniProtKB-SubCell:SL-0090	C		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0963	C		Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F		Seeded From UniProt	complete
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References

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