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HUMAN:ZN423
Contents
Species (Taxon ID) | Homo sapiens (Human). (9606) | |
Gene Name(s) | ZNF423 (synonyms: KIAA0760, NPHP14, OAZ) | |
Protein Name(s) | Zinc finger protein 423
Olf1/EBF-associated zinc finger protein hOAZ Smad- and Olf-interacting zinc finger protein | |
External Links | ||
UniProt | Q2M1K9 | |
EMBL | BC112315 BC112317 AF221712 AB018303 | |
CCDS | CCDS32445.1 CCDS61930.1 | |
RefSeq | NP_001258549.1 NP_055884.2 XP_005255913.1 | |
UniGene | Hs.530930 Hs.744482 | |
PDB | 2MDG | |
PDBsum | 2MDG | |
ProteinModelPortal | Q2M1K9 | |
SMR | Q2M1K9 | |
BioGrid | 116718 | |
IntAct | Q2M1K9 | |
MINT | MINT-2819859 | |
STRING | 9606.ENSP00000262383 | |
PhosphoSite | Q2M1K9 | |
DMDM | 121941357 | |
PaxDb | Q2M1K9 | |
PRIDE | Q2M1K9 | |
DNASU | 23090 | |
Ensembl | ENST00000262383 ENST00000561648 ENST00000562520 ENST00000562871 ENST00000563137 | |
GeneID | 23090 | |
KEGG | hsa:23090 | |
UCSC | uc010vgn.3 | |
CTD | 23090 | |
GeneCards | GC16M049524 | |
HGNC | HGNC:16762 | |
HPA | HPA015258 | |
MIM | 604557 614844 | |
neXtProt | NX_Q2M1K9 | |
Orphanet | 2318 | |
PharmGKB | PA134903681 | |
eggNOG | COG5048 | |
GeneTree | ENSGT00800000124054 | |
HOGENOM | HOG000155793 | |
HOVERGEN | HBG052773 | |
InParanoid | Q2M1K9 | |
OMA | FIEHCQM | |
OrthoDB | EOG7NGQB0 | |
PhylomeDB | Q2M1K9 | |
TreeFam | TF331504 | |
ChiTaRS | ZNF423 | |
GeneWiki | ZNF423 | |
GenomeRNAi | 23090 | |
NextBio | 44239 | |
PRO | PR:Q2M1K9 | |
Proteomes | UP000005640 | |
Bgee | Q2M1K9 | |
CleanEx | HS_ZNF423 | |
ExpressionAtlas | Q2M1K9 | |
Genevisible | Q2M1K9 | |
GO | GO:0005634 GO:0003677 GO:0046872 GO:0030154 GO:0045892 GO:0007399 GO:0007219 GO:0030513 GO:0045893 GO:0006351 | |
Gene3D | 3.30.160.60 | |
InterPro | IPR007087 IPR015880 IPR013087 | |
Pfam | PF00096 | |
SMART | SM00355 | |
PROSITE | PS00028 PS50157 |
Annotations
Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
---|---|---|---|---|---|---|---|---|---|---|
involved_in |
GO:0120163 |
negative regulation of cold-induced thermogenesis |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0000981 |
DNA-binding transcription factor activity, RNA polymerase II-specific |
ECO:0005556 |
multiple sequence alignment evidence used in manual assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0045893 |
positive regulation of transcription, DNA-templated |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0045892 |
negative regulation of transcription, DNA-templated |
ECO:0000314 |
direct assay evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030513 |
positive regulation of BMP signaling pathway |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007219 |
Notch signaling pathway |
ECO:0000250 |
sequence similarity evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0006355 |
regulation of transcription, DNA-templated |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0037618 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005634 |
nucleus |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0000286 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0003700 |
DNA-binding transcription factor activity |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0037618 |
F |
Seeded From UniProt |
complete | ||
enables |
GO:0003677 |
DNA binding |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
FB:FBgn0003448 |
F |
Seeded From UniProt |
complete | ||
part_of |
GO:0005654 |
nucleoplasm |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0120163 |
negative regulation of cold-induced thermogenesis |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q80TS5 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0045893 |
positive regulation of transcription, DNA-templated |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q80TS5 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0030513 |
positive regulation of BMP signaling pathway |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q80TS5 |
P |
Seeded From UniProt |
complete | ||
involved_in |
GO:0007219 |
Notch signaling pathway |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q80TS5 |
P |
Seeded From UniProt |
complete | ||
part_of |
GO:0005634 |
nucleus |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q80TS5 |
C |
Seeded From UniProt |
complete | ||
enables |
GO:0003676 |
nucleic acid binding |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
enables |
GO:0003677 |
DNA binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007399 |
nervous system development |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
involved_in |
GO:0030154 |
cell differentiation |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
enables |
GO:0046872 |
metal ion binding |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
part_of |
GO:0005634 |
nucleus |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
involved_in |
GO:0007275 |
multicellular organism development |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Shao, M et al. (2016) Zfp423 Maintains White Adipocyte Identity through Suppression of the Beige Cell Thermogenic Gene Program. Cell Metab. 23 1167-1184 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Hata, A et al. (2000) OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways. Cell 100 229-40 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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