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LISMO:Q8Y6M8
Contents
| Species (Taxon ID) | Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e). (169963) | |
| Gene Name(s) | No Information Provided. | |
| Protein Name(s) | Lmo1656 protein (ECO:0000313 with EMBL:CAC99734.1) | |
| External Links | ||
| UniProt | Q8Y6M8 | |
| EMBL | AL591980 | |
| PIR | AH1281 | |
| RefSeq | NP_465181.1 WP_009932546.1 | |
| PaxDb | Q8Y6M8 | |
| EnsemblBacteria | CAC99734 | |
| GeneID | 985594 | |
| KEGG | lmo:lmo1656 | |
| PATRIC | fig|169963.11.peg.1699 | |
| HOGENOM | HOG000100882 | |
| OMA | ITMERRY | |
| BioCyc | LMON169963:G1GTA-1749-MONOMER | |
| Proteomes | UP000000817 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
| GO:0009405 |
pathogenesis |
ECO:0000315 |
mutant phenotype evidence used in manual assertion |
P |
The protein Lmo1656 is a virulence factor secreted by Listeria Monocytogenes. In figure 3 C -D orally innoculated mice infected with the mutant version delta lmo1656 were found to have lower bacterial burden 48 hours post infection. The proposed mechanism is through lm protein docking at E-CAD surface protein. They have also done the same test intravenously and it shows no decrease in virulence suggesting that this protein specifically helps the bacteria when infecting through the oral route. |
complete | ||||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ David, DJ et al. (2018) Lmo1656 is a secreted virulence factor of Listeria monocytogenes that interacts with the sortin nexin 6-BAR complex. J. Biol. Chem. PubMed GONUTS page
