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LACF3:ADDA

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Species (Taxon ID) Lactobacillus fermentum (strain NBRC 3956 / LMG 18251). (334390)
Gene Name(s) addA (ECO:0000255 with HAMAP-Rule:MF_01451)
Protein Name(s) ATP-dependent helicase/nuclease subunit A (ECO:0000255 with HAMAP-Rule:MF_01451)

ATP-dependent helicase/nuclease AddA (ECO:0000255 with HAMAP-Rule:MF_01451)

External Links
UniProt B2GEY4
EMBL AP008937
RefSeq YP_001842853.1
STRING 334390.LAF_0037
EnsemblBacteria BAG26373
GeneID 6233610
KEGG lfe:LAF_0037
PATRIC 22224008
eggNOG COG1074
HOGENOM HOG000015621
KO K16898
OMA TADIGTM
OrthoDB EOG6HJ22G
BioCyc LFER334390:GJ2S-38-MONOMER
Proteomes UP000001697
GO GO:0008408
GO:0005524
GO:0004003
GO:0003690
GO:0000724
Gene3D 3.40.50.300
3.90.320.10
HAMAP MF_01451
InterPro IPR014152
IPR014017
IPR000212
IPR011604
IPR027417
IPR011335
IPR014016
PANTHER PTHR11070
Pfam PF00580
PF13361
SUPFAM SSF52540
SSF52980
TIGRFAMs TIGR02785
PROSITE PS51198
PS51217

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0006302

double-strand break repair

PMID:21071401[1]

ECO:0000314

P

Figure 5. A single helicase motor catalyses processive DNA unwinding by AddAB.

complete

involved_in

GO:0032508

DNA duplex unwinding

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004003

P

Seeded From UniProt

complete

involved_in

GO:0032508

DNA duplex unwinding

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004003

P

Seeded From UniProt

complete

involved_in

GO:0090305

nucleic acid phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0008408

P

Seeded From UniProt

complete

involved_in

GO:0090305

nucleic acid phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004527

P

Seeded From UniProt

complete

involved_in

GO:0090305

nucleic acid phosphodiester bond hydrolysis

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0004518

P

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000212

F

Seeded From UniProt

complete

enables

GO:0004003

ATP-dependent DNA helicase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000212
InterPro:IPR014152

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR000212
InterPro:IPR014016
InterPro:IPR014017
InterPro:IPR034739

F

Seeded From UniProt

complete

involved_in

GO:0006302

double-strand break repair

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014152

P

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR014017

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000053577

F

Seeded From UniProt

complete

enables

GO:0004003

ATP-dependent DNA helicase activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000053577

F

Seeded From UniProt

complete

enables

GO:0003690

double-stranded DNA binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000053577

F

Seeded From UniProt

complete

involved_in

GO:0000724

double-strand break repair via homologous recombination

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000053577

P

Seeded From UniProt

complete

enables

GO:0008408

3'-5' exonuclease activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000053577

F

Seeded From UniProt

complete

enables

GO:0005524

ATP binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0067

F

Seeded From UniProt

complete

enables

GO:0003677

DNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0238

F

Seeded From UniProt

complete

enables

GO:0016787

hydrolase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0378

F

Seeded From UniProt

complete

enables

GO:0004527

exonuclease activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0269

F

Seeded From UniProt

complete

enables

GO:0000166

nucleotide binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0547

F

Seeded From UniProt

complete

involved_in

GO:0006974

cellular response to DNA damage stimulus

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0227

P

Seeded From UniProt

complete

enables

GO:0004518

nuclease activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0540

F

Seeded From UniProt

complete

involved_in

GO:0006281

DNA repair

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0234

P

Seeded From UniProt

complete

enables

GO:0004386

helicase activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0347

F

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Yeeles, JT et al. (2011) The AddAB helicase-nuclease catalyses rapid and processive DNA unwinding using a single Superfamily 1A motor domain. Nucleic Acids Res. 39 2271-85 PubMed GONUTS page