HUMAN:UBE2B

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	UBE2B (synonyms: RAD6B)
Protein Name(s)	Ubiquitin-conjugating enzyme E2 B RAD6 homolog B HR6B hHR6B Ubiquitin carrier protein B Ubiquitin-conjugating enzyme E2-17 kDa Ubiquitin-protein ligase B
External Links
UniProt	P63146
EMBL	M74525 X53251 BT007071 CR407634 DQ090910 AK312012 CH471062 CH471062 BC005979 BC008404 BC008470
CCDS	CCDS4174.1
PIR	B41222
RefSeq	NP_003328.1
UniGene	Hs.612096 Hs.730071
PDB	1JAS 1NXA 2Y4W 2YB6 2YBF
PDBsum	1JAS 1NXA 2Y4W 2YB6 2YBF
ProteinModelPortal	P63146
SMR	P63146
BioGrid	113168
DIP	DIP-29832N
IntAct	P63146
MINT	MINT-97455
STRING	9606.ENSP00000265339
DMDM	52783814
MaxQB	P63146
PaxDb	P63146
PRIDE	P63146
DNASU	7320
Ensembl	ENST00000265339
GeneID	7320
KEGG	hsa:7320
UCSC	uc003kzh.3
CTD	7320
GeneCards	GC05P133706
HGNC	HGNC:12473
MIM	179095
neXtProt	NX_P63146
PharmGKB	PA37123
eggNOG	COG5078
GeneTree	ENSGT00730000110565
HOGENOM	HOG000233454
HOVERGEN	HBG063308
InParanoid	P63146
KO	K10574
OMA	IVEQSWV
OrthoDB	EOG7M0NTH
PhylomeDB	P63146
TreeFam	TF101128
Reactome	REACT_75842
SignaLink	P63146
UniPathway	UPA00143
ChiTaRS	UBE2B
EvolutionaryTrace	P63146
GeneWiki	UBE2B
GenomeRNAi	7320
NextBio	28622
PRO	PR:P63146
Proteomes	UP000005640
Bgee	P63146
CleanEx	HS_UBE2B
ExpressionAtlas	P63146
Genevestigator	P63146
GO	GO:0000785 GO:0005737 GO:0033503 GO:0000790 GO:0005634 GO:0005886 GO:0005657 GO:0001741 GO:0016881 GO:0005524 GO:0031625 GO:0004842 GO:0060070 GO:0006974 GO:0032869 GO:0051026 GO:0006281 GO:0033522 GO:0070076 GO:0001701 GO:0006344 GO:0043066 GO:0043951 GO:0033128 GO:0010845 GO:0006301 GO:0043161 GO:0051865 GO:0070979 GO:0070936 GO:0070534 GO:0006513 GO:0000209 GO:0050821 GO:0016567 GO:0042493 GO:0001666 GO:0009411 GO:0007288 GO:0007283 GO:0070193 GO:0006511
Gene3D	3.10.110.10
InterPro	IPR000608 IPR023313 IPR016135
Pfam	PF00179
SUPFAM	SSF54495
PROSITE	PS00183 PS50127

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0070979	protein K11-linked ubiquitination	PMID:20061386^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0070936	protein K48-linked ubiquitination	PMID:20061386^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0070534	protein K63-linked ubiquitination	PMID:20061386^[1]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0090263	positive regulation of canonical Wnt signaling pathway	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P63147	P		Seeded From UniProt	complete
involved_in	GO:0051865	protein autoubiquitination	PMID:19123975^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0050821	protein stabilization	PMID:18339854^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	has_input:(UniProtKB:P35222)	Seeded From UniProt	complete
involved_in	GO:0043951	negative regulation of cAMP-mediated signaling	PMID:10373550^[4]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	PMID:10373550^[4]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0042493	response to drug	PMID:14981545^[5]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0033522	histone H2A ubiquitination	PMID:18339854^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0033503	HULC complex	PMID:19410543^[6]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0031625	ubiquitin protein ligase binding	PMID:10908344^[7]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q9NS91	F		Seeded From UniProt	complete
enables	GO:0031625	ubiquitin protein ligase binding	PMID:18363965^[8]	ECO:0000353	physical interaction evidence used in manual assertion	UniProtKB:Q9NS91	F		Seeded From UniProt	complete
involved_in	GO:0016567	protein ubiquitination	PMID:10373550^[4]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0016567	protein ubiquitination	PMID:19123975^[2]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0009411	response to UV	PMID:1717990^[9]	ECO:0000316	genetic interaction evidence used in manual assertion	UniProtKB:P06104	P		Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	PMID:14981545^[5]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006513	protein monoubiquitination	PMID:18339854^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	has_input:(UniProtKB:P35222)	Seeded From UniProt	complete
involved_in	GO:0006511	ubiquitin-dependent protein catabolic process	PMID:10373550^[4]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006511	ubiquitin-dependent protein catabolic process	PMID:1559696^[10]	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006301	postreplication repair	PMID:14981545^[5]	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006301	postreplication repair	PMID:1559696^[10]	ECO:0000303	author statement without traceable support used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	PMID:1717990^[9]	ECO:0000316	genetic interaction evidence used in manual assertion	UniProtKB:P06104	P		Seeded From UniProt	complete
part_of	GO:0005737	cytoplasm	PMID:18339854^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005657	replication fork	PMID:18363965^[8]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:18339854^[3]	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0004842	ubiquitin-protein transferase activity	PMID:18339854^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0004842	ubiquitin-protein transferase activity	PMID:20061386^[1]	ECO:0000314	direct assay evidence used in manual assertion		F	has_direct_input:(UniProtKB:P35222)	Seeded From UniProt	complete
enables	GO:0004842	ubiquitin-protein transferase activity	PMID:10373550^[4]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
enables	GO:0004842	ubiquitin-protein transferase activity	PMID:19123975^[2]	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
part_of	GO:0000785	chromatin	GO_REF:0000024	ECO:0000250	sequence similarity evidence used in manual assertion	UniProtKB:P63147	C		Seeded From UniProt	complete
involved_in	GO:0000209	protein polyubiquitination	PMID:18339854^[3]	ECO:0000315	mutant phenotype evidence used in manual assertion		P	has_input:(UniProtKB:P35222)	Seeded From UniProt	complete
enables	GO:0061631	ubiquitin conjugating enzyme activity	PMID:21873635^[11]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:102944 MGI:MGI:102959 PANTHER:PTN000630651 PomBase:SPAC18B11.07c UniProtKB:P49459 WB:WBGene00006701	F		Seeded From UniProt	complete
involved_in	GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process	PMID:21873635^[11]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0004436 PANTHER:PTN000630651 PomBase:SPAC18B11.07c UniProtKB:P63146	P		Seeded From UniProt	complete
part_of	GO:0033503	HULC complex	PMID:21873635^[11]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000630652 PomBase:SPAC18B11.07c UniProtKB:P49459 UniProtKB:P63146	C		Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	PMID:21873635^[11]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	FB:FBgn0004436 PANTHER:PTN000630651 UniProtKB:P49459 UniProtKB:P63146 WB:WBGene00006701	P		Seeded From UniProt	complete
part_of	GO:0000790	nuclear chromatin	PMID:21873635^[11]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	MGI:MGI:102944 MGI:MGI:102959 PANTHER:PTN000630652 SGD:S000003026	C		Seeded From UniProt	complete
involved_in	GO:0000209	protein polyubiquitination	PMID:21873635^[11]	ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000630651 SGD:S000003026 UniProtKB:P63146	P		Seeded From UniProt	complete
involved_in	GO:0090263	positive regulation of canonical Wnt signaling pathway	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63147 ensembl:ENSMUSP00000020657	P		Seeded From UniProt	complete
involved_in	GO:0070193	synaptonemal complex organization	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63147 ensembl:ENSMUSP00000020657	P		Seeded From UniProt	complete
involved_in	GO:0070076	histone lysine demethylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63147 ensembl:ENSMUSP00000020657	P		Seeded From UniProt	complete
enables	GO:0061631	ubiquitin conjugating enzyme activity	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63147 ensembl:ENSMUSP00000020657	F		Seeded From UniProt	complete
involved_in	GO:0051026	chiasma assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63147 ensembl:ENSMUSP00000020657	P		Seeded From UniProt	complete
involved_in	GO:0045141	meiotic telomere clustering	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63147 ensembl:ENSMUSP00000020657	P		Seeded From UniProt	complete
involved_in	GO:0043066	negative regulation of apoptotic process	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63147 ensembl:ENSMUSP00000020657	P		Seeded From UniProt	complete
involved_in	GO:0033128	negative regulation of histone phosphorylation	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63147 ensembl:ENSMUSP00000020657	P		Seeded From UniProt	complete
enables	GO:0031625	ubiquitin protein ligase binding	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63147 ensembl:ENSMUSP00000020657	F		Seeded From UniProt	complete
involved_in	GO:0031056	regulation of histone modification	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63147 ensembl:ENSMUSP00000020657	P		Seeded From UniProt	complete
involved_in	GO:0010845	positive regulation of reciprocal meiotic recombination	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63147 ensembl:ENSMUSP00000020657	P		Seeded From UniProt	complete
involved_in	GO:0007288	sperm axoneme assembly	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63147 ensembl:ENSMUSP00000020657	P		Seeded From UniProt	complete
involved_in	GO:0007283	spermatogenesis	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63147 ensembl:ENSMUSP00000020657	P		Seeded From UniProt	complete
involved_in	GO:0006344	maintenance of chromatin silencing	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63147 ensembl:ENSMUSP00000020657	P		Seeded From UniProt	complete
part_of	GO:0001741	XY body	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63147 ensembl:ENSMUSP00000020657	C		Seeded From UniProt	complete
involved_in	GO:0001701	in utero embryonic development	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63147 ensembl:ENSMUSP00000020657	P		Seeded From UniProt	complete
part_of	GO:0000790	nuclear chromatin	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63147 ensembl:ENSMUSP00000020657	C		Seeded From UniProt	complete
part_of	GO:0000785	chromatin	GO_REF:0000107	ECO:0000265	sequence orthology evidence used in automatic assertion	UniProtKB:P63147 ensembl:ENSMUSP00000020657	C		Seeded From UniProt	complete
involved_in	GO:0007283	spermatogenesis	PMID:18497339^[12]	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0042769	DNA damage response, detection of DNA damage	Reactome:R-HSA-110314	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0016567	protein ubiquitination	Reactome:R-HSA-8866654 Reactome:R-HSA-8866652	ECO:0000304	author statement supported by traceable reference used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005654	nucleoplasm	Reactome:R-HSA-8943041 Reactome:R-HSA-8943040 Reactome:R-HSA-8943007 Reactome:R-HSA-8943003 Reactome:R-HSA-8942101 Reactome:R-HSA-8942099 Reactome:R-HSA-8852130 Reactome:R-HSA-5652009 Reactome:R-HSA-5652005	ECO:0000304	author statement supported by traceable reference used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F		Seeded From UniProt	complete
enables	GO:0005524	ATP binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0067	F		Seeded From UniProt	complete
part_of	GO:0016020	membrane	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0472	C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
involved_in	GO:0006974	cellular response to DNA damage stimulus	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0227	P		Seeded From UniProt	complete
enables	GO:0000166	nucleotide binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0547	F		Seeded From UniProt	complete
part_of	GO:0005886	plasma membrane	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-1003 UniProtKB-SubCell:SL-0039	C		Seeded From UniProt	complete
involved_in	GO:0006281	DNA repair	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0234	P		Seeded From UniProt	complete
involved_in	GO:0016567	protein ubiquitination	GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniPathway:UPA00143	P		Seeded From UniProt	complete
edit table

Notes

References

See Help:References for how to manage references in GONUTS.

↑ ^1.0 ^1.1 ^1.2 ^1.3 David, Y et al. (2010) The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines. J. Biol. Chem. 285 8595-604 PubMed GONUTS page
↑ ^2.0 ^2.1 ^2.2 Ryu, KS et al. (2008) Direct characterization of E2-dependent target specificity and processivity using an artificial p27-linker-E2 ubiquitination system. BMB Rep 41 852-7 PubMed GONUTS page
↑ ^3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 Shekhar, MP et al. (2008) Rad6B is a positive regulator of beta-catenin stabilization. Cancer Res. 68 1741-50 PubMed GONUTS page
↑ ^4.0 ^4.1 ^4.2 ^4.3 ^4.4 Pati, D et al. (1999) Human Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced transcription for proteolysis. Mol. Cell. Biol. 19 5001-13 PubMed GONUTS page
↑ ^5.0 ^5.1 ^5.2 Lyakhovich, A & Shekhar, MP (2004) RAD6B overexpression confers chemoresistance: RAD6 expression during cell cycle and its redistribution to chromatin during DNA damage-induced response. Oncogene 23 3097-106 PubMed GONUTS page
↑ Kim, J et al. (2009) RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells. Cell 137 459-71 PubMed GONUTS page
↑ Xin, H et al. (2000) The human RAD18 gene product interacts with HHR6A and HHR6B. Nucleic Acids Res. 28 2847-54 PubMed GONUTS page
↑ ^8.0 ^8.1 Tsuji, Y et al. (2008) Recognition of forked and single-stranded DNA structures by human RAD18 complexed with RAD6B protein triggers its recruitment to stalled replication forks. Genes Cells 13 343-54 PubMed GONUTS page
↑ ^9.0 ^9.1 Koken, MH et al. (1991) Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6. Proc. Natl. Acad. Sci. U.S.A. 88 8865-9 PubMed GONUTS page
↑ ^10.0 ^10.1 Koken, MH et al. (1992) Localization of two human homologs, HHR6A and HHR6B, of the yeast DNA repair gene RAD6 to chromosomes Xq24-q25 and 5q23-q31. Genomics 12 447-53 PubMed GONUTS page
↑ ^11.0 ^11.1 ^11.2 ^11.3 ^11.4 ^11.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page
↑ Suryavathi, V et al. () Novel variants in UBE2B gene and idiopathic male infertility. J. Androl. 29 564-71 PubMed GONUTS page

[PMID:20061386-1] 1.0 ^1.1 ^1.2 ^1.3 David, Y et al. (2010) The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines. J. Biol. Chem. 285 8595-604 PubMed GONUTS page

[PMID:19123975-2] 2.0 ^2.1 ^2.2 Ryu, KS et al. (2008) Direct characterization of E2-dependent target specificity and processivity using an artificial p27-linker-E2 ubiquitination system. BMB Rep 41 852-7 PubMed GONUTS page

[PMID:18339854-3] 3.0 ^3.1 ^3.2 ^3.3 ^3.4 ^3.5 ^3.6 Shekhar, MP et al. (2008) Rad6B is a positive regulator of beta-catenin stabilization. Cancer Res. 68 1741-50 PubMed GONUTS page

[PMID:10373550-4] 4.0 ^4.1 ^4.2 ^4.3 ^4.4 Pati, D et al. (1999) Human Cdc34 and Rad6B ubiquitin-conjugating enzymes target repressors of cyclic AMP-induced transcription for proteolysis. Mol. Cell. Biol. 19 5001-13 PubMed GONUTS page

[PMID:14981545-5] 5.0 ^5.1 ^5.2 Lyakhovich, A & Shekhar, MP (2004) RAD6B overexpression confers chemoresistance: RAD6 expression during cell cycle and its redistribution to chromatin during DNA damage-induced response. Oncogene 23 3097-106 PubMed GONUTS page

[PMID:19410543-6] Kim, J et al. (2009) RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells. Cell 137 459-71 PubMed GONUTS page

[PMID:10908344-7] Xin, H et al. (2000) The human RAD18 gene product interacts with HHR6A and HHR6B. Nucleic Acids Res. 28 2847-54 PubMed GONUTS page

[PMID:18363965-8] 8.0 ^8.1 Tsuji, Y et al. (2008) Recognition of forked and single-stranded DNA structures by human RAD18 complexed with RAD6B protein triggers its recruitment to stalled replication forks. Genes Cells 13 343-54 PubMed GONUTS page

[PMID:1717990-9] 9.0 ^9.1 Koken, MH et al. (1991) Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6. Proc. Natl. Acad. Sci. U.S.A. 88 8865-9 PubMed GONUTS page

[PMID:1559696-10] 10.0 ^10.1 Koken, MH et al. (1992) Localization of two human homologs, HHR6A and HHR6B, of the yeast DNA repair gene RAD6 to chromosomes Xq24-q25 and 5q23-q31. Genomics 12 447-53 PubMed GONUTS page

[PMID:21873635-11] 11.0 ^11.1 ^11.2 ^11.3 ^11.4 ^11.5 Gaudet, P et al. (2011) Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics 12 449-62 PubMed GONUTS page

[PMID:18497339-12] Suryavathi, V et al. () Novel variants in UBE2B gene and idiopathic male infertility. J. Androl. 29 564-71 PubMed GONUTS page

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]

[9]

[10]

[11]

[12]

HUMAN:UBE2B

Contents

Annotations

Notes

References

a

c

d

e

h

i

m

n

o

p

r

s

t

u

v

x

Navigation menu

Personal tools

Namespaces

Variants

Views

More

Search

Navigation

Cacao

Links

Tools