HUMAN:TTC3

Species (Taxon ID)	Homo sapiens (Human). (9606)
Gene Name(s)	TTC3 (synonyms: DCRR1, RNF105, TPRD)
Protein Name(s)	E3 ubiquitin-protein ligase TTC3 Protein DCRR1 RING finger protein 105 TPR repeat protein D Tetratricopeptide repeat protein 3 TPR repeat protein 3
External Links
UniProt	P53804
EMBL	D83077 D84294 D84295 D84296 AP001429 AP001432 CH471079 CH471079 CH471079 CH471079 CH471079 CH471079 CH471079 CH471079 BC063033 BC092466 BC137345 AK291992 D83327 AJ001866
CCDS	CCDS13651.1
PIR	JC5020
RefSeq	NP_001001894.1 NP_003307.3
UniGene	Hs.368214
ProteinModelPortal	P53804
BioGrid	113118
IntAct	P53804
MINT	MINT-1181179
PhosphoSite	P53804
DMDM	313104040
MaxQB	P53804
PaxDb	P53804
PRIDE	P53804
Ensembl	ENST00000354749 ENST00000355666 ENST00000399017
GeneID	7267
KEGG	hsa:7267
UCSC	uc002yvz.3
CTD	7267
GeneCards	GC21P038445
H-InvDB	HIX0027791 HIX0041033 HIX0148527
HGNC	HGNC:12393
HPA	HPA016810 HPA023964
MIM	602259
neXtProt	NX_P53804
PharmGKB	PA37058
eggNOG	NOG248683
GeneTree	ENSGT00530000063254
HOVERGEN	HBG007494
InParanoid	P53804
KO	K15712
OMA	FPCYNST
PhylomeDB	P53804
TreeFam	TF333981
UniPathway	UPA00143
ChiTaRS	TTC3
GeneWiki	TTC3
GenomeRNAi	7267
NextBio	28411
PRO	PR:P53804
Proteomes	UP000005640
Bgee	P53804
CleanEx	HS_TTC3
ExpressionAtlas	P53804
Genevestigator	P53804
GO	GO:0005739 GO:0005634 GO:0005773 GO:0016874 GO:0004842 GO:0008270 GO:0010771 GO:0045665 GO:0070936 GO:0006511
Gene3D	1.25.40.10 3.30.40.10
InterPro	IPR013026 IPR011990 IPR001440 IPR019734 IPR001841 IPR013083
Pfam	PF00515 PF13639
SMART	SM00184 SM00028
PROSITE	PS50005 PS50293 PS50089

Annotations

Qualifier	GO ID	GO term name	Reference	ECO ID	ECO term name	with/from	Aspect	Extension	Notes	Status
involved_in	GO:0070936	protein K48-linked ubiquitination	PMID:20059950	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
involved_in	GO:0006511	ubiquitin-dependent protein catabolic process	PMID:20059950	ECO:0000314	direct assay evidence used in manual assertion		P		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	PMID:20059950	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
enables	GO:0004842	ubiquitin-protein transferase activity	PMID:20059950	ECO:0000314	direct assay evidence used in manual assertion		F		Seeded From UniProt	complete
involved_in	GO:0006511	ubiquitin-dependent protein catabolic process		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000529385 UniProtKB:P53804	P		Seeded From UniProt	complete
enables	GO:0004842	ubiquitin-protein transferase activity		ECO:0000318	biological aspect of ancestor evidence used in manual assertion	PANTHER:PTN000529385 UniProtKB:P53804	F		Seeded From UniProt	complete
part_of	GO:0005829	cytosol	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005730	nucleolus	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000052	ECO:0000314	direct assay evidence used in manual assertion		C		Seeded From UniProt	complete
part_of	GO:0005634	nucleus	GO_REF:0000037 GO_REF:0000039	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0539 UniProtKB-SubCell:SL-0191	C		Seeded From UniProt	complete
enables	GO:0016740	transferase activity	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0808	F		Seeded From UniProt	complete
enables	GO:0046872	metal ion binding	GO_REF:0000037	ECO:0000322	imported manually asserted information used in automatic assertion	UniProtKB-KW:KW-0479	F		Seeded From UniProt	complete
involved_in	GO:0016567	protein ubiquitination	GO_REF:0000041	ECO:0000322	imported manually asserted information used in automatic assertion	UniPathway:UPA00143	P		Seeded From UniProt	complete
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