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LISMO:PRFA

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Species (Taxon ID) Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e). (169963)
Gene Name(s) prfA
Protein Name(s) Listeriolysin regulatory protein
External Links
UniProt P22262
EMBL X61210
M55160
AJ002742
AL591974
PIR AI1099
S16890
RefSeq NP_463731.1
WP_003722729.1
YP_007602416.1
YP_008273512.1
YP_008274522.1
YP_008279488.1
YP_008281766.1
YP_008282691.1
YP_008298400.1
YP_008303431.1
YP_008305045.1
PDB 1OMI
2BEO
2BGC
PDBsum 1OMI
2BEO
2BGC
ProteinModelPortal P22262
SMR P22262
STRING 169963.lmo0200
EnsemblBacteria CAD00727
GeneID 14824603
16308916
16309966
16315092
16320614
16324568
16335585
16340760
16342549
987031
KEGG lmo:lmo0200
lmoe:BN418_0210
PATRIC 20309407
GenoList LMO0200
eggNOG COG0664
OMA DICHCEA
OrthoDB EOG6R87DH
PhylomeDB P22262
BioCyc LMON169963:LMO0200-MONOMER
EvolutionaryTrace P22262
Proteomes UP000000817
GO GO:0005622
GO:0003677
GO:0003700
GO:0009405
GO:0006351
Gene3D 1.10.10.10
2.60.120.10
InterPro IPR018490
IPR012318
IPR014710
IPR018335
IPR011991
SUPFAM SSF51206
PROSITE PS00042
PS51063

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0009405

pathogenesis

PMID:1729245[1]

ECO:0000315

P

Figure 6. shows that prfA mutant strains EGD prfAI and SLCC 53 prfA were less virulent and exhibited reduced growth in host tissue.

complete
CACAO 5997

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012318

F

Seeded From UniProt

complete

enables

GO:0003700

DNA-binding transcription factor activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR018335

F

Seeded From UniProt

complete

involved_in

GO:0006355

regulation of transcription, DNA-templated

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR012318
InterPro:IPR018335

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

involved_in

GO:0009405

pathogenesis

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0843

P

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Chakraborty, T et al. (1992) Coordinate regulation of virulence genes in Listeria monocytogenes requires the product of the prfA gene. J. Bacteriol. 174 568-74 PubMed GONUTS page