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HV1BR:VPU

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Species (Taxon ID) Human immunodeficiency virus type 1 group M subtype B (isolateBRU/LAI) (HIV-1). (11686)
Gene Name(s) vpu
Protein Name(s) Protein Vpu

U ORF protein Viral protein U

External Links
UniProt P05923
EMBL K02013
M19921
ProteinModelPortal P05923
SMR P05923
IntAct P05923
MINT MINT-8402293
Proteomes UP000007692
GO GO:0033644
GO:0016021
GO:0005261
GO:0006915
GO:0032801
GO:0039587
GO:0039502
GO:0019076
Gene3D 1.10.195.10
InterPro IPR008187
IPR009032
Pfam PF00558
SUPFAM SSF57647

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

involved_in

GO:0019076

viral release from host cell

PMID:20529266[1]

ECO:0000314

direct assay evidence used in manual assertion

P

Seeded From UniProt

complete

involved_in

GO:0034220

ion transmembrane transport

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005261

P

Seeded From UniProt

complete

involved_in

GO:0034220

ion transmembrane transport

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005261

P

Seeded From UniProt

complete

involved_in

GO:0098655

cation transmembrane transport

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005261

P

Seeded From UniProt

complete

involved_in

GO:0098655

cation transmembrane transport

GO_REF:0000108

ECO:0000366

evidence based on logical inference from automatic annotation used in automatic assertion

GO:0005261

P

Seeded From UniProt

complete

enables

GO:0005261

cation channel activity

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008187

F

Seeded From UniProt

complete

involved_in

GO:0019076

viral release from host cell

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008187

P

Seeded From UniProt

complete

involved_in

GO:0032801

receptor catabolic process

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008187

P

Seeded From UniProt

complete

part_of

GO:0033644

host cell membrane

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR008187

C

Seeded From UniProt

complete

enables

GO:0042609

CD4 receptor binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR009032

F

Seeded From UniProt

complete

involved_in

GO:0019076

viral release from host cell

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000613417

P

Seeded From UniProt

complete

enables

GO:0005261

cation channel activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000613417

F

Seeded From UniProt

complete

involved_in

GO:0032801

receptor catabolic process

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000613417

P

Seeded From UniProt

complete

enables

GO:0042609

CD4 receptor binding

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000613417

F

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000613417

C

Seeded From UniProt

complete

involved_in

GO:0039587

suppression by virus of host tetherin activity

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000613417

P

Seeded From UniProt

complete

involved_in

GO:0039502

suppression by virus of host type I interferon-mediated signaling pathway

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000613417

P

Seeded From UniProt

complete

part_of

GO:0033644

host cell membrane

GO_REF:0000104

ECO:0000256

match to sequence model evidence used in automatic assertion

UniRule:UR000613417

C

Seeded From UniProt

complete

part_of

GO:0016021

integral component of membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0812

C

Seeded From UniProt

complete

part_of

GO:0016020

membrane

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0472

C

Seeded From UniProt

complete

involved_in

GO:0039503

suppression by virus of host innate immune response

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1090

P

Seeded From UniProt

complete

involved_in

GO:0016032

viral process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0945

P

Seeded From UniProt

complete

involved_in

GO:0039587

suppression by virus of host tetherin activity

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1084

P

Seeded From UniProt

complete

part_of

GO:0033644

host cell membrane

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1043
UniProtKB-SubCell:SL-0380

C

Seeded From UniProt

complete

involved_in

GO:0039502

suppression by virus of host type I interferon-mediated signaling pathway

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-1114

P

Seeded From UniProt

complete

involved_in

GO:0006811

ion transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0406

P

Seeded From UniProt

complete

involved_in

GO:0030683

evasion or tolerance by virus of host immune response

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0899

P

Seeded From UniProt

complete

GO:0019076

viral release from host cell

PMID:20529266[1]

ECO:0000314

P

Figure 3

complete
CACAO 3355

Notes

References

See Help:References for how to manage references in GONUTS.

  1. 1.0 1.1 Hauser, H et al. (2010) HIV-1 Vpu and HIV-2 Env counteract BST-2/tetherin by sequestration in a perinuclear compartment. Retrovirology 7 51 PubMed GONUTS page