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HUMAN:VIGLN

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Species (Taxon ID) Homo sapiens (Human). (9606)
Gene Name(s) HDLBP (synonyms: HBP, VGL)
Protein Name(s) Vigilin

High density lipoprotein-binding protein HDL-binding protein

External Links
UniProt Q00341
EMBL M64098
AK300312
AC104841
BC001179
CCDS CCDS2547.1
CCDS58760.1
PIR A44125
RefSeq NP_001230829.1
NP_005327.1
NP_976221.1
XP_005247057.2
XP_005247058.2
XP_005247059.2
XP_005247060.2
XP_006712538.1
UniGene Hs.471851
Hs.732361
PDB 1VIG
1VIH
2CTE
2CTF
2CTJ
2CTK
2CTL
2CTM
PDBsum 1VIG
1VIH
2CTE
2CTF
2CTJ
2CTK
2CTL
2CTM
ProteinModelPortal Q00341
SMR Q00341
BioGrid 109319
IntAct Q00341
MINT MINT-1189333
STRING 9606.ENSP00000312042
PhosphoSite Q00341
DMDM 218511884
MaxQB Q00341
PaxDb Q00341
PeptideAtlas Q00341
PRIDE Q00341
DNASU 3069
Ensembl ENST00000427183
GeneID 3069
KEGG hsa:3069
UCSC uc002waz.3
CTD 3069
GeneCards GC02M242166
HGNC HGNC:4857
HPA CAB026457
HPA004189
MIM 142695
neXtProt NX_Q00341
PharmGKB PA29235
eggNOG NOG313207
GeneTree ENSGT00720000108747
HOGENOM HOG000007687
HOVERGEN HBG054107
InParanoid Q00341
OMA VVREAPW
OrthoDB EOG7KH9HW
PhylomeDB Q00341
TreeFam TF323767
ChiTaRS HDLBP
EvolutionaryTrace Q00341
GeneWiki HDLBP
GenomeRNAi 3069
NextBio 12141
PRO PR:Q00341
Proteomes UP000005640
Bgee Q00341
CleanEx HS_HDLBP
ExpressionAtlas Q00341
Genevestigator Q00341
GO GO:0005737
GO:0034364
GO:0005634
GO:0005886
GO:0008289
GO:0044822
GO:0008203
GO:0006869
Gene3D 3.30.1370.10
InterPro IPR004087
IPR004088
Pfam PF00013
SMART SM00322
SUPFAM SSF54791
PROSITE PS50084

Annotations

Qualifier GO ID GO term name Reference ECO ID ECO term name with/from Aspect Extension Notes Status

enables

GO:0045296

cadherin binding

PMID:25468996[1]

ECO:0007005

high throughput direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

PMID:22658674[2]

ECO:0007005

high throughput direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

PMID:22681889[3]

ECO:0007005

high throughput direct assay evidence used in manual assertion

F

Seeded From UniProt

complete

part_of

GO:0005829

cytosol

GO_REF:0000052

ECO:0000314

direct assay evidence used in manual assertion

C

Seeded From UniProt

complete

enables

GO:0003676

nucleic acid binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004087

F

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

GO_REF:0000002

ECO:0000256

match to sequence model evidence used in automatic assertion

InterPro:IPR004088
InterPro:IPR036612

F

Seeded From UniProt

complete

enables

GO:0008289

lipid binding

PMID:1318310[4]

ECO:0000304

author statement supported by traceable reference used in manual assertion

F

Seeded From UniProt

complete

involved_in

GO:0008203

cholesterol metabolic process

PMID:1318310[4]

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005886

plasma membrane

PMID:1318310[4]
Reactome:R-HSA-8858252

ECO:0000304

author statement supported by traceable reference used in manual assertion


C

Seeded From UniProt

complete

involved_in

GO:0034384

high-density lipoprotein particle clearance

Reactome:R-HSA-8964011

ECO:0000304

author statement supported by traceable reference used in manual assertion

P

Seeded From UniProt

complete

part_of

GO:0005737

cytoplasm

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0963
UniProtKB-SubCell:SL-0086

C

Seeded From UniProt

complete

involved_in

GO:0008203

cholesterol metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0153

P

Seeded From UniProt

complete

involved_in

GO:0008202

steroid metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0753

P

Seeded From UniProt

complete

involved_in

GO:0006869

lipid transport

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0445

P

Seeded From UniProt

complete

enables

GO:0003723

RNA binding

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0694

F

Seeded From UniProt

complete

part_of

GO:0034364

high-density lipoprotein particle

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0345

C

Seeded From UniProt

complete

involved_in

GO:0006629

lipid metabolic process

GO_REF:0000037

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0443

P

Seeded From UniProt

complete

part_of

GO:0005634

nucleus

GO_REF:0000037
GO_REF:0000039

ECO:0000322

imported manually asserted information used in automatic assertion

UniProtKB-KW:KW-0539
UniProtKB-SubCell:SL-0191

C

Seeded From UniProt

complete

Notes

References

See Help:References for how to manage references in GONUTS.

  1. Guo, Z et al. (2014) E-cadherin interactome complexity and robustness resolved by quantitative proteomics. Sci Signal 7 rs7 PubMed GONUTS page
  2. Castello, A et al. (2012) Insights into RNA biology from an atlas of mammalian mRNA-binding proteins. Cell 149 1393-406 PubMed GONUTS page
  3. Baltz, AG et al. (2012) The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Mol. Cell 46 674-90 PubMed GONUTS page
  4. 4.0 4.1 4.2 McKnight, GL et al. (1992) Cloning and expression of a cellular high density lipoprotein-binding protein that is up-regulated by cholesterol loading of cells. J. Biol. Chem. 267 12131-41 PubMed GONUTS page