HUMAN:VAMP7

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	VAMP7 (synonyms: SYBL1)
Protein Name(s)	Vesicle-associated membrane protein 7 VAMP-7 Synaptobrevin-like protein 1 Tetanus-insensitive VAMP Ti-VAMP
External Links
UniProt	P51809
EMBL	X92396 AJ271736 AJ549301 AJ295938 AK222794 BC056141 BI547528
CCDS	CCDS14770.4 CCDS48199.1 CCDS55548.1
RefSeq	NP_001138621.1 NP_001172112.1 NP_005629.1
UniGene	Hs.24167
PDB	2DMW
PDBsum	2DMW
ProteinModelPortal	P51809
SMR	P51809
BioGrid	112712
IntAct	P51809
STRING	9606.ENSP00000286448
PhosphoSite	P51809
DMDM	1723133
MaxQB	P51809
PaxDb	P51809
PRIDE	P51809
DNASU	6845
Ensembl	ENST00000262640 ENST00000286448 ENST00000460621
GeneID	6845
KEGG	hsa:6845
UCSC	uc004fnr.3 uc004fns.3 uc004fnt.3
CTD	6845
GeneCards	GC0XP155110
HGNC	HGNC:11486
HPA	HPA036733
MIM	300053
neXtProt	NX_P51809
PharmGKB	PA162408786
eggNOG	COG5143
GeneTree	ENSGT00510000047733
HOGENOM	HOG000042711
HOVERGEN	HBG006675
InParanoid	P51809
KO	K08515
OMA	CHDRIIY
OrthoDB	EOG75B87Z
PhylomeDB	P51809
TreeFam	TF323448
Reactome	REACT_19187 REACT_19287 REACT_19400
EvolutionaryTrace	P51809
GeneWiki	SYBL1
GenomeRNAi	6845
NextBio	26723
PRO	PR:P51809
Proteomes	UP000005640
Bgee	P51809
CleanEx	HS_VAMP7
ExpressionAtlas	P51809
Genevestigator	P51809
GO	GO:0045177 GO:0030054 GO:0009986 GO:0005737 GO:0005789 GO:0070062 GO:0005794 GO:0016021 GO:0043231 GO:0031902 GO:0005765 GO:0043005 GO:0048471 GO:0045335 GO:0030670 GO:0005886 GO:0031201 GO:0045202 GO:0030658 GO:0017156 GO:0008333 GO:0043308 GO:0006888 GO:0043001 GO:0061024 GO:0043312 GO:0006911 GO:0006892 GO:1900483 GO:0035493 GO:0034197 GO:0006906 GO:0048280 GO:0016192
Gene3D	3.30.450.50
InterPro	IPR011012 IPR010908 IPR001388
Pfam	PF13774 PF00957
PRINTS	PR00219
SUPFAM	SSF64356
PROSITE	PS50859 PS00417 PS50892

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
part_of	GO:0005802	trans-Golgi network	PMID:19745841^[1]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0043308	eosinophil degranulation	PMID:16677249^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0043312	neutrophil degranulation	PMID:16677249^[2]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0016020	membrane	PMID:16677249^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000775)\|part_of:(CL:0000771)	Seeded From UniProt	complete
part_of	GO:0035577	azurophil granule membrane	PMID:16677249^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000775)	Seeded From UniProt	complete
part_of	GO:0030667	secretory granule membrane	PMID:16677249^[2]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000771)	Seeded From UniProt	complete
involved_in	GO:0043320	natural killer cell degranulation	PMID:18042464^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0030141	secretory granule	PMID:18042464^[3]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000623)	Seeded From UniProt	complete
part_of	GO:0031091	platelet alpha granule	PMID:22589474^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0030027	lamellipodium	PMID:22589474^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0031143	pseudopodium	PMID:22589474^[4]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:1903595	positive regulation of histamine secretion by mast cell	PMID:18253931^[5]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0031201	SNARE complex	PMID:18253931^[5]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000097)	Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	PMID:18253931^[5]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000097)	Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:18253931^[5]	ECO:0000314	direct assay evidence used in manual assertion		C	part_of:(CL:0000097)	Seeded From UniProt	complete
part_of	GO:0070062	extracellular exosome	PMID:19056867^[6]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C	part_of:(UBERON:0001088)	Seeded From UniProt	complete
part_of	GO:0045335	phagocytic vesicle	PMID:15470500^[7]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P70280	C		Seeded From UniProt	complete
involved_in	GO:0043312	neutrophil degranulation	PMID:14993220^[8]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9JHW5	P		Seeded From UniProt	complete
involved_in	GO:0043308	eosinophil degranulation	PMID:14993220^[8]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9JHW5	P		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P70280	C		Seeded From UniProt	complete
part_of	GO:0031902	late endosome membrane	PMID:10459012^[9]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9JHW5	C		Seeded From UniProt	complete
part_of	GO:0031201	SNARE complex	PMID:15133481^[10]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9JHW5	C		Seeded From UniProt	complete
involved_in	GO:0017156	calcium ion regulated exocytosis	PMID:14993220^[8]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9JHW5	P		Seeded From UniProt	complete
involved_in	GO:0016192	vesicle-mediated transport	PMID:10888671^[11]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0008333	endosome to lysosome transport	PMID:10888671^[11]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006911	phagocytosis, engulfment	PMID:15133481^[10]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9JHW5	P		Seeded From UniProt	complete
involved_in	GO:0006906	vesicle fusion	PMID:10888671^[11]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	PMID:16495485^[12]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9JHW5	P		Seeded From UniProt	complete
part_of	GO:0005789	endoplasmic reticulum membrane	PMID:16495485^[12]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9JHW5	C		Seeded From UniProt	complete
part_of	GO:0005765	lysosomal membrane	PMID:17897319^[13]	ECO:0007005	high throughput direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005765	lysosomal membrane	PMID:10459012^[9]	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:Q9JHW5	C		Seeded From UniProt	complete
NOT\|involved_in	GO:0097352	autophagosome maturation	PMID:23217709^[14]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0031201	SNARE complex	PMID:21873635^[15]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0266186 PANTHER:PTN000473885 RGD:621558 SGD:S000004083 TAIR:locus:2080340 UniProtKB:P51809 dictyBase:DDB_G0284951	C		Seeded From UniProt	complete
involved_in	GO:0008333	endosome to lysosome transport	PMID:21873635^[15]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN001079719 RGD:621558 UniProtKB:P51809	P		Seeded From UniProt	complete
involved_in	GO:0006906	vesicle fusion	PMID:21873635^[15]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000473885 RGD:621558 SGD:S000004083 UniProtKB:P51809 dictyBase:DDB_G0284951	P		Seeded From UniProt	complete
involved_in	GO:0006887	exocytosis	PMID:21873635^[15]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000473885 RGD:621558	P		Seeded From UniProt	complete
enables	GO:0005484	SNAP receptor activity	PMID:21873635^[15]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0266186 PANTHER:PTN000473885 RGD:621558 SGD:S000004083	F		Seeded From UniProt	complete
enables	GO:0000149	SNARE binding	PMID:21873635^[15]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0266186 PANTHER:PTN000473885	F		Seeded From UniProt	complete
part_of	GO:0031201	SNARE complex	PMID:24550300^[16]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0043231	intracellular membrane-bounded organelle	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:1900483	regulation of protein targeting to vacuolar membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70280 ensembl:ENSMUSP00000052262	P		Seeded From UniProt	complete
involved_in	GO:0050775	positive regulation of dendrite morphogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70280 ensembl:ENSMUSP00000052262	P		Seeded From UniProt	complete
part_of	GO:0048471	perinuclear region of cytoplasm	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70280 ensembl:ENSMUSP00000052262	C		Seeded From UniProt	complete
part_of	GO:0045335	phagocytic vesicle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70280 ensembl:ENSMUSP00000052262	C		Seeded From UniProt	complete
part_of	GO:0045177	apical part of cell	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70280 ensembl:ENSMUSP00000052262	C		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70280 ensembl:ENSMUSP00000052262	C		Seeded From UniProt	complete
involved_in	GO:0043001	Golgi to plasma membrane protein transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70280 ensembl:ENSMUSP00000052262	P		Seeded From UniProt	complete
involved_in	GO:0035493	SNARE complex assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70280 ensembl:ENSMUSP00000052262	P		Seeded From UniProt	complete
part_of	GO:0031143	pseudopodium	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70280 ensembl:ENSMUSP00000052262	C		Seeded From UniProt	complete
part_of	GO:0030133	transport vesicle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70280 ensembl:ENSMUSP00000052262	C		Seeded From UniProt	complete
part_of	GO:0030027	lamellipodium	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70280 ensembl:ENSMUSP00000052262	C		Seeded From UniProt	complete
part_of	GO:0009986	cell surface	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70280 ensembl:ENSMUSP00000052262	C		Seeded From UniProt	complete
part_of	GO:0005794	Golgi apparatus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P70280 ensembl:ENSMUSP00000052262	C		Seeded From UniProt	complete
part_of	GO:0098686	hippocampal mossy fiber to CA3 synapse	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9JHW5 ensembl:ENSRNOP00000011065	C		Seeded From UniProt	complete
involved_in	GO:0048280	vesicle fusion with Golgi apparatus	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9JHW5 ensembl:ENSRNOP00000011065	P		Seeded From UniProt	complete
involved_in	GO:0047496	vesicle transport along microtubule	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9JHW5 ensembl:ENSRNOP00000011065	P		Seeded From UniProt	complete
involved_in	GO:0043312	neutrophil degranulation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9JHW5 ensembl:ENSRNOP00000011065	P		Seeded From UniProt	complete
involved_in	GO:0043308	eosinophil degranulation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9JHW5 ensembl:ENSRNOP00000011065	P		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9JHW5 ensembl:ENSRNOP00000011065	C		Seeded From UniProt	complete
involved_in	GO:0034197	triglyceride transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9JHW5 ensembl:ENSRNOP00000011065	P		Seeded From UniProt	complete
part_of	GO:0031902	late endosome membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9JHW5 ensembl:ENSRNOP00000011065	C		Seeded From UniProt	complete
part_of	GO:0031201	SNARE complex	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9JHW5 ensembl:ENSRNOP00000011065	C		Seeded From UniProt	complete
part_of	GO:0030285	integral component of synaptic vesicle membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9JHW5 ensembl:ENSRNOP00000011065	C		Seeded From UniProt	complete
enables	GO:0019905	syntaxin binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9JHW5 ensembl:ENSRNOP00000011065	F		Seeded From UniProt	complete
involved_in	GO:0017156	calcium ion regulated exocytosis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9JHW5 ensembl:ENSRNOP00000011065	P		Seeded From UniProt	complete
involved_in	GO:0016192	vesicle-mediated transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9JHW5 ensembl:ENSRNOP00000011065	P		Seeded From UniProt	complete
involved_in	GO:0008333	endosome to lysosome transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9JHW5 ensembl:ENSRNOP00000011065	P		Seeded From UniProt	complete
part_of	GO:0008021	synaptic vesicle	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9JHW5 ensembl:ENSRNOP00000011065	C		Seeded From UniProt	complete
involved_in	GO:0006911	phagocytosis, engulfment	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9JHW5 ensembl:ENSRNOP00000011065	P		Seeded From UniProt	complete
involved_in	GO:0006906	vesicle fusion	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9JHW5 ensembl:ENSRNOP00000011065	P		Seeded From UniProt	complete
involved_in	GO:0006888	endoplasmic reticulum to Golgi vesicle-mediated transport	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9JHW5 ensembl:ENSRNOP00000011065	P		Seeded From UniProt	complete
involved_in	GO:0006887	exocytosis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9JHW5 ensembl:ENSRNOP00000011065	P		Seeded From UniProt	complete
part_of	GO:0005789	endoplasmic reticulum membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9JHW5 ensembl:ENSRNOP00000011065	C		Seeded From UniProt	complete
part_of	GO:0005765	lysosomal membrane	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9JHW5 ensembl:ENSRNOP00000011065	C		Seeded From UniProt	complete
enables	GO:0005484	SNAP receptor activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:Q9JHW5 ensembl:ENSRNOP00000011065	F		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001388	C		Seeded From UniProt	complete
involved_in	GO:0016192	vesicle-mediated transport	GO_REF:0000002	ECO:0000256	match to sequence model evidence used in automatic assertion	InterPro:IPR001388	P		Seeded From UniProt	complete
involved_in	GO:0061024	membrane organization	Reactome:R-HSA-199991	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0030665	clathrin-coated vesicle membrane	Reactome:R-HSA-8871194 Reactome:R-HSA-8871193 Reactome:R-HSA-8869438 Reactome:R-HSA-8868661 Reactome:R-HSA-8868660 Reactome:R-HSA-8868659 Reactome:R-HSA-8868658	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
involved_in	GO:0006892	post-Golgi vesicle-mediated transport	Reactome:R-HSA-199992	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	Reactome:R-HSA-8868661 Reactome:R-HSA-8868651 Reactome:R-HSA-8868648 Reactome:R-HSA-8868236 Reactome:R-HSA-8868230 Reactome:R-HSA-8868072 Reactome:R-HSA-8868071 Reactome:R-HSA-8867756 Reactome:R-HSA-8867754 Reactome:R-HSA-8863718 Reactome:R-HSA-376357	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005765	lysosomal membrane	Reactome:R-HSA-376357	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0043005	neuron projection	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0771 UniProtKB-SubCell:SL-0261	C		Seeded From UniProt	complete
involved_in	GO:0006887	exocytosis	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0268	P		Seeded From UniProt	complete
part_of	GO:0016021	integral component of membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0812	C		Seeded From UniProt	complete
part_of	GO:0005794	Golgi apparatus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0333 UniProtKB-SubCell:SL-0132	C		Seeded From UniProt	complete
part_of	GO:0030054	cell junction	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0965	C		Seeded From UniProt	complete
involved_in	GO:0015031	protein transport	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0653	P		Seeded From UniProt	complete
part_of	GO:0005764	lysosome	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0458	C		Seeded From UniProt	complete
part_of	GO:0005783	endoplasmic reticulum	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0256	C		Seeded From UniProt	complete
part_of	GO:0045202	synapse	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0770	C		Seeded From UniProt	complete
part_of	GO:0005768	endosome	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0967	C		Seeded From UniProt	complete
part_of	GO:0031410	cytoplasmic vesicle	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0968	C		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
part_of	GO:0005765	lysosomal membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0157	C		Seeded From UniProt	complete
part_of	GO:0005789	endoplasmic reticulum membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0097	C		Seeded From UniProt	complete
part_of	GO:0030658	transport vesicle membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0245	C		Seeded From UniProt	complete
part_of	GO:0030670	phagocytic vesicle membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0205	C		Seeded From UniProt	complete
part_of	GO:0031902	late endosome membrane	GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-SubCell:SL-0151	C		Seeded From UniProt	complete
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Notes

References

See Help:References for how to manage references in GONUTS.

↑ Burgo, A et al. (2009) Role of Varp, a Rab21 exchange factor and TI-VAMP/VAMP7 partner, in neurite growth. EMBO Rep. 10 1117-24 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 Logan, MR et al. (2006) A critical role for vesicle-associated membrane protein-7 in exocytosis from human eosinophils and neutrophils. Allergy 61 777-84 PubMed GONUTS page
↑ ^3.0 ^3.1 Marcet-Palacios, M et al. (2008) Vesicle-associated membrane protein 7 (VAMP-7) is essential for target cell killing in a natural killer cell line. Biochem. Biophys. Res. Commun. 366 617-23 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 Peters, CG et al. (2012) Granule exocytosis is required for platelet spreading: differential sorting of α-granules expressing VAMP-7. Blood 120 199-206 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 ^5.3 Sander, LE et al. (2008) Vesicle associated membrane protein (VAMP)-7 and VAMP-8, but not VAMP-2 or VAMP-3, are required for activation-induced degranulation of mature human mast cells. Eur. J. Immunol. 38 855-63 PubMed GONUTS page
↑ Gonzales, PA et al. (2009) Large-scale proteomics and phosphoproteomics of urinary exosomes. J. Am. Soc. Nephrol. 20 363-79 PubMed GONUTS page
↑ Braun, V et al. (2004) TI-VAMP/VAMP7 is required for optimal phagocytosis of opsonised particles in macrophages. EMBO J. 23 4166-76 PubMed GONUTS page
↑ ^8.0 ^8.1 ^8.2 Rao, SK et al. (2004) Identification of SNAREs involved in synaptotagmin VII-regulated lysosomal exocytosis. J. Biol. Chem. 279 20471-9 PubMed GONUTS page
↑ ^9.0 ^9.1 Advani, RJ et al. (1999) VAMP-7 mediates vesicular transport from endosomes to lysosomes. J. Cell Biol. 146 765-76 PubMed GONUTS page
↑ ^10.0 ^10.1 Pryor, PR et al. (2004) Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events. EMBO Rep. 5 590-5 PubMed GONUTS page
↑ ^11.0 ^11.1 ^11.2 Ward, DM et al. (2000) Syntaxin 7 and VAMP-7 are soluble N-ethylmaleimide-sensitive factor attachment protein receptors required for late endosome-lysosome and homotypic lysosome fusion in alveolar macrophages. Mol. Biol. Cell 11 2327-33 PubMed GONUTS page
↑ ^12.0 ^12.1 Siddiqi, SA et al. (2006) Vesicle-associated membrane protein 7 is expressed in intestinal ER. J. Cell. Sci. 119 943-50 PubMed GONUTS page
↑ Schröder, B et al. (2007) Integral and associated lysosomal membrane proteins. Traffic 8 1676-86 PubMed GONUTS page
↑ Itakura, E et al. (2012) The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes. Cell 151 1256-69 PubMed GONUTS page
↑ ^15.0 ^15.1 ^15.2 ^15.3 ^15.4 ^15.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Pirooz, SD et al. (2014) UVRAG is required for virus entry through combinatorial interaction with the class C-Vps complex and SNAREs. Proc. Natl. Acad. Sci. U.S.A. 111 2716-21 PubMed GONUTS page

[PMID:19745841-1] Burgo, A et al. (2009) Role of Varp, a Rab21 exchange factor and TI-VAMP/VAMP7 partner, in neurite growth. EMBO Rep. 10 1117-24 PubMed GONUTS page

[PMID:16677249-2] 2.0 ^2.1 ^2.2 ^2.3 ^2.4 Logan, MR et al. (2006) A critical role for vesicle-associated membrane protein-7 in exocytosis from human eosinophils and neutrophils. Allergy 61 777-84 PubMed GONUTS page

[PMID:18042464-3] 3.0 ^3.1 Marcet-Palacios, M et al. (2008) Vesicle-associated membrane protein 7 (VAMP-7) is essential for target cell killing in a natural killer cell line. Biochem. Biophys. Res. Commun. 366 617-23 PubMed GONUTS page

[PMID:22589474-4] 4.0 ^4.1 ^4.2 Peters, CG et al. (2012) Granule exocytosis is required for platelet spreading: differential sorting of α-granules expressing VAMP-7. Blood 120 199-206 PubMed GONUTS page

[PMID:18253931-5] 5.0 ^5.1 ^5.2 ^5.3 Sander, LE et al. (2008) Vesicle associated membrane protein (VAMP)-7 and VAMP-8, but not VAMP-2 or VAMP-3, are required for activation-induced degranulation of mature human mast cells. Eur. J. Immunol. 38 855-63 PubMed GONUTS page

[PMID:19056867-6] Gonzales, PA et al. (2009) Large-scale proteomics and phosphoproteomics of urinary exosomes. J. Am. Soc. Nephrol. 20 363-79 PubMed GONUTS page

[PMID:15470500-7] Braun, V et al. (2004) TI-VAMP/VAMP7 is required for optimal phagocytosis of opsonised particles in macrophages. EMBO J. 23 4166-76 PubMed GONUTS page

[PMID:14993220-8] 8.0 ^8.1 ^8.2 Rao, SK et al. (2004) Identification of SNAREs involved in synaptotagmin VII-regulated lysosomal exocytosis. J. Biol. Chem. 279 20471-9 PubMed GONUTS page

[PMID:10459012-9] 9.0 ^9.1 Advani, RJ et al. (1999) VAMP-7 mediates vesicular transport from endosomes to lysosomes. J. Cell Biol. 146 765-76 PubMed GONUTS page

[PMID:15133481-10] 10.0 ^10.1 Pryor, PR et al. (2004) Combinatorial SNARE complexes with VAMP7 or VAMP8 define different late endocytic fusion events. EMBO Rep. 5 590-5 PubMed GONUTS page

[PMID:10888671-11] 11.0 ^11.1 ^11.2 Ward, DM et al. (2000) Syntaxin 7 and VAMP-7 are soluble N-ethylmaleimide-sensitive factor attachment protein receptors required for late endosome-lysosome and homotypic lysosome fusion in alveolar macrophages. Mol. Biol. Cell 11 2327-33 PubMed GONUTS page

[PMID:16495485-12] 12.0 ^12.1 Siddiqi, SA et al. (2006) Vesicle-associated membrane protein 7 is expressed in intestinal ER. J. Cell. Sci. 119 943-50 PubMed GONUTS page

[PMID:17897319-13] Schröder, B et al. (2007) Integral and associated lysosomal membrane proteins. Traffic 8 1676-86 PubMed GONUTS page

[PMID:23217709-14] Itakura, E et al. (2012) The hairpin-type tail-anchored SNARE syntaxin 17 targets to autophagosomes for fusion with endosomes/lysosomes. Cell 151 1256-69 PubMed GONUTS page

[PMID:21873635-15] 15.0 ^15.1 ^15.2 ^15.3 ^15.4 ^15.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:24550300-16] Pirooz, SD et al. (2014) UVRAG is required for virus entry through combinatorial interaction with the class C-Vps complex and SNAREs. Proc. Natl. Acad. Sci. U.S.A. 111 2716-21 PubMed GONUTS page

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HUMAN:VAMP7

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