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LEPIN:Q8EXZ9

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Species (Taxon ID) Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai(strain 56601). (189518)
Gene Name(s) htpG (ECO:0000313 with EMBL:AAN51617.1)
Protein Name(s) Heat shock protein 90 (ECO:0000313 with EMBL:AAN51617.1)
External Links
UniProt Q8EXZ9
EMBL AE010301
RefSeq NP_714602.1
ProteinModelPortal Q8EXZ9
STRING 189518.LB058
EnsemblBacteria AAN51617
GeneID 1153984
KEGG lil:LB_058
PATRIC 22389669
HOGENOM HOG000031986
InParanoid Q8EXZ9
KO K04079
OMA MITQSEY
OrthoDB EOG65TRNM
BioCyc LINT189518:GJBB-3502-MONOMER
Proteomes UP000001408
GO GO:0005524
GO:0006457
GO:0006950
Gene3D 3.30.565.10
InterPro IPR003594
IPR001404
IPR020575
IPR020568
PANTHER PTHR11528
Pfam PF00183
PIRSF PIRSF002583
PRINTS PR00775
SMART SM00387
SUPFAM SSF54211
SSF55874

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0009405

pathogenesis

PMID:24366253[1]

ECO:0000315

P

Table 2 shows that all hamsters treated with the htpG- strain of L.interrogans survived at all doses. All hamsters infected with the wild-type strain and the complemented strain died.

complete
CACAO 10424

involved_in

GO:0009405

pathogenesis

PMID:24366253[1]

ECO:0000315

mutant phenotype evidence used in manual assertion

P

Seeded From UniProt

complete

enables

GO:0042802

identical protein binding

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10461
PANTHER:PTN000163828

F

Seeded From UniProt

complete

enables

GO:0042623

ATPase activity, coupled

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10461
PANTHER:PTN000163828

F

Seeded From UniProt

complete

involved_in

GO:0009408

response to heat

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10461
PANTHER:PTN000163828

P

Seeded From UniProt

complete

involved_in

GO:0006974

cellular response to DNA damage stimulus

PMID:21873635[2]

ECO:0000318

biological aspect of ancestor evidence used in manual assertion

EcoGene:EG10461
PANTHER:PTN000163828

P

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001404

F

Seeded From UniProt

complete

involved_in

GO:0006457

protein folding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001404

P

Seeded From UniProt

complete

enables

GO:0051082

unfolded protein binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001404

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 King, AM et al. (2014) High-temperature protein G is an essential virulence factor of Leptospira interrogans. Infect. Immun. 82 1123-31 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page