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HUMAN:VGF
Contents
| Species (Taxon ID) | Homo sapiens (Human). (9606) | |
| Gene Name(s) | VGF | |
| Protein Name(s) | Neurosecretory protein VGF
Neuroendocrine regulatory peptide-1 NERP-1 Neuroendocrine regulatory peptide-2 NERP-2 Antimicrobial peptide VGF[554-577] | |
| External Links | ||
| UniProt | O15240 | |
| EMBL | Y12661 AC004876 CH471197 BC063835 | |
| CCDS | CCDS5712.1 | |
| RefSeq | NP_003369.2 XP_005250617.1 XP_005250618.1 | |
| UniGene | Hs.587325 | |
| ProteinModelPortal | O15240 | |
| BioGrid | 113268 | |
| IntAct | O15240 | |
| STRING | 9606.ENSP00000249330 | |
| PhosphoSite | O15240 | |
| MaxQB | O15240 | |
| PaxDb | O15240 | |
| PeptideAtlas | O15240 | |
| PRIDE | O15240 | |
| Ensembl | ENST00000249330 ENST00000445482 | |
| GeneID | 7425 | |
| KEGG | hsa:7425 | |
| UCSC | uc003uxx.4 | |
| CTD | 7425 | |
| GeneCards | GC07M100805 | |
| HGNC | HGNC:12684 | |
| HPA | HPA055177 | |
| MIM | 602186 | |
| neXtProt | NX_O15240 | |
| PharmGKB | PA37305 | |
| eggNOG | NOG75774 | |
| GeneTree | ENSGT00390000017745 | |
| HOGENOM | HOG000120127 | |
| HOVERGEN | HBG006806 | |
| InParanoid | O15240 | |
| OMA | LPEAHQF | |
| OrthoDB | EOG7W9RV0 | |
| PhylomeDB | O15240 | |
| TreeFam | TF338498 | |
| GenomeRNAi | 7425 | |
| NextBio | 29086 | |
| PRO | PR:O15240 | |
| Proteomes | UP000005640 | |
| Bgee | O15240 | |
| CleanEx | HS_VGF | |
| ExpressionAtlas | O15240 | |
| Genevestigator | O15240 | |
| GO | GO:0031410 GO:0005615 GO:0030133 GO:0042742 GO:0006091 GO:0042593 GO:0030073 GO:0001541 GO:0051591 GO:0009409 GO:0002021 GO:0032868 GO:0019953 | |
| InterPro | IPR026128 | |
| PANTHER | PTHR15159 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | ECO ID | ECO term name | with/from | Aspect | Extension | Notes | Status |
|---|---|---|---|---|---|---|---|---|---|---|
|
involved_in |
GO:0051591 |
response to cAMP |
ECO:0000270 |
expression pattern evidence used in manual assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031410 |
cytoplasmic vesicle |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005615 |
extracellular space |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0003674 |
molecular_function |
ECO:0000307 |
no biological data found used in manual assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005615 |
extracellular space |
ECO:0000318 |
biological aspect of ancestor evidence used in manual assertion |
PANTHER:PTN000389225 |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0043231 |
intracellular membrane-bounded organelle |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0005794 |
Golgi apparatus |
ECO:0000314 |
direct assay evidence used in manual assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0005184 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0005184 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0010469 |
regulation of signaling receptor activity |
ECO:0000366 |
evidence based on logical inference from automatic annotation used in automatic assertion |
GO:0008083 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0042593 |
glucose homeostasis |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q0VGU4 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0032868 |
response to insulin |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q0VGU4 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0030073 |
insulin secretion |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q0VGU4 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0019953 |
sexual reproduction |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q0VGU4 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0009409 |
response to cold |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q0VGU4 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0006091 |
generation of precursor metabolites and energy |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q0VGU4 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005184 |
neuropeptide hormone activity |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q0VGU4 |
F |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0002021 |
response to dietary excess |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q0VGU4 |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0001541 |
ovarian follicle development |
ECO:0000265 |
sequence orthology evidence used in automatic assertion |
UniProtKB:Q0VGU4 |
P |
Seeded From UniProt |
complete | ||
|
enables |
GO:0005184 |
neuropeptide hormone activity |
ECO:0000256 |
match to sequence model evidence used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0044267 |
cellular protein metabolic process |
Reactome:R-HSA-392499 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
involved_in |
GO:0043687 |
post-translational protein modification |
Reactome:R-HSA-597592 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
P |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005788 |
endoplasmic reticulum lumen |
Reactome:R-HSA-8952289 |
ECO:0000304 |
author statement supported by traceable reference used in manual assertion |
C |
Seeded From UniProt |
complete | ||
|
part_of |
GO:0005576 |
extracellular region |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
enables |
GO:0008083 |
growth factor activity |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
F |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0031410 |
cytoplasmic vesicle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
|
involved_in |
GO:0042742 |
defense response to bacterium |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
P |
Seeded From UniProt |
complete | |||
|
part_of |
GO:0030133 |
transport vesicle |
ECO:0000322 |
imported manually asserted information used in automatic assertion |
C |
Seeded From UniProt |
complete | |||
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Nagasaki, K et al. (1999) Staurosporine enhances cAMP-induced expression of neural-specific gene VGF and tyrosine hydroxylase. Neurosci. Lett. 267 177-80 PubMed GONUTS page
- ↑ Rindi, G et al. (2007) Peptide products of the neurotrophin-inducible gene vgf are produced in human neuroendocrine cells from early development and increase in hyperplasia and neoplasia. J. Clin. Endocrinol. Metab. 92 2811-5 PubMed GONUTS page
- ↑ Yuan, X & Desiderio, DM (2005) Human cerebrospinal fluid peptidomics. J Mass Spectrom 40 176-81 PubMed GONUTS page
- ↑ Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
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