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I33A0:M1

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Species (Taxon ID) Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus(strain A/WS/1933 H1N1)). (381518)
Gene Name(s) M
Protein Name(s) Matrix protein 1

M1

External Links
UniProt P05777
EMBL X08088
M23920
M19374
L25818
PIR A28608
S07429
PDB 4PUS
PDBsum 4PUS
ProteinModelPortal P05777
SMR P05777
Proteomes UP000000834
GO GO:0042025
GO:0055036
GO:0003723
GO:0039660
GO:0039573
Gene3D 1.10.10.180
1.20.91.10
InterPro IPR013188
IPR001561
IPR015423
IPR015799
Pfam PF00598
PF08289
ProDom PD596253
PD001061
SMART SM00759
SUPFAM SSF48145

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status
GO:0071426

ribonucleoprotein complex export from nucleus

PMID:10644350[1]

ECO:0005804

immunofluorescence evidence used in manual assertion

P

Fig. 4 shows that infected CHO cells stably expressing M1 are able to export NP to the cytoplasm while infected CHO cells not expressing M1 cannot.

Organism: Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain A/WS/1933 H1N1)) UniProtKB: P05777 (M1_I33A0) UniProt submitted name: Matrix protein 1

complete

GO:0042025

host cell nucleus

PMID:10644350[1]

ECO:0005804

immunofluorescence evidence used in manual assertion

C

Fig. 4 Shows M1 is required for NP export from the host nucleus.

Organism: Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain A/WS/1933 H1N1)) UniProtKB:P05777 (M1_I33A0) UniProt submitted name: Matrix protein 1

complete
CACAO 13826

GO:0031224

intrinsic component of membrane

PMID:10954572[2]

ECO:0007104

co-fractionation evidence used in manual assertion

C

Fig. 1 shows presence of M1 in cell membrane fraction as analyzed by SDS-PAGE.

Organism: Influenza A virus (strain A/Wilson-Smith/1933 H1N1) (Influenza A virus (strain A/WS/1933 H1N1)) UniProtKB: P05777 (M1_I33A0) UniProt submitted name: Matrix protein 1

complete
CACAO 13832

enables

GO:0003723

RNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001561
InterPro:IPR013188
InterPro:IPR015799
InterPro:IPR036039

F

Seeded From UniProt

complete

enables

GO:0005198

structural molecule activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR001561
InterPro:IPR013188
InterPro:IPR015799
InterPro:IPR036039

F

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000568465

F

Seeded From UniProt

complete

enables

GO:0039660

structural constituent of virion

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000568465

F

Seeded From UniProt

complete

part_of

GO:0055036

virion membrane

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000568465

C

Seeded From UniProt

complete

part_of

GO:0042025

host cell nucleus

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000568465

C

Seeded From UniProt

complete

involved_in

GO:0046761

viral budding from plasma membrane

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000568465

P

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0694

F

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

enables

GO:0039660

structural constituent of virion

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0468

F

Seeded From UniProt

complete

part_of

GO:0019012

virion

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0946

C

Seeded From UniProt

complete

part_of

GO:0042025

host cell nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1048
UniProtKB-SubCell:SL-0414

C

Seeded From UniProt

complete

part_of

GO:0055036

virion membrane

GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-SubCell:SL-0275

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Bui, M et al. (2000) Role of the influenza virus M1 protein in nuclear export of viral ribonucleoproteins. J. Virol. 74 1781-6 PubMed GONUTS page
  2. Ali, A et al. (2000) Influenza virus assembly: effect of influenza virus glycoproteins on the membrane association of M1 protein. J. Virol. 74 8709-19 PubMed GONUTS page